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Sigesbeckia orientalis L. Derived Active Fraction Ameliorates Perioperative Neurocognitive Disorders Through Alleviating Hippocampal Neuroinflammation Journal article
Frontiers in Pharmacology, 2022,Volume: 13
Authors:  Chu, John Man Tak;  Abulimiti, Amina;  Wong, Brian Shing Hei;  Zhao, Guan Ding;  Xiong, Shi Hang;  Zhao, Ming Ming;  Wang, Yingyi;  Chen, Ying;  Wang, Jiaqi;  Zhang, Yan;  Chang, Raymond Chuen Chung;  Yu, Hua;  Wong, Gordon Tin Chun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
microglia  neuroinflammation  perioperative neurocognitive disorders  Sigesbeckia orientalis L  surgery  
Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs Journal article
Carbohydrate Polymers, 2021,Volume: 266
Authors:  Xiong, Wei;  Xiong, Shi Hang;  Chen, Qi Ling;  Linghu, Ke Gang;  Zhao, Guan Ding;  Chu, John M.T.;  Wong, Gordon T.C.;  Li, Juan;  Hu, Yuan Jia;  Wang, Yi Tao;  Yu, Hua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/13
Berberine  Brij-grafted-chitosan  Diabetic Kidney Disease  Oral Nanocarrier  P-glycoprotein  
Botany, traditional use, phytochemistry, pharmacology and toxicology of Sigesbeckiae Herba (Xixiancao): a review Journal article
Phytochemistry Reviews, 2021
Authors:  Tao,Hong Xun;  Zhao,Guan Ding;  Linghu,Ke Gang;  Xiong,Wei;  Sang,Wei;  Peng,Yu;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:6 TC[Scopus]:4 | Submit date:2021/03/02
Pharmacology  Phytochemistry  Sigesbeckiae Herba  Toxicology  Traditional Use  
Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Linghu,Ke Gang;  Xiong,Shi Hang;  Zhao,Guan Ding;  Zhang,Tian;  Xiong,Wei;  Zhao,Mingming;  Shen,Xiang Chun;  Xu,Wei;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/02
Inflammation  Mh7a  Rheumatoid Arthritis  Sigesbeckia Orientalisl  Sw982  Synovial Hyperplasia  
Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Ma,Qiu Shuo;  Linghu,Ke Gang;  Zhang,Tian;  Zhao,Guan Ding;  Xiong,Wei;  Xiong,Shi Hang;  Zhao,Mingming;  Xu,Wei;  Yu,Juan;  Yu,Hua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/02
Inflammation  Nuclear Transcription Factor-kappa b  Rheumnnatoid Arthritis  Sigesbeckia Glabrescens Makino  Sw982  Synovial Hyperplasia  
Comprehensive comparison on the anti-inflammatory effects of three species of Sigesbeckia plants based on NF-κB and MAPKs signal pathways in vitro Journal article
Journal of Ethnopharmacology, 2020,Volume: 250
Authors:  Linghu,Ke Gang;  Zhao,Guan Ding;  Xiong,Wei;  Sang,Wei;  Xiong,Shi Hang;  Tse,Anfernee Kai Wing;  Hu,Yuanjia;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2021/03/01
Anti-inflammation  Mapks  Nf-κb  Sigesbeckia Glabrescens Makino  Sigesbeckia OrientaL.s L.  Sigesbeckia Pubescens Makino  
Leocarpinolide B attenuates LPS-induced inflammation on RAW264.7 macrophages by mediating NF-κB and Nrf2 pathways Journal article
European Journal of Pharmacology, 2020,Volume: 868
Authors:  Linghu,Ke Gang;  Ma,Qiu Shuo;  Zhao,Guan Ding;  Xiong,Wei;  Lin,Ligen;  Zhang,Qing Wen;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:9 TC[Scopus]:9 | Submit date:2021/03/01
Leocarpinolide b  Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)  Nuclear Transcription Factor-kappa b (Nf-κb)  Rheumatoid Arthritis (Ra)  Sigesbeckiae Herba (Sh)  
Immunomodulatory effects of a new whole ingredients extract from Astragalus: a combined evaluation on chemistry and pharmacology Journal article
CHINESE MEDICINE, 2019,Volume: 14
Authors:  Zhi Xin Li;  Guan Ding Zhao;  Wei Xiong;  Ke Gang Linghu;  Qiu Shuo Ma;  Wai San Cheang;  Hua Yu;  Yitao Wang
Favorite |  | TC[WOS]:12 TC[Scopus]:11 | Submit date:2020/03/10
Whole Ingredients Extract  Chemical Integrity  Immunomodulation  Astragali Radix  
Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations Journal article
Carbohydrate Polymers, 2019,Volume: 204,Page: 89-96
Authors:  Wei Xiong;  Guan Ding Zhao;  Xunqing Yin;  Ke Gang Linghu;  John M.T. Chu;  Gordon T.C. Wong;  Haifeng Li;  Hua Yu;  Yi Tao Wang
Favorite |  | TC[WOS]:12 TC[Scopus]:16 | Submit date:2018/11/15
Chitosan  Brij-s20  Solubility  P-glycoprotein  Drug Efflux  
Siegesbeckia Orientalis L. Extract Attenuates Postoperative Cognitive Dysfunction, Systemic Inflammation, and Neuroinflammation Journal article
EXPERIMENTAL NEUROBIOLOGY, 2018,Volume: 27,Issue: 6,Page: 564-573
Authors:  John Man Tak Chu;  Wei Xiong;  Ke Gang Linghu;  Yan Liu;  Yan Zhang;  Guan Ding Zhao;  Michael G. Irwin;  Gordon Tin Chun Wong;  Hua Yu
Favorite |  | TC[WOS]:13 TC[Scopus]:14 | Submit date:2020/07/13
Surgery  Cognitive Dysfunction  Inflammation  Tau