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ROS-responsive fluorinated polyethyleneimine vector to co-deliver shMTHFD2 and shGPX4 plasmids induces ferroptosis and apoptosis for cancer therapy
Journal article
Acta Biomaterialia, 2022,Volume: 140,Page: 492-505
Authors:
Yang, Suleixin
;
Wong, Ka Hong
;
Hua, Peng
;
He, Chengwei
;
Yu, Hua
;
Shao, Dan
;
Shi, Zhi
;
Chen, Meiwan
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TC[WOS]:
0
TC[Scopus]:
2
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Submit date:2022/03/28
Ferroptosis
Fluorinated Polyethyleneimine Vector
Gpx4
Mthfd2
Glytabastan B, a coumestan isolated from Glycine tabacina, alleviated synovial inflammation, osteoclastogenesis and collagen-induced arthritis through inhibiting MAPK and PI3K/AKT pathways
Journal article
Biochemical Pharmacology, 2022,Volume: 197
Authors:
Tu, Yanbei
;
Tan, Lihua
;
Lu, Tao
;
Wang, Kai
;
Wang, Haiyong
;
Han, Bing
;
Zhao, Yuxin
;
Chen, Hanbin
;
Li, Yanfang
;
Chen, Haixia
;
Chen, Meiwan
;
He, Chengwei
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/03/28
Glycine Tabacina
Glytabastan b
Inflammation
Network Pharmacology
Osteoclast
Rheumatoid Arthritis
Spheroidization of ultrasonic degraded corn silk polysaccharide to enhance bioactivity by the anti-solvent precipitation method
Journal article
Journal of the Science of Food and Agriculture, 2022,Volume: 102,Issue: 1,Page: 53-61
Authors:
Jia, Yanan
;
Lu, Yangpeng
;
Wang, Yajie
;
Zhang, Min
;
He, Chengwei
;
Chen, Haixia
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TC[WOS]:
0
TC[Scopus]:
1
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Submit date:2022/02/21
Corn Silk Polysaccharide
Glut4
Spheroidization
Ultrasonic Degradation
Α-glucosidase
Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine
Journal article
Acta Pharmaceutica Sinica B, 2022
Authors:
Wang, Xuan
;
Hua, Peng
;
He, Chengwei
;
Chen, Meiwan
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/17
Anticancer
Autophagy
Combination therapies
Ferroptosis
Nanomedicine
Necroptosis
Non-apoptotic cell death
Pyroptosis
Polysaccharides from mulberry (Morus alba L.) leaf prevents obesity by inhibiting pancreatic lipase in high-fat diet induced mice
Journal article
International Journal of Biological Macromolecules, 2021,Volume: 192,Page: 452-460
Authors:
Li, Ruilin
;
Xue, Zihan
;
Jia, Yanan
;
Wang, Yajie
;
Li, Shuqin
;
Zhou, Jingna
;
Liu, Junyu
;
Zhang, Min
;
He, Chengwei
;
Chen, Haixia
Favorite
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TC[WOS]:
1
TC[Scopus]:
2
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Submit date:2021/12/08
Interaction Mechanism
Mulberry Leaf Polysaccharides
Pancreatic Lipase
Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy
Journal article
Journal of Cancer Research and Clinical Oncology, 2021,Volume: 147,Issue: 12,Page: 3653-3664
Authors:
Zhao, Yuxin
;
Wang, Haiyong
;
He, Chengwei
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TC[WOS]:
2
TC[Scopus]:
4
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Submit date:2021/12/08
Drug Resistance
Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor
Non-small Cell Lung Cancer
Targeted Therapy
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo
Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:
Zhang, Chao
;
Li, Qingrui
;
Qin, Guozheng
;
Zhang, Yi
;
Li, Chaoying
;
Han, Liwen
;
Wang, Rongchun
;
Wang, Shudan
;
Chen, Haixia
;
Liu, Kechun
;
He, Chengwei
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TC[WOS]:
3
TC[Scopus]:
3
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Submit date:2021/12/09
Anti-angiogenesis
Anti-metastasis
Hepatocellular Carcinoma Cells
Nf-κb/mmp-9/vegf Pathway
Polyphyllin Vii
A combined network pharmacology and molecular biology approach to investigate the active ingredients and potential mechanisms of mulberry (Morus alba L.) leaf on obesity
Journal article
Phytomedicine, 2021,Volume: 92
Authors:
Li, Ruilin
;
Wang, Chunli
;
Chen, Yue
;
Li, Nannan
;
Wang, Qirou
;
Zhang, Min
;
He, Chengwei
;
Chen, Haixia
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/12/08
Hypolipidemic
Mulberry Leaf
Network Pharmacology
Obesity
Pi3k/akt/bcl-xl Signaling Pathways
Effect of Fe (III), Zn (II), and Cr (III) complexation on the physicochemical properties and bioactivities of corn silk polysaccharide
Journal article
International Journal of Biological Macromolecules, 2021,Volume: 189,Page: 847-856
Authors:
Jia, Yanan
;
Li, Nannan
;
Wang, Qirou
;
Zhou, Jingna
;
Liu, Junyu
;
Zhang, Min
;
He, Chengwei
;
Chen, Haixia
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
antioxidant activity
Corn silk polysaccharide
Metal chelation
Physicochemical property
α-glucosidase inhibition
The structural characteristic of acidic-hydrolyzed corn silk polysaccharides and its protection on the H2O2-injured intestinal epithelial cells
Journal article
Food Chemistry, 2021,Volume: 356
Authors:
Jia, Yanan
;
Wang, Yajie
;
Li, Ruilin
;
Li, Shuqin
;
Zhang, Min
;
He, Chengwei
;
Chen, Haixia
Favorite
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TC[WOS]:
8
TC[Scopus]:
8
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Submit date:2021/12/08
Acidic-hydrolyzation
Antioxidant Activity
Corn Silk Polysaccharides
Intestinal Epithelial Cells