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Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy Journal article
Chinese Medicine (United Kingdom), 2022,Volume: 17,Issue: 1
Authors:  Zhang, Shuang;  Dong, Yu;  Chen, Xiuping;  Tan, Chris Soon Heng;  Li, Min;  Miao, Kai;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
Apoptosis  Autophagy Inhibition  Irinotecan  Lysosome  Sn-38  Toosendanin  Triple-negative Breast Cancer  
Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 Journal article
Acta Pharmacologica Sinica, 2022,Volume: 43,Issue: 5,Page: 1251-1263
Authors:  Yang, Chuan bin;  Liu, Jia;  Tong, Benjamin Chun Kit;  Wang, Zi ying;  Zhu, Zhou;  Su, Cheng fu;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Wu, Jia xi;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Huang, Shi ying;  Cheung, King ho;  Song, Ju xian;  Tan, Jie qiong;  Lu, Jia hong;  Li, Min
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15-deoxy-∆-12,14-prostaglandin J2 (15d-pgJ2)  Apoptosis  Atf4  Autophagy And Lysosome Biogenesis  Er Stress  Transcriptional Factor Eb (tfEb)  
Mechanistic Insights into Selective Autophagy Subtypes in Alzheimer’s Disease Journal article
International Journal of Molecular Sciences, 2022,Volume: 23,Issue: 7
Authors:  Guan, Xinjie;  Iyaswamy, Ashok;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Su, Chengfu;  Zhu, Zhou;  Liu, Jia;  Kan, Yuxuan;  Cheung, King Ho;  Lu, Jiahong;  Tan, Jieqiong;  Li, Min
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Aggrephagy  Alzheimer’s Disease  Lipophagy  Lysophagy  Mitophagy  Nucleophagy  Pexophagy  Reticulophagy  Ribophagy  Selective Autophagy  
Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 3,Page: 624-642
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Zhu, Zhou;  Su, Chengfu;  Liu, Jia;  Song, Juxian;  Lu, Jia Hong;  Tan, Jieqiong;  Pan, Weidong;  Li, Min;  Cheung, King Ho
Favorite |  | TC[WOS]:5 TC[Scopus]:7 | Submit date:2022/05/17
Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2  
Emerging roles of NRBF2/PI3KC3 axis in maintaining homeostasis of brain and guts Journal article
Neural Regeneration Research, 2022,Volume: 17,Issue: 2,Page: 323-324
Authors:  Wu, Ming Yue;  Cai, Cui Zan;  Yang, Chuanbin;  Yue, Zhenyu;  Chen, Ye;  Bian, Zhao Xiang;  Li, Min;  Lu, Jia Hong
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Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition Journal article
Phytomedicine, 2022,Volume: 96
Authors:  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Senapati, Sanjib;  Malampati, Sandeep;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Guan, Xin Jie;  Tong, Benjamin Chun Kit;  Cheung, King Ho;  Tan, Jie Qiong;  Lu, Jia Hong;  Durairajan, Siva Sundara Kumar;  Song, Ju Xian;  Li, Min
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3xtg-ad Mice  Alzheimer's Disease  Hdac6  P301s-tau Mice  Phospho-tau  Protopine  
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Journal article
Acta Pharmacologica Sinica, 2022
Authors:  Zhu, Zhou;  Liu, Liang feng;  Su, Cheng fu;  Liu, Jia;  Tong, Benjamin Chun Kit;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Guan, Xin jie;  Kan, Yu xuan;  Xie, Wen jian;  Zhao, Chen liang;  Cheung, King ho;  Lu, Jia hong;  Tan, Jie qiong;  Zhang, Hong jie;  Song, Ju xian;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
Autophagy  Corynoxine b  Dopaminergic Neuron  Mpp++++  Oxindole Alkaloid  Parkinson’s Disease  Pi3p  Pik3c3 Complex  
Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models Journal article
Theranostics, 2022,Volume: 12,Issue: 4,Page: 1738-1755
Authors:  Cai, Cui Zan;  Zhuang, Xu Xu;  Zhu, Qi;  Wu, Ming Yue;  Su, Huanxing;  Wang, Xiao Jin;  Iyaswamy, Ashok;  Yue, Zhenyu;  Wang, Qian;  Zhang, Bin;  Xue, Yu;  Tan, Jieqiong;  Li, Min;  He, Huanhuan;  Lu, Jia Hong
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Alzheimer's Disease  Autophagy    Ccz1-mon1a  Rab7  
Pharmacological insights into autophagy modulation in autoimmune diseases Journal article
Acta Pharmaceutica Sinica B, 2021,Volume: 11,Issue: 11,Page: 3364-3378
Authors:  Wu, Ming Yue;  Wang, Er Jin;  Feng, Du;  Li, Min;  Ye, Richard D.;  Lu, Jia Hong
Favorite |  | TC[WOS]:2 TC[Scopus]:1 | Submit date:2021/12/08
Autoimmune disease  Autophagy  Autophagy inducer  Autophagy inhibitor  Experimental autoimmune encephalomyelitis  Inflammatory bowel disease  Rheumatoid arthritis  Systemic lupus erythematosus