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Proteome-wide Identification of Off-Targets of a Potent EGFRL858R/T790MMutant Inhibitor Journal article
ACS Medicinal Chemistry Letters, 2022,Volume: 13,Issue: 2,Page: 292-297
Authors:  Lyu, Peng;  Jiang, Kaili;  Zhou, Yuee;  Hu, Jun;  Chang, Yu;  Zhang, Zhang;  Huang, Minhao;  Zhang, Zhi Min;  Ding, Ke;  Hao, Piliang;  Lin, Ligen;  Li, Zhengqiu
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/04
Bioimaging  Chemoproteomics  Egfr T790m  Nt5dc1  Target Identification  
Development and application of novel electrophilic warheads in target identification and drug discovery Journal article
Biochemical Pharmacology, 2021,Volume: 190
Authors:  Liu, Yue;  Lv, Shumin;  Peng, Lijie;  Xie, Chengliang;  Gao, Liqian;  Sun, Hongyan;  Lin, Ligen;  Ding, Ke;  Li, Zhengqiu
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/12/08
Activity-based Protein Profiling  Amino Acid Residues  Covalent Inhibitors  Electrophilic Warhead  Protein Target  
Autophagy-regulating miRNAs: potential targets for obesity and related metabolic disorders Journal article
Drug Discovery Today, 2021,Volume: 26,Issue: 6,Page: 1532-1538
Authors:  Zhang,Tian;  Linghu,Ke Gang;  Lou,Ruohan;  Li,Zhengqiu;  Liu,Jingxin;  Li,Rongsong;  Qin,Zheng Hong;  Guo,Bing;  Lin,Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/03/01
Quantitative Proteomics Reveals Cellular Off-Targets of a DDR1 Inhibitor Journal article
ACS Medicinal Chemistry Letters, 2020,Volume: 11,Issue: 4,Page: 535-540
Authors:  Xu,Jiaqian;  Zhang,Zhang;  Lin,Ligen;  Sun,Hongyan;  White,Lorenzo V.;  Ding,Ke;  Li,Zhengqiu
Favorite |  | TC[WOS]:6 TC[Scopus]:6 | Submit date:2021/03/01
Bioimaging  Chemoproteomics  Ddr1  Photoaffinity Labeling  Target Identification  
α-Mangostin remodels visceral adipose tissue inflammation to ameliorate age-related metabolic disorders in mice Journal article
Aging, 2019,Volume: 11,Issue: 23,Page: 11084-11110
Authors:  Li,Dan;  Liu,Qianyu;  Lu,Xiuqiang;  Li,Zhengqiu;  Wang,Chunming;  Leung,Chung Hang;  Wang,Yitao;  Peng,Cheng;  Lin,Ligen
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date:2021/03/01
Adipose Tissue Inflammation  Adiposity  Aging  Macrophage  Α-mangostin  
Affinity-Based Protein Profiling Reveals Cellular Targets of Photoreactive Anticancer Inhibitors Journal article
ACS Chemical Biology, 2019,Volume: 14,Issue: 12,Page: 2546-2552
Authors:  Ma,Nan;  Zhang,Zhi Min;  Lee,Jun Seok;  Cheng,Ke;  Lin,Ligen;  Zhang,Dong Mei;  Hao,Piliang;  Ding,Ke;  Ye,Wen Cai;  Li,Zhengqiu
Favorite |  | TC[WOS]:12 TC[Scopus]:10 | Submit date:2021/03/01
Leucine-zipper and sterile-α motif kinase (ZAK): A potential target for drug discovery Journal article
Current Medicinal Chemistry, 2016,Volume: 23,Issue: 33,Page: 3801-3812
Authors:  Chang,Yu;  Zhang,Qingwen;  Li,Zhengqiu;  Ding,Ke;  Lu,Xiaoyun
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/02
Cancer  Cardiac Hypertrophy  Inflammation  Mapk  Mlks  Zak