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Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets Journal article
Biomolecules, 2022,Volume: 12,Issue: 3
Authors:  Pradhan, Geetali;  Lee, Jong Han;  Wu, Chia Shan;  Wang, Hongying;  Lin, Ligen;  Donti, Taraka;  Graham, Brett H.;  Rajan, Arun S.;  Balasubramanyam, Ashok;  Samson, Susan L.;  Guo, Shaodong;  Sun, Yuxiang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/28
Glucose Transporter 2 (Glut2)  Glucose-stimulated Insulin Secretion (Gsis)  Growth Hormone Secretagogue Receptor (Ghs-r)  Insulin  Islets  Pancreatic And Duodenal Homeobox 1 (Pdx1)  
Proteome-wide Identification of Off-Targets of a Potent EGFRL858R/T790MMutant Inhibitor Journal article
ACS Medicinal Chemistry Letters, 2022,Volume: 13,Issue: 2,Page: 292-297
Authors:  Lyu, Peng;  Jiang, Kaili;  Zhou, Yuee;  Hu, Jun;  Chang, Yu;  Zhang, Zhang;  Huang, Minhao;  Zhang, Zhi Min;  Ding, Ke;  Hao, Piliang;  Lin, Ligen;  Li, Zhengqiu
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/04
Bioimaging  Chemoproteomics  Egfr T790m  Nt5dc1  Target Identification  
The role of irisin in metabolic flexibility: Beyond adipose tissue browning Journal article
Drug Discovery Today, 2022
Authors:  Shen, Shengnan;  Liao, Qiwen;  Chen, Xiuping;  Peng, Cheng;  Lin, Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
FNDC5  Insulin sensitivity  Irisin  Metabolic flexibility  Obesity  Skeletal muscle  
Macrocephatriolides A and B: Two Guaianolide Trimers from Ainsliaea macrocephala as PTP1B Inhibitors and Insulin Sensitizers Journal article
Journal of Organic Chemistry, 2021,Volume: 86,Issue: 24,Page: 17782-17789
Authors:  Ren, Yong Mei;  Zhang, Rui;  Feng, Zheling;  Ke, Chang Qiang;  Yao, Sheng;  Tang, Chunping;  Lin, Ligen;  Ye, Yang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/01/14
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy Journal article
Chinese Medicine (United Kingdom), 2021,Volume: 16,Issue: 1
Authors:  Liu, Jingxin;  Zhang, Tian;  Zhu, Jianzhong;  Ruan, Shuangchen;  Li, Rongsong;  Guo, Bing;  Lin, Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2021/12/08
Hepatocytes  Honokiol  Lipid Accumulation  Lipolysis  Lipophagy  Sirt3  
Guaianolides from Artemisia codonocephala suppress interleukine-1β secretion in macrophages Journal article
Phytochemistry, 2021,Volume: 192
Authors:  Wang, Qiaoqiao;  Zhang, Tian;  Ke, Chang Qiang;  Tang, Chunping;  Yao, Sheng;  Lin, Ligen;  Ye, Yang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Anti-inflammation  Artemisia Codonocephala  Asteraceae  Guaianolides  Il-1β  Nlrp3  
Caesalpinaxin, a cassane-type diterpenoid with a 21-carbon core skeleton from the seeds of Caesalpinia minax possessing pro-angiogenetic property Journal article
Bioorganic Chemistry, 2021,Volume: 117
Authors:  Lou, Ruohan;  Xu, Fan;  Xu, Yunshao;  Chen, Jiali;  Feng, Zheling;  Gan, Lishe;  Lin, Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Angiogenesis  Caesalpinaxin  Cassalpinia Minax  Ecd  Fabaceae  
A small molecule HIF-1α stabilizer that accelerates diabetic wound healing Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Li, Guodong;  Ko, Chung Nga;  Li, Dan;  Yang, Chao;  Wang, Wanhe;  Yang, Guan Jun;  Di Primo, Carmelo;  Wong, Vincent Kam Wai;  Xiang, Yaozu;  Lin, Ligen;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:7 TC[Scopus]:13 | Submit date:2021/12/09
Anti-hyperglycemic effects of refined fractions from cyclocarya paliurus leaves on streptozotocin-induced diabetic mice Journal article
Molecules, 2021,Volume: 26,Issue: 22
Authors:  Feng, Zheling;  Fang, Zhujun;  Chen, Cheng;  Vong, Chi Teng;  Chen, Jiali;  Lou, Ruohan;  Hoi, Maggie Pui Man;  Gan, Lishe;  Lin, Ligen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Anti-hyperglycemia  Cyclocarya Paliurus  Flavonoids  Polysaccharides  Triterpenoids  
Therapeutic potential of isobavachalcone, a natural flavonoid, in murine experimental colitis by inhibiting NF-κB p65 Journal article
Phytotherapy Research, 2021,Volume: 35,Issue: 10,Page: 5861-5870
Authors:  Zhou, Yishan;  Zhong, Bingling;  Min, Xiangjing;  Hou, Ying;  Lin, Ligen;  Wu, Qin;  Shi, Jingshan;  Chen, Xiuping
Favorite |  | TC[WOS]:1 TC[Scopus]:3 | Submit date:2021/12/08
Inflammation  Isobavachalcone  Nf-κb P65  Ulcerative Colitis