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Psoralidin, a natural compound from Psoralea corylifolia, induces oxidative damage mediated apoptosis in colon cancer cells Journal article
Journal of Biochemical and Molecular Toxicology, 2022
Authors:  Sun, Chong;  Zhao, Lin;  Wang, Xianzhe;  Hou, Ying;  Guo, Xiuli;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/17
Apoptosis  Cell Death  Ros  Chinese Medicine  
Exogenous iron impairs the anti-cancer effect of ascorbic acid both in vitro and in vivo Journal article
Journal of Advanced Research, 2022
Authors:  Zhong, Bingling;  Zhao, Lin;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Lu, Jin Jian;  Ge, Wei;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/08/05
Ascorbic acid  Ca2+  Iron  Necrosis  ROS  
Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase-independent apoptosis through cyclin D1 downregulation in colon cancer in vivo Journal article
Pharmacological Research, 2021,Volume: 173
Authors:  Hou, Ying;  Liu, Rong;  Xia, Mengwei;  Sun, Chong;  Zhong, Bingling;  Yu, Jie;  Ai, Nana;  Lu, Jin Jian;  Ge, Wei;  Liu, Bo;  Chen, Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date：2021/12/08
Apoptosis  Cyclin D1  G1 Cell Cycle Arrest  Nannocystin Ax  
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65 Journal article
Phytotherapy Research, 2021,Volume: 35,Issue: 10,Page: 5861-5870
Authors:  Zhou, Yishan;  Zhong, Bingling;  Min, Xiangjing;  Hou, Ying;  Lin, Ligen;  Wu, Qin;  Shi, Jingshan;  Chen, Xiuping
Favorite |  | TC[WOS]:4 TC[Scopus]:6 | Submit date：2021/12/08
Inflammation  Isobavachalcone  Nf-κb P65  Ulcerative Colitis  
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1) Journal article
Free Radical Biology and Medicine, 2021,Volume: 173,Page: 64-69
Authors:  Yu, Jie;  Zhong, Bingling;  Zhao, Lin;  Hou, Ying;  Wang, Xianzhe;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/12/08
Nec-1  Nec-1s  Nqo1  Ripk1  
Nannocystin Ax, a natural elongation factor 1α inhibitor from Nannocystis sp., suppresses epithelial-mesenchymal transition, adhesion and migration in lung cancer cells Journal article
Toxicology and Applied Pharmacology, 2021,Volume: 420
Authors:  Sun, Chong;  Liu, Rong;  Xia, Mengwei;  Hou, Ying;  Wang, Xumei;  Lu, Jin jian;  Liu, Bo;  Chen, Xiuping
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/12/08
Emt  Cancer  Metastasis  Nannocystin Ax  
A four-component combination derived from Huang-Qin Decoction significantly enhances anticancer activity of irinotecan Journal article
Chinese Journal of Natural Medicines, 2021,Volume: 19,Issue: 5,Page: 364-375
Authors:  XU, Dou Dou;  HOU, Xiao Ying;  WANG, Ou;  WANG, Di;  LI, Dan Ting;  QIN, Si Yuan;  LV, Bo;  DAI, Xiao Min;  ZHANG, Zun Jian;  WAN, Jian Bo;  XU, Feng Guo
Favorite |  | TC[WOS]:2 TC[Scopus]:4 | Submit date：2021/12/07
Active Components  Bioactivity Contribution  Huang-qin Decoction  Irinotecan  Toxicity Attenuating And Efficacy Enhancing  
A novel strategy for glioblastoma treatment by induction of noptosis, an NQO1-dependent necrosis Journal article
Free Radical Biology and Medicine, 2021,Volume: 166,Page: 104-115
Authors:  Zhong, Bingling;  Yu, Jie;  Hou, Ying;  Ai, Nana;  Ge, Wei;  Lu, Jin Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date：2021/09/17
Cell Death  Danshen  Noptosis  Nqo1  
Bioactive Limonoids and Triterpenoids from the Fruits of Melia azedarach Journal article
Journal of Natural Products, 2020,Volume: 83,Issue: 12,Page: 3502-3510
Authors:  Song,Min;  Zhang,Jian;  Chan,Ging;  Hou,Ying;  Chen,Xiu Ping;  Zhang,Xiao Qi;  Ye,Wen Cai;  Zhang,Qing Wen
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date：2021/03/01
Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds Journal article
Pharmacology and Therapeutics, 2020,Volume: 214
Authors:  Yu,Jie;  Zhong,Bingling;  Xiao,Qingwen;  Du,Lida;  Hou,Ying;  Sun,Hong Shuo;  Lu,Jin Jian;  Chen,Xiuping
Favorite |  | TC[WOS]:15 TC[Scopus]:16 | Submit date：2021/03/01
Cancer  Cell Death  Ros  Apoptosis