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The development of behavioral sensitization induced by a single morphine exposure in adult zebrafish (Danio rerio) Journal article
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2022,Volume: 113
Authors:  Bian, Yaqi;  Wang, Xiufen;  Liang, Jian hui;  Li, Lin;  Wu, Xue;  Tang, Benqin;  Leung, George Pak Heng;  Lee, Simon Ming Yuen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/28
Behavioral Sensitization  Drug Addiction  Morphine  Zebrafish  
Structure-Activity Relationship Studies of 4-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-6-imino-N-(naphthalen-2-yl)-1,3,5-triazin-2-amine (FPMINT) Analogues as Inhibitors of Human Equilibrative Nucleoside Transporters Journal article
Frontiers in Pharmacology, 2022,Volume: 13
Authors:  Li, Renkai;  Mak, Winston Wing Shum;  Li, Jingjing;  Zheng, Chengwen;  Shiu, Polly Ho Ting;  Seto, Sai Wang;  Lee, Simon Ming Yuen;  Leung, George Pak Heng
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
equilibrative nucleoside transporter  FPMINT  inhibitor  mechanism of action  structure-activity relationship  
The new andrographolide derivative AGS-30 induces apoptosis in human colon cancer cells by activating a ROS-dependent JNK signalling pathway Journal article
Phytomedicine, 2022,Volume: 94
Authors:  Liu, Zhuyun;  Wu, Xiaoping;  Dai, Kun;  Li, Renkai;  Zhang, Jinming;  Sheng, Dekuan;  Lee, Simon Ming Yuen;  Leung, George Pak Heng;  Zhou, Guo Chun;  Li, Jingjing
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/02/21
Andrographolide Derivative  Apoptosis  Colon Cancer  Reactive Oxygen Species  
Relaxation effect of narirutin on rat mesenteric arteries via nitric oxide release and activation of voltage-gated potassium channels Journal article
European Journal of Pharmacology, 2021,Volume: 905
Authors:  Wong, Emily Sze Wan;  Li, Rachel Wai Sum;  Li, Jingjing;  Li, Renkai;  Seto, Sai Wang;  Lee, Simon Ming Yuen;  Leung, George Pak Heng
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/12/08
Endothelium  Narirutin  Nitric Oxide  Relaxation  Voltage-gated Potassium Channels  
Amauroderma rugosum Protects PC12 Cells against 6-OHDA-Induced Neurotoxicity through Antioxidant and Antiapoptotic Effects Journal article
Oxidative Medicine and Cellular Longevity, 2021,Volume: 2021
Authors:  Li, Jingjing;  Li, Renkai;  Wu, Xiaoping;  Hoo, Ruby Lai Chong;  Lee, Simon Ming Yuen;  Cheung, Timothy Man Yau;  Ho, Bryan Siu Yin;  Leung, George Pak Heng
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2022/05/13
Dietary compound glycyrrhetinic acid suppresses tumor angiogenesis and growth by modulating antiangiogenic and proapoptotic pathways in vitro and in vivo Journal article
Journal of Nutritional Biochemistry, 2020,Volume: 77
Authors:  Li,Jingjing;  Tang,Fan;  Li,Renkai;  Chen,Zhejie;  Lee,Simon Ming Yuen;  Fu,Chaomei;  Zhang,Jinming;  Leung,George Pak Heng
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date:2021/03/01
Antiangiogenesis  Apoptosis  Dietary Compound  Glycyrrhetinic Acid  Ovarian Cancer  
AGS-30, an andrographolide derivative, suppresses tumor angiogenesis and growth in vitro and in vivo Journal article
Biochemical Pharmacology, 2020,Volume: 171
Authors:  Li,Jingjing;  Li,Feng;  Tang,Fan;  Zhang,Jinming;  Li,Renkai;  Sheng,Dekuan;  Lee,Simon Ming Yuen;  Zhou,Guo Chun;  Leung,George Pak Heng
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2021/03/01
Andrographolide Derivative  Anti-angiogenic  Colon Cancer  Vegf  
Hepatoprotective Effect of Jianpi Huoxue Formula on Nonalcoholic Fatty Liver Disease Induced by Methionine-Choline-Deficient Diet in Rat Journal article
BIOMED RESEARCH INTERNATIONAL, 2019,Volume: 2019
Authors:  Yu Feng;  Yan Chen;  Binrui Yang;  Qingping Lan;  Tao Wang;  Guozhen Cui;  Zhitao Ren;  I. Cheong Choi;  George Pak-Heng Leung;  Fenggen Yan;  Dacan Chen;  Hon Ho Yu;  Simon Ming Yuen Lee
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2020/01/16
Sichuan pepper attenuates H2O2-induced apoptosis via antioxidant activity and up-regulating heme oxygenase-1 gene expression in primary rat hepatocytes Journal article
JOURNAL OF FOOD BIOCHEMISTRY, 2017,Volume: 41,Issue: 6
Authors:  Zhang, Huan;  Zhou, Xuelin;  Wong, Marcus Ho-Yin;  Man, Ka-Yi;  Pin, Wing-Kwan;  Yeung, John Hok-Keung;  Kwan, Yiu-Wa;  Leung, George Pak-Heng;  Hoi, Pui-Man;  Lee, Simon Ming-Yuen;  Chan, Chi-On;  Mok, Daniel Kam-Wah;  Yu, Peter Hoi-Fu;  Chan, Shun-Wan
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2018/10/30
Liver  Reactive Oxygen Species  Rutaceae  Zanthoxylum Bungeanum Maxim  
Pro-angiogenic effects of Ilexsaponin A1 on human umbilical vein endothelial cells in vitro and zebrafish in vivo Journal article
PHYTOMEDICINE, 2017,Volume: 36,Page: 229-237
Authors:  Li, Jingjing;  Zhang, Jinming;  Zou, Liang;  Lee, Simon Ming-Yuen;  Yang, Cui;  Seto, Sai-Wang;  Leung, George Pak-Heng
Favorite |  | TC[WOS]:16 TC[Scopus]:16 | Submit date:2018/10/30
Ilexsaponin A1  Ilex Pubescens  Pro-angiogenesis  Zebrafish  Endothelial Cells