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Cell metabolomics study on the anticancer effects of Ophiopogon japonicus against lung cancer cells using UHPLC/Q-TOF-MS analysis Journal article
Frontiers in Pharmacology, 2022,Volume: 13,Page: 1017830
Authors:  Liu, Qiao;  Shen, Jia-Man;  Hong, Hui-Jie;  Yang, Qi;  Liu, Wen;  Guan, Zhong;  Wang, Yi-tao;  Chen, Xiao-Jia
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Stretched three-dimensional white graphene with a tremendous lattice thermal conductivity increase rate Journal article
RSC Advances, 2022,Volume: 12,Page: 22581
Authors:  Y. Han;  Y. Liang;  X. Liu;  S. Jia;  C. Zhao;  L. Yang;  J. Ding;  Guo Hong;  K. Termentzidis
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Chaperone-Mediated Autophagy in Neurodegenerative Diseases: Molecular Mechanisms and Pharmacological Opportunities Journal article
Cells, 2022,Volume: 11,Issue: 14
Authors:  Wang, Yi Ting;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/24
Alzheimer’s Disease  Autophagy  Chaperone-mediated Autophagy  Hsc70  Huntington’s Disease  Lamp2a  Neurodegenerative Disease  Parkinson’s Disease  Small Molecule  Α-synuclein  
α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation Journal article
Phytomedicine, 2022,Volume: 101
Authors:  Chen, Jia Yue;  Zhu, Qi;  Cai, Cui Zan;  Luo, Hai Bin;  Lu, Jia Hong
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Alpha-synuclein (Α-syn)  Parkinson's Disease  Phosphodiesterase 4 Inhibitor  Protein Kinase a (Pka)  Ubiquitin-proteasome System (Ups)  
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy Journal article
Chinese Medicine, 2022,Volume: 17,Issue: 1
Authors:  Zhang, Shuang;  Dong, Yu;  Chen, Xiuping;  Tan, Chris Soon Heng;  Li, Min;  Miao, Kai;  Lu, Jia Hong
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Apoptosis  Autophagy Inhibition  Irinotecan  Lysosome  Sn-38  Toosendanin  Triple-negative Breast Cancer  
Chemical Comparison of Monk Fruit Products Processed by Different Drying Methods Using High-Performance Thin-Layer Chromatography Combined With Chemometric Analysis Journal article
Frontiers in Nutrition, 2022,Volume: 9,Page: 887992
Authors:  Hong, Hui-Jie;  Yang, Qi;  Liu, Qiao;  Leong, Fong;  Chen, Xiao-Jia
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Chemical Characteristics  Chemometric Analysis  Drying Method  High Performance Thin Layer Chromatography  Monk Fruit  Siraitia Grosvenorii  
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 Journal article
Acta Pharmacologica Sinica, 2022,Volume: 43,Issue: 5,Page: 1251-1263
Authors:  Yang, Chuan bin;  Liu, Jia;  Tong, Benjamin Chun Kit;  Wang, Zi ying;  Zhu, Zhou;  Su, Cheng fu;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Wu, Jia xi;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Huang, Shi ying;  Cheung, King ho;  Song, Ju xian;  Tan, Jie qiong;  Lu, Jia hong;  Li, Min
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15-deoxy-∆-12,14-prostaglandin J2 (15d-pgJ2)  Apoptosis  Atf4  Autophagy And Lysosome Biogenesis  Er Stress  Transcriptional Factor Eb (tfEb)  
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
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3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
Editorial: Assessing the Pharmacological Effects and Therapeutic Potential of Traditional Chinese Medicine in Neurological Disease Models: An Update Other
2022-04-27
Authors:  Deng, Zhiqiang;  Kan, Yuxuan;  Li, Min;  Song, Juxian;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/05
Dementia  Epilepsy  Multiple Sclerosis  Neurodegenerative Diseases  Stroke  
A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 4,Page: 939-941
Authors:  Ai, Ruixue;  Zhuang, Xu Xu;  Anisimov, Alexander;  Lu, Jia Hong;  Fang, Evandro F.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
Aging  Alzheimer’s Disease  Autophagy  Machine Learning  Mitophagy