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Induction of an MLKL mediated non-canonical necroptosis through reactive oxygen species by tanshinol A in lung cancer cells Journal article
Biochemical Pharmacology, 2020,Volume: 171
Authors:  Liu,Xin;  Zhang,Yiying;  Gao,Hongwei;  Hou,Ying;  Lu,Jin jian;  Feng,Yulin;  Xu,Qiongming;  Liu,Bo;  Chen,Xiuping
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/01
Lung cancer  MLKL  Programmed necrosis  ROS  Tanshinol A  
Inhibition of Lung Cancer by 2-Methoxy-6-Acetyl-7-Methyljuglone Through Induction of Necroptosis by Targeting Receptor-Interacting Protein 1 Journal article
Antioxidants and Redox Signaling, 2019,Volume: 31,Issue: 2,Page: 93-108
Authors:  Sun,Wen;  Yu,Jie;  Gao,Hongwei;  Wu,Xiaxia;  Wang,Sheng;  Hou,Ying;  Lu,Jin Jian;  Chen,Xiuping
Favorite |  | TC[WOS]:8 TC[Scopus]:10 | Submit date:2021/03/01
cancer  drug resistance  MAM  necroptosis  RIP1  
Dihydronortanshinone, a natural product, alleviates LPS-induced inflammatory response through NF-κB, mitochondrial ROS, and MAPK pathways Journal article
Toxicology and Applied Pharmacology, 2018,Volume: 355,Page: 1-8
Authors:  Xiaxia Wu;  Hongwei Gao;  Ying Hou;  Jie Yu;  Wen Sun;  Ying Wang;  Xiaoyan Chen;  Yulin Feng;  Qiong-ming Xu;  Xiuping Chen
Favorite |  | TC[WOS]:19 TC[Scopus]:19 | Submit date:2018/12/28
Dihydronortanshinone  Inflammation  Lps  Macrophage  
2-methoxy-6-acetyl-7-methyljuglone (MAM) induces iNOS/NO-mediated DNA damage response through activation of MAPKs pathways Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2018,Volume: 18,Issue: 6,Page: 903-913
Authors:  Niu,Yanan;  Yuan,Renyikun;  Gao,Hongwei;  Lu,Jin Jian;  Kong,Qi;  Chen,Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/03/01
ATM/Chk2  DNA damage  iNOS/NO  L-arginine  MAM  MAPKs  
Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization Journal article
BRITISH JOURNAL OF PHARMACOLOGY, 2017,Volume: 174,Issue: 17,Page: 2880-2896
Authors:  Gao, Hongwei;  Cui, Yankun;  Kang, Naixin;  Liu, Xin;  Liu, Yanli;  Zou, Yue;  Zhang, Ziyu;  Li, Xiaoran;  Yang, Shilin;  Li, Ji;  Wang, Chunming;  Xu, Qiong-ming;  Chen, Xiuping
Favorite |  | TC[WOS]:18 TC[Scopus]:22 | Submit date:2018/10/30
Total tanshinones exhibits anti-inflammatory effects through blocking TLR4 dimerization via the MyD88 pathway Journal article
CELL DEATH & DISEASE, 2017,Volume: 8
Authors:  Gao, Hongwei;  Liu, Xin;  Sun, Wen;  Kang, Naixin;  Liu, Yanli;  Yang, Shilin;  Xu, Qiong-ming;  Wang, Chunming;  Chen, Xiuping
Favorite |  | TC[WOS]:25 TC[Scopus]:26 | Submit date:2018/10/30
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2017,Volume: 108,Page: 433-444
Authors:  Sun, Wen;  Wu, Xiaxia;  Gao, Hongwei;  Yu, Jie;  Zhao, Wenwen;  Lu, Jin-Jian;  Wang, Jinhua;  Du, Guanhua;  Chen, Xiuping
Favorite |  | TC[WOS]:53 TC[Scopus]:55 | Submit date:2018/10/30
Necroptosis  C-jun N-terminal Kinase  Calcium  Ros  
Chemical constituents and biological research on plants in the genus Curcuma Journal article
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2017,Volume: 57,Issue: 7,Page: 1451-1523
Authors:  Sun, Wen;  Wang, Sheng;  Zhao, Wenwen;  Wu, Chuanhong;  Guo, Shuhui;  Gao, Hongwei;  Tao, Hongxun;  Lu, Jinjian;  Wang, Yitao;  Chen, Xiuping
Favorite |  | TC[WOS]:23 TC[Scopus]:29 | Submit date:2018/10/30
Genus Curcuma  Chemical Constituents  Bioactivities  Antitumor