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Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels Journal article
Journal of Extracellular Vesicles, 2022,Volume: 11,Issue: 12
Authors:  Chen, Xi;  Li, Jiaqi;  Zhang, Ren;  Zhang, Yao;  Wang, Xiaoxuan;  Leung, Elaine Lai Han;  Ma, Lijuan;  Wong, Vincent Kam Wai;  Liu, Liang;  Neher, Erwin;  Yu, Haijie
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/01/30
Ca2+  exosome  lung cancer  ORAI1  PD-L1  
Down-regulating Nrf2 by tangeretin reverses multiple drug resistance to both chemotherapy and EGFR tyrosine kinase inhibitors in lung cancer Journal article
Pharmacological Research, 2022,Volume: 186
Authors:  Xie, Ying;  Feng, Sen ling;  He, Fang;  Yan, Pei Yu;  Yao, Xiao Jun;  Fan, Xing Xing;  Leung, Elaine Lai Han;  Zhou, Hua
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2023/01/30
Chemotherapy  Drug resistance  EGFR tyrosine kinase inhibitors  Nrf2  Tangeretin  
PA-MSHA induces inflamed tumor microenvironment and sensitizes tumor to anti-PD-1 therapy Journal article
Cell Death and Disease, 2022,Volume: 13,Issue: 11
Authors:  Huang, Min;  He, Fang;  Li, Dan;  Xie, Ya Jia;  Jiang, Ze Bo;  Huang, Ju Min;  Zhao, Xiao Ping;  Nasim, Ali Adnan;  Chen, Jun Hui;  Hou, Jin Cai;  Fan, Xian Ming;  Leung, Elaine Lai Han;  Fan, Xing Xing
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/01/31
In Silico Study of the Acquired Resistance Caused by the Secondary Mutations of KRAS G12C Protein Using Long Time Molecular Dynamics Simulation and Markov State Model Analysis Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 22
Authors:  Tu, Gao;  Liu, Qing;  Qiu, Yue;  Leung, Elaine Lai Han;  Yao, Xiaojun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2023/01/31
drug resistance  KRAS G12C inhibitor  Markov state model  molecular dynamics  
Novel clinical biomarkers in blood and pleural effusion for diagnosing patients with tuberculosis distinguishing from malignant tumor Journal article
Medicine (United States), 2022,Volume: 101,Issue: 41
Authors:  Wang, Jian;  Feng, Zhe Xiang;  Ren, Tao;  Meng, Wei Yu;  Khan, Imran;  Fan, Xing Xing;  Pan, Hu Dan;  Liu, Liang;  Tang, Yi Jun;  Yao, Xiao Jun;  Li, Run Ze;  Wang, Mei Fang;  Leung, Elaine Lai Han
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/11/07
Biomarker  Cancerous  Diagnosis  Pleural Effusion  Tuberculous  
Anoikis-Associated Lung Cancer Metastasis: Mechanisms and Therapies Journal article
Cancers, 2022,Volume: 14,Issue: 19
Authors:  Wang, Jing;  Luo, Zhijie;  Lin, Lizhu;  Sui, Xinbing;  Yu, Lili;  Xu, Cong;  Zhang, Ruonan;  Zhao, Ziming;  Zhu, Qianru;  An, Bo;  Wang, Qiao;  Chen, Bi;  Leung, Elaine Lai Han;  Wu, Qibiao
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/11/07
Anoikis  Apoptosis  Lung Cancer  Molecular Mechanism Therapy  Neoplasm Metastasis  
Chelerythrine ameliorates rheumatoid arthritis by modulating the AMPK/mTOR/ULK-1 signaling pathway Journal article
Phytomedicine, 2022,Volume: 104
Authors:  Cai, Jun;  Zhang, Lu Chen;  Zhao, Ren Jie;  Pu, Li Min;  Chen, Ke Yuan;  Nasim, Ali Adnan;  Leung, Elaine Lai Han;  Fan, Xing Xing
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2023/01/30
AMPK/mTOR/ULK-1  Apoptosis  Autophagy  Chelerythrine  Rheumatoid arthritis  
Bacteria-based nanodrug for anticancer therapy Journal article
Pharmacological Research, 2022,Volume: 182
Authors:  Xie, Ya Jia;  Huang, Min;  Li, Dan;  Hou, Jin Cai;  Liang, Hai Hai;  Nasim, Ali Adnan;  Huang, Ju Min;  Xie, Chun;  Leung, Elaine Lai Han;  Fan, Xing Xing
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date：2023/01/30
Anticancer  Bacteria  Bacteriotherapy  Immunotherapy  Nanotechnology  
The key role of sphingolipid metabolism in cancer: New therapeutic targets, diagnostic and prognostic values, and anti-tumor immunotherapy resistance Journal article
Frontiers in Oncology, 2022,Volume: 12
Authors:  Li, Run Ze;  Wang, Xuan Run;  Wang, Jian;  Xie, Chun;  Wang, Xing Xia;  Pan, Hu Dan;  Meng, Wei Yu;  Liang, Tu Liang;  Li, Jia Xin;  Yan, Pei Yu;  Wu, Qi Biao;  Liu, Liang;  Yao, Xiao Jun;  Leung, Elaine Lai Han
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anticancer  cancer  enzymes  immunotherapy  sphingolipid metabolism  
Cordycepin Inhibits Triple-Negative Breast Cancer Cell Migration and Invasion by Regulating EMT-TFs SLUG, TWIST1, SNAIL1, and ZEB1 Journal article
Frontiers in Oncology, 2022,Volume: 12
Authors:  Wei, Chunli;  Khan, Md Asaduzzaman;  Du, Jiaman;  Cheng, Jingliang;  Tania, Mousumi;  Leung, Elaine Lai Han;  Fu, Junjiang
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date：2023/01/30
cancer therapeutics  cell migration and invasion  cordycepin  Slug  triple-negative breast cancer (TNBC)  Twist1