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Inhibition and structure-activity relationship of dietary flavones against three Loop 1 human gut microbial β-glucuronidases Journal article
International Journal of Biological Macromolecules, 2022
Authors:  Wang, Panpan;  Wu, Rongrong;  Jia, Yifei;  Tang, Puipui;  Zhang, Qingwen;  Wang, Yafan;  Yan, Ru
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/30
Gut Microbial Metabolism  Β-glucuronidases  Gus Inhibitor  Flavones  Structure-activity Relationship  Allosteric Inhibition  
Host UDP-glucuronosyltransferases (UGTs) – gut microbial β-glucuronidases (GUSs) axis in metabolic homeostasis and drug exposure Presentation
报告日期: 2022-06-01
Authors:  Yan, Ru
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/30
Gut Microbial Metabolism  Host Udp-glucuronosyltransferases  Gut Microbial Β-glucuronidases  Host Ugts – Gut Microbial Guss Axis  Metabolic Homeostasis  Drug Exposure  
Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy Journal article
Biochemical Pharmacology, 2021,Volume: 190
Authors:  Wang, Panpan;  Jia, Yifei;  Wu, Rongrong;  Chen, Zhiqiang;  Yan, Ru
Favorite |  | TC[WOS]:11 TC[Scopus]:14 | Submit date:2021/12/08
Β-glucuronidases  Gut Microbial Metabolism  Drug Toxicity  Gus Inhibitor  Gut Microbiota  
Gut microbial beta-glucuronidases: From enterohepatic cirucation to medication modulation (肠道菌β-葡萄糖醛酸苷酶:从肠肝循环到药物治疗调控) Presentation
报告日期: 2021-04-01
Authors:  Yan, Ru
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/30
Gut Microbial Metabolism  Β-glucuronidases  Enterohepatic Cirucation  Medication Modulation  
Combination Inhibition of Gut Microbial β-Glucuronidase Metabolism and Intestinal Uptake by MSK Attenuated Irinotecan-induced Gastrointestinal Toxicity in Mice Conference proceedings
Authors:  Wang, Panpan;  Hou, Tingting;  Wu, Rongrong;  Yan, Ru
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/15
Β-glucuronidases  Combination Inhibition  Gut Microbial Metabolism  Irinotecan  Gastrointestinal Toxicity  Intestinal Uptake  Sn-38g  Mori Cortex  Da Adducts  
Ginseng polysaccharides enhanced ginsenoside Rb1 and microbial metabolites exposure through enhancing intestinal absorption and affecting gut microbial metabolism Journal article
Journal of Ethnopharmacology, 2018,Volume: 216,Page: 47-56
Authors:  Shen, Hong;  Gao, Xue-Jiao;  Li, Ting;  Jing, Wang-Hui;  Han, Bei-Lei;  Jia, Yu-Meng;  Hu, Nan;  Yan, Zhi-Xiang;  Li, Song-Lin;  Yan, Ru
Favorite |  | TC[WOS]:53 TC[Scopus]:65 | Submit date:2018/10/30
Oral Pharmacokinetics  Polysaccharides  Ginsenoside Rb1  Gut Microbial Metabolism  Pharmacokinetic Interactions  Intestinal Absorption  Systemic Exposure  Ginseng  
β-Glucuronidase from Staphylococcus pasteuri 3I10: Activity, inhibition and expression Conference proceedings
Authors:  Yan R(燕茹)
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/15
Β-glucuronidase  Staphylococcus Pasteuri  Gut Microbiota  Deglucuronidation  Gus Inhibitor  Gut Microbial Metabolism  
The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility Journal article
Nutrients nutrients, 2016,Volume: 8,Issue: 2
Authors:  Tugba Ozdal;  David A. Sela;  Jianbo Xiao;  Dilek Boyacioglu;  Fang Chen;  Esra Capanoglu
Favorite |  | TC[WOS]:412 TC[Scopus]:446 | Submit date:2019/01/24
Polyphenols  Phenolics  Flavonoids  Gut Microbiota  Microbial Metabolism  Bioavailability  Health  Interactions  
The presystemic interplay between gut microbiota and orally administered calycosin-7-O-β-D-Glucoside Journal article
Drug Metabolism and Disposition, 2015,Volume: 43,Issue: 10,Page: 1601-1611
Authors:  Jian-Qing Ruan;  Shang Li;  Ya-Ping Li;  Wen-Jin Wu;  Simon Ming-Yuen Lee;  Ru Yan
Favorite |  | TC[WOS]:25 TC[Scopus]:29 | Submit date:2018/11/06
Gut Microbiota  Presystematic Interactions  Pharmacokinetics  Astragali Radix  Chinese Medicines  Calycosin-7-o-β-d-glucoside  Gut Microbial Metabolism  Glucuronidation  Flavonoids  
Oral pharmacokinetics of baicalin, wogonoside, oroxylin A 7-O-β-D-glucuronide and their aglycones from an aqueous extract of Scutellariae Radix in the rat Journal article
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2015,Volume: 1026,Page: 124-133
Authors:  Yu Cai;  Sai Li;  Ting Li;  Ruina Zhou;  Alfred Tai-Seng Wai;  Ru Yan
Favorite |  | TC[WOS]:33 TC[Scopus]:40 | Submit date:2018/10/30
Pharmacokinetics  Hepatic Glucuronidation  Intestinal Permeability  Gut Microbial Metabolism  Isomerization  Scutellaria Radix  Systemic Exposure  Β-glucuronidases