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ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy Journal article
Acta Biomaterialia, 2022,Volume: 140,Page: 492-505
Authors:  Yang, Suleixin;  Wong, Ka Hong;  Hua, Peng;  He, Chengwei;  Yu, Hua;  Shao, Dan;  Shi, Zhi;  Chen, Meiwan
Favorite |  | TC[WOS]:0 TC[Scopus]:2 | Submit date：2022/03/28
Ferroptosis  Fluorinated Polyethyleneimine Vector  Gpx4  Mthfd2  
Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways Journal article
Biochemical Pharmacology, 2022,Volume: 197
Authors:  Tu, Yanbei;  Tan, Lihua;  Lu, Tao;  Wang, Kai;  Wang, Haiyong;  Han, Bing;  Zhao, Yuxin;  Chen, Hanbin;  Li, Yanfang;  Chen, Haixia;  Chen, Meiwan;  He, Chengwei
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/03/28
Glycine Tabacina  Glytabastan b  Inflammation  Network Pharmacology  Osteoclast  Rheumatoid Arthritis  
Spheroidization of ultrasonic degraded corn silk polysaccharide to enhance bioactivity by the anti-solvent precipitation method Journal article
Journal of the Science of Food and Agriculture, 2022,Volume: 102,Issue: 1,Page: 53-61
Authors:  Jia, Yanan;  Lu, Yangpeng;  Wang, Yajie;  Zhang, Min;  He, Chengwei;  Chen, Haixia
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date：2022/02/21
Corn Silk Polysaccharide  Glut4  Spheroidization  Ultrasonic Degradation  Α-glucosidase  
Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine Journal article
Acta Pharmaceutica Sinica B, 2022
Authors:  Wang, Xuan;  Hua, Peng;  He, Chengwei;  Chen, Meiwan
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/17
Anticancer  Autophagy  Combination therapies  Ferroptosis  Nanomedicine  Necroptosis  Non-apoptotic cell death  Pyroptosis  
Polysaccharides from mulberry (Morus alba L.) leaf prevents obesity by inhibiting pancreatic lipase in high-fat diet induced mice Journal article
International Journal of Biological Macromolecules, 2021,Volume: 192,Page: 452-460
Authors:  Li, Ruilin;  Xue, Zihan;  Jia, Yanan;  Wang, Yajie;  Li, Shuqin;  Zhou, Jingna;  Liu, Junyu;  Zhang, Min;  He, Chengwei;  Chen, Haixia
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date：2021/12/08
Interaction Mechanism  Mulberry Leaf Polysaccharides  Pancreatic Lipase  
Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy Journal article
Journal of Cancer Research and Clinical Oncology, 2021,Volume: 147,Issue: 12,Page: 3653-3664
Authors:  Zhao, Yuxin;  Wang, Haiyong;  He, Chengwei
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date：2021/12/08
Drug Resistance  Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor  Non-small Cell Lung Cancer  Targeted Therapy  
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Zhang, Chao;  Li, Qingrui;  Qin, Guozheng;  Zhang, Yi;  Li, Chaoying;  Han, Liwen;  Wang, Rongchun;  Wang, Shudan;  Chen, Haixia;  Liu, Kechun;  He, Chengwei
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date：2021/12/09
Anti-angiogenesis  Anti-metastasis  Hepatocellular Carcinoma Cells  Nf-κb/mmp-9/vegf Pathway  Polyphyllin Vii  
A combined network pharmacology and molecular biology approach to investigate the active ingredients and potential mechanisms of mulberry (Morus alba L.) leaf on obesity Journal article
Phytomedicine, 2021,Volume: 92
Authors:  Li, Ruilin;  Wang, Chunli;  Chen, Yue;  Li, Nannan;  Wang, Qirou;  Zhang, Min;  He, Chengwei;  Chen, Haixia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/12/08
Hypolipidemic  Mulberry Leaf  Network Pharmacology  Obesity  Pi3k/akt/bcl-xl Signaling Pathways  
Effect of Fe (III), Zn (II), and Cr (III) complexation on the physicochemical properties and bioactivities of corn silk polysaccharide Journal article
International Journal of Biological Macromolecules, 2021,Volume: 189,Page: 847-856
Authors:  Jia, Yanan;  Li, Nannan;  Wang, Qirou;  Zhou, Jingna;  Liu, Junyu;  Zhang, Min;  He, Chengwei;  Chen, Haixia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/13
antioxidant activity  Corn silk polysaccharide  Metal chelation  Physicochemical property  α-glucosidase inhibition  
The structural characteristic of acidic-hydrolyzed corn silk polysaccharides and its protection on the H2O2-injured intestinal epithelial cells Journal article
Food Chemistry, 2021,Volume: 356
Authors:  Jia, Yanan;  Wang, Yajie;  Li, Ruilin;  Li, Shuqin;  Zhang, Min;  He, Chengwei;  Chen, Haixia
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date：2021/12/08
Acidic-hydrolyzation  Antioxidant Activity  Corn Silk Polysaccharides  Intestinal Epithelial Cells