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Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors:  Huang,Mu Yang;  Jiang,Xiao Ming;  Wang,Bing Lin;  Sun,Yang;  Lu,Jin Jian
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/03/02
Challenge  Combination Therapy  Immunotherapy  Mechanism  Nsclc  Pd-1/pd-l1  
Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors:  Yuan,Luo Wei;  Jiang,Xiao Ming;  Xu,Yu Lian;  Huang,Mu Yang;  Chen,Yu Chi;  Yu,Wei Bang;  Su,Min Xia;  Ye,Zi Han;  Chen,Xiuping;  Wang,Yitao;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Ifn-γ  Licochalcone a  Natural Products  Pd-l1  Protein Synthesis Inhibitor  Ros  
Regulation of CD47 expression in cancer cells Journal article
Translational Oncology, 2020,Volume: 13,Issue: 12
Authors:  Huang,Can Yu;  Ye,Zi Han;  Huang,Mu Yang;  Lu,Jin Jian
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/02
Cd47  Cytokine  Microrna  Oncogene  Qpctl  
Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics Journal article
Food Chemistry, 2020,Volume: 327
Authors:  Zhang,Le Le;  Huang,Mu Yang;  Yang,Yong;  Huang,Ming Qing;  Shi,Jia Jie;  Zou,Liang;  Lu,Jin Jian
Favorite |  | TC[WOS]:11 TC[Scopus]:12 | Submit date:2021/03/02
Pharmacokinetics  Pharmacological Activities  Phytochemistry  Platycodins  Platycodonis Radix  Toxicology  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020,Volume: 42,Issue: 3,Page: 451-459
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/01
Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming;  YUAN,Luo Wei;  HUANG,Run Yue;  LIU,Bo;  YU,Hua;  WANG,Yi Tao;  CHEN,Xiu Ping;  LIN,Li Gen;  LU,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
C-jun  Jnk  Lung Cancer  Nagilactone e  Programmed Death Ligand 1  
SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts Journal article
Virologica Sinica, 2020,Volume: 35,Issue: 3,Page: 321-329
Authors:  Shu,Ting;  Huang,Muhan;  Wu,Di;  Ren,Yujie;  Zhang,Xueyi;  Han,Yang;  Mu,Jingfang;  Wang,Ruibing;  Qiu,Yang;  Zhang,Ding Yu;  Zhou,Xi
Favorite |  | TC[WOS]:47 TC[Scopus]:54 | Submit date:2021/03/02
Antiviral Target  Helicase  Nsp13  Ntpase  Sars-coronavirus-2 (Sars-cov-2)  
Platycodin D triggers the extracellular release of programed death Ligand-1 in lung cancer cells Journal article
FOOD AND CHEMICAL TOXICOLOGY, 2019,Volume: 131
Authors:  Mu-Yang Huang;  Xiao-Ming Jiang;  Yu-Lian Xu;  Luo-Wei Yuan;  Yu-Chi Chen;  Guozhen Cui;  Run-Yue Huang;  Bo Liu;  Yitao Wang;  Xiuping Chen;  Jin-Jian Lu
Favorite |  | TC[WOS]:15 TC[Scopus]:17 | Submit date:2019/11/22
Programmed Death Ligand-1  Platycodin d  Extracellular Release  Natural Products  Cancer  
Nagilactone E suppresses TGF-beta 1-induced epithelial-mesenchymal transition, migration and invasion in non-small cell lung cancer cells Journal article
PHYTOMEDICINE, 2019,Volume: 52,Page: 32-39
Authors:  Le-Le Zhang;  Xiao-Ming Jiang;  Mu-Yang Huang;  Zhe-Ling Feng;  Xiuping Chen;  Yitao Wang;  Hua Li;  Ao Li;  Li-Gen Lin;  Jin-Jian Lu
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2020/01/09
Nagilactone e  Tgf-β1  Epithelial-mesenchymal Transitio  Smad  
A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population Journal article
Neurobiology of Aging, 2018,Volume: 68,Page: 160.e1-160.e7
Authors:  Wang B.;  Bao S.;  Zhang Z.;  Zhou X.;  Wang J.;  Fan Y.;  Zhang Y.;  Li Y.;  Chen L.;  Jia Y.;  Li J.;  Li M.;  Zheng W.;  Mu N.;  Wang L.;  Yu Z.;  Wong D.S.M.;  Zhang Y.;  Kwan J.;  Ka-Fung Mak H.;  Ambalavanan A.;  Zhou S.;  Cai W.;  Zheng J.;  Huang S.;  Rouleau G.A.;  Yang W.;  Rogaeva E.;  Ma X.;  St George-Hyslop P.;  Chu L.W.;  Song Y.-Q.
Favorite |  | TC[WOS]:9 TC[Scopus]:8 | Submit date:2018/12/21
Apoe Ɛ4-negative  Late-onset Alzheimer's Disease  Mlkl  Whole Exome Sequencing