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A TNFR2 antibody by countering immunosuppression cooperates with HMGN1 and R848 immune stimulants to inhibit murine colon cancer Journal article
International Immunopharmacology, 2021,Volume: 101
Authors:  Jiang, Mengmeng;  Liu, Jia;  Yang, De;  Tross, Debra;  Li, Ping;  Chen, Fengyang;  Alam, Md Masud;  Faustman, Denise L.;  Oppenheim, Joost J.;  Chen, Xin
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/12/08
Antitumor  cd4+foxp3+ Regulatory t Cells (Tregs)  Hmgn1 And R848  Immunotherapy  Tnfr2  
Inhibition of two-pore channels in antigen-presenting cells promotes the expansion of TNFR2-expressing CD4+Foxp3+ regulatory T cells Journal article
Science Advances, 2020,Volume: 6,Issue: 40
Authors:  He,Tianzhen;  Yang,De;  Li,Xiao Qing;  Jiang,Mengmeng;  Islam,Md Sahidul;  Chen,Shaokui;  Chen,Yibo;  Yang,Yang;  Chou,Chon Kit;  Trivett,Anna L.;  Oppenheim,Joost J.;  Chen,Xin
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date：2021/03/01
Blockade of TNFR2 signaling enhances the immunotherapeutic effect of CpG ODN in a mouse model of colon cancer Journal article
SCIENCE SIGNALING, 2018,Volume: 11,Issue: 511
Authors:  Nie, Yingjie;  He, Jiang;  Shirota, Hidekazu;  Trivett, Anna L.;  Yang, De;  Klinman, Dennis M.;  Oppenheim, Joost J.;  Chen, Xin
Favorite |  | TC[WOS]:30 TC[Scopus]:33 | Submit date：2018/10/30
Development of a Curative Therapeutic Vaccine (TheraVac) for the Treatment of Large Established Tumors Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Nie, Yingjie;  Yang, De;  Trivett, Anna;  Han, Zhen;  Xin, Haiyun;  Chen, Xin;  Oppenheim, Joost J.
Favorite |  | TC[WOS]:19 TC[Scopus]:19 | Submit date：2018/10/30
Targeting TNFR2, an immune checkpoint stimulator and oncoprotein, is a promising treatment for cancer Journal article
SCIENCE SIGNALING, 2017,Volume: 10,Issue: 462
Authors:  Chen, Xin;  Oppenheim, Joost J.
Favorite |  | TC[WOS]:31 TC[Scopus]:32 | Submit date：2018/10/30
Th17 cells and Tregs: unlikely allies Journal article
JOURNAL OF LEUKOCYTE BIOLOGY, 2014,Volume: 95,Issue: 5,Page: 723-731
Authors:  Xin Chen;  Joost J. Oppenheim
Favorite |  | TC[WOS]:51 TC[Scopus]:62 | Submit date：2019/01/14
Synergistic anti-tumor effect of a TGFβ inhibitor and cyclophosphamide Journal article
Oncoimmunology, 2014,Volume: 3,Issue: 4
Authors:  Xin Chen;  Lalage M. Wakefield;  Joost J. Oppenheim
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date：2018/11/30
Anti-tgfβ Antibody  Chemoimmunotherapy  Cyclophosphamide  
In vitro generated Th17 cells support the expansion and phenotypic stability of CD4+ Foxp3+ regulatory T cells in vivo Journal article
CYTOKINE, 2014,Volume: 65,Issue: 1,Page: 56-64
Authors:  Qiong Zhou;  Ya Hu;  O.M. Zack Howard;  Joost J. Oppenheim;  Xin Chen
Favorite |  | TC[WOS]:17 TC[Scopus]:17 | Submit date：2019/01/14
Regulatory t Cell  Il-2  Tnf  Tnfr2  Th17  
TNFR2 Is Critical for the Stabilization of the CD4+ Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment Journal article
JOURNAL OF IMMUNOLOGY, 2013,Volume: 190,Issue: 3,Page: 1076-1084
Authors:  Xin Chen;  Xueqing Wu;  Qiong Zhou;  O.M. Zack Howard;  Mihai G. Netea;  Joost J. Oppenheim
Favorite |  | TC[WOS]:174 TC[Scopus]:171 | Submit date：2019/01/14
Contrasting effects of TNF and anti-TNF on the activation of effector T cells and regulatory T cells in autoimmunity Journal article
FEBS LETTERS, 2011,Volume: 585,Issue: 23,Page: 3611-3618
Authors:  Xin Chen;  Joost J. Oppenheim
Favorite |  | TC[WOS]:76 TC[Scopus]:78 | Submit date：2019/01/14
Tnf  Tnfr2  Regulatory t Cells (Tregs)  Effector t Cells (Teffs)