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Single-cell multiomics sequencing reveals the reprogramming defects in embryos generated by round spermatid injection Journal article
Science Advances, 2022,Volume: 8,Issue: 32
Authors:  Wang, Jing;  Zhou, Cai;  Gao, Shuai;  Song, Xiuling;  Yang, Xinyan;  Fan, Jiaqi;  Ren, Shaofang;  Ma, Linzi;  Zhao, Jiexiang;  Cui, Manman;  Song, Ke;  Wang, Mei;  Li, Chaohui;  Zheng, Yi;  Luo, Fang;  Miao, Kai;  Bai, Xiaochun;  Hutchins, Andrew P.;  Li, Lin;  Chang, Gang;  Zhao, Xiao Yang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/09/07
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy Journal article
Chinese Medicine, 2022,Volume: 17,Issue: 1
Authors:  Zhang, Shuang;  Dong, Yu;  Chen, Xiuping;  Tan, Chris Soon Heng;  Li, Min;  Miao, Kai;  Lu, Jia Hong
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date:2022/05/31
Apoptosis  Autophagy Inhibition  Irinotecan  Lysosome  Sn-38  Toosendanin  Triple-negative Breast Cancer  
FGFR2–BRD4 Axis Regulates Transcriptional Networks of Histone 3 Modification and Synergy Between Its Inhibitors and PD-1/PD-L1 in a TNBC Mouse Model Journal article
Frontiers in Immunology, 2022,Volume: 13
Authors:  Lei, Josh Haipeng;  Zhang, Lei;  Wang, Zhenyi;  Peltier, Raoul;  Xie, Yusheng;  Chen, Ganchao;  Lin, Shiqi;  Miao, Kai;  Deng, Chu Xia;  Sun, Hongyan
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
BRD4  epigenetic  FGFR2  immunotherapy  posttranslational modifications  TNBC  
S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy Journal article
Nature Communications, 2022,Volume: 13,Issue: 1
Authors:  Li, Jianjie;  Shu, Xiaodong;  Xu, Jun;  Su, Sek Man;  Chan, Un In;  Mo, Lihua;  Liu, Jianlin;  Zhang, Xin;  Adhav, Ragini;  Chen, Qiang;  Wang, Yuqing;  An, Tingting;  Zhang, Xu;  Lyu, Xueying;  Li, Xiaoling;  Lei, Josh Haipeng;  Miao, Kai;  Sun, Heng;  Xing, Fuqiang;  Zhang, Aiping;  Deng, Chuxia;  Xu, Xiaoling
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2022/05/13
ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of nonapoptotic phosphatidylserine Journal article
Journal of Clinical Investigation, 2022,Volume: 132,Issue: 5
Authors:  Xu, Jun;  Su, Sek Man;  Zhang, Xin;  Chan, Un In;  Adhav, Ragini;  Shu, Xiaodong;  Liu, Jianlin;  Li, Jianjie;  Mo, Lihua;  Wang, Yuqing;  An, Tingting;  Lei, Josh Haipeng;  Miao, Kai;  Deng, Chu Xia;  Xu, Xiaoling
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/03/28
High-throughput membrane-anchored proteome screening reveals PIEZO1 as a promising antibody-drug target for human esophageal squamous cell carcinoma Journal article
Cancer Medicine, 2022,Volume: 11,Issue: 19,Page: 3700-3713
Authors:  Qin, Xun;  Ni, Zhen;  Jiang, Jianjun;  Liu, Xiguang;  Dong, Xiaoying;  Li, Mei;  Miao, Kai;  Rao, Shuan;  Zhang, Wenqing;  Cai, Kaican
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2022/07/29
Antibody-drug Conjugate  Esophageal Squamous Cell Carcinoma  Piezo1  
Tumor heterogeneity reshapes the tumor microenvironment to influence drug resistance Journal article
International Journal of Biological Sciences, 2022,Volume: 18,Issue: 7,Page: 3019-3033
Authors:  Zhang, Aiping;  Miao, Kai;  Sun, Heng;  Deng, Chu Xia
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date:2022/07/29
Drug Resistance  Tumor Heterogeneity  Tumor Microenvironment  
Cancer drug screening with an on-chip multi-drug dispenser in digital microfluidics Journal article
Lab on a Chip, 2021,Volume: 21,Issue: 24,Page: 4749-4759
Authors:  Zhai, Jiao;  Li, Caiwei;  Li, Haoran;  Yi, Shuhong;  Yang, Ning;  Miao, Kai;  Deng, Chuxia;  Jia, Yanwei;  Mak, Pui In;  Martins, Rui P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/01/14
Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy Journal article
Advanced Science, 2021,Volume: 8,Issue: 21
Authors:  Lei, Josh Haipeng;  Lee, Mi Hye;  Miao, Kai;  Huang, Zebin;  Yao, Zhicheng;  Zhang, Aiping;  Xu, Jun;  Zhao, Ming;  Huang, Zenan;  Zhang, Xin;  Chen, Si;  Jiaying, N. G.;  Feng, Yuzhao;  Xing, Fuqiang;  Chen, Ping;  Sun, Heng;  Chen, Qiang;  Xiang, Tingxiu;  Chen, Lin;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/11/30
Brca1  Breast Cancer  Fgfr2 Inhibitor  Fgfr2-s252w  Tumor Slice Culture  
Patient-Derived Organoids Can Guide Personalized-Therapies for Patients with Advanced Breast Cancer Journal article
Advanced Science, 2021,Volume: 8,Issue: 22
Authors:  Chen, Ping;  Zhang, Xu;  Ding, Renbo;  Yang, Linglin;  Lyu, Xueying;  Zeng, Jianming;  Lei, Josh Haipeng;  Wang, Lijian;  Bi, Jiong;  Shao, Nan;  Shu, Ditian;  Wu, Bin;  Wu, Jingbo;  Yang, Zhihui;  Wang, Haiyan;  Wang, Biqiong;  Xiong, Kang;  Lu, Yun;  Fu, Shaozhi;  Choi, Tak Kan;  Lon, Ng Wai;  Zhang, Aiping;  Tang, Dongyang;  Quan, Yingyao;  Meng, Ya;  Miao, Kai;  Sun, Heng;  Zhao, Ming;  Bao, Jiaolin;  Zhang, Lei;  Xu, Xiaoling;  Shi, Yanxia;  Lin, Ying;  Deng, Chuxia
Favorite |  | TC[WOS]:8 TC[Scopus]:14 | Submit date:2021/11/30
Advanced Breast Cancer  Drug Screening  Patient-derived Organoids  Personalized Therapy