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Acetyltanshinone IIA reduces the synthesis of cell cycle-related proteins by degrading p70S6K and subsequently inhibits drug-resistant lung cancer cell growth
Journal article
Pharmacological Research, 2022,Volume: 179
Authors:
Huang, Bin
;
Hao, Meng
;
Li, Chuwen
;
Luo, Kathy Qian
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
Acetyltanshinone IIA
Afatinib (PubChem CID: 10184653)
Aurora kinase A
Drug-resistant lung cancer
EGFR
Erlotinib (PubChem CID: 176870)
LY294002 (PubChem CID: 3973)
MLN8237 (PubChem CID: 24771867)
Osimertinib (PubChem CID: 71496458)
P70S6K
PF-4708671 (PubChem CID: 51371303)
Rapamycin (PubChem CID: 5284616)
Tanshinone IIA (PubChem CID: 164676)
Zebrafish: A Promising Model for Evaluating the Toxicity of Carbon Dot-Based Nanomaterials
Journal article
ACS Applied Materials and Interfaces, 2020,Volume: 12,Issue: 43,Page: 49012-49020
Authors:
Liu,Wei
;
Huang,Gang
;
Su,Xiaoying
;
Li,Siyi
;
Wang,Qun
;
Zhao,Yuying
;
Liu,Yao
;
Luo,Jingshan
;
Li,Ye
;
Li,Chuwen
;
Yuan,Dongsheng
;
Hong,Honghai
;
Chen,Xiaojia
;
Chen,Tongkai
Favorite
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TC[WOS]:
13
TC[Scopus]:
11
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Submit date:2021/03/02
Carbon Nanomaterials
Developmental Neurotoxicity
Dopamine
Nanotoxicology
Zebrafish (Danio Rerio)
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome
Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:
Zhou,Hefeng
;
Li,Shengnan
;
Li,Chuwen
;
Yang,Xuanjun
;
Li,Haitao
;
Zhong,Hanbing
;
Lu,Jia Hong
;
Lee,Simon Ming Yuen
Favorite
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TC[WOS]:
6
TC[Scopus]:
6
|
Submit date:2021/03/01
Parkinson's Disease
Α-synuclein
Degradation
Proteasome
Neuroprotection
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo
Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:
Zhou,Hefeng
;
Shao,Min
;
Yang,Xuanjun
;
Li,Chuwen
;
Cui,Guozhen
;
Gao,Cheng
;
Di,Lijun
;
Zhong,Hanbing
;
Wang,Yuqiang
;
Zhang,Zaijun
;
Lee,Simon Ming Yuen
Favorite
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TC[WOS]:
10
TC[Scopus]:
9
|
Submit date:2021/03/01
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models
Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:
Zhou,Hefeng
;
Shao,Min
;
Guo,Baojian
;
Li,Chuwen
;
Lu,Yucong
;
Yang,Xuanjun
;
ShengnanLi,
;
Li,Haitao
;
Zhu,Qi
;
Zhong,Hanbing
;
Wang,Yuqiang
;
Zhang,Zaijun
;
Lu,Jiahong
;
Lee,Simon Ming Yuen
Favorite
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TC[WOS]:
13
TC[Scopus]:
14
|
Submit date:2021/03/01
Degradation
Lmp7
Parkinson’s Disease
Proteasome Activity
Α-synuclein
Neuroprotective Effects of BHDPC, a Novel Neuroprotectant, on Experimental Stroke by Modulating Microglia Polarization
Journal article
ACS CHEMICAL NEUROSCIENCE, 2019,Volume: 10,Issue: 5,Page: 2434-2449
Authors:
Chuwen Li
;
Yaqi Bian
;
Yu Feng
;
Fan Tang
;
Liang Wang
;
Maggie Pui Man Hoi
;
Dan Ma
;
Chao Zhao
;
Simon Ming Yuen Lee
Favorite
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TC[WOS]:
19
TC[Scopus]:
19
|
Submit date:2020/01/16
Bhdpc
Ischemic Stroke
Microglia
Nf-κb
Creb
Pka
Suppressive effects of the supercritical-carbon dioxide fluid extract of Chrysanthemum indicum on chronic unpredictable mild stress-induced depressive-like behavior in mice
Journal article
FOOD & FUNCTION, 2019,Volume: 10,Issue: 2,Page: 1212-1224
Authors:
Xiaoli Wu
;
Benqin Tang
;
Xian Liao
;
Ziren Su
;
Simon Ming-Yuen Lee
;
Yefeng Cai
;
Chuwen Li
Favorite
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TC[WOS]:
16
TC[Scopus]:
14
|
Submit date:2020/01/16
Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction
Journal article
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018,Volume: 66,Issue: 31,Page: 8307-8318
Authors:
Li, Chuwen
;
Tang, Benqin
;
Feng, Yu
;
Tang, Fan
;
Hoi, Maggie Pui-Man
;
Su, Ziren
;
Lee, Simon Ming-Yuen
Favorite
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TC[WOS]:
33
TC[Scopus]:
37
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Submit date:2018/10/31
Pinostrobin
Parkinson's Disease
Neurotoxin
Nrf2
Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation
Journal article
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:
Li, Chuwen
;
Chen, Tongkai
;
Zhou, Hefeng
;
Zhang, Chao
;
Feng, Yu
;
Tang, Fan
;
Hoi, Maggie Pui-Man
;
He, Chengwei
;
Zheng, Ying
;
Lee, Simon Ming-Yuen
Favorite
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TC[WOS]:
24
TC[Scopus]:
27
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Submit date:2018/10/30
Schisantherin a
Neuroinflammation
Microglia
Nrf2
Nf-kappa b
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB
Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:
Li, Chuwen
;
Chen, Tongkai
;
Zhou, Hefeng
;
Feng, Yu
;
Hoi, Maggie P. M.
;
Ma, Dan
;
Zhao, Chao
;
Zheng, Ying
;
Lee, Simon M. Y.
Favorite
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TC[WOS]:
11
TC[Scopus]:
13
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Submit date:2018/10/30
Bhdpc
Neuroinflammation
Microglia
Nf-kappa b
Creb
Pka