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Brij-functionalized chitosan nanocarrier system enhances the intestinal permeability of P-glycoprotein substrate-like drugs Journal article
Carbohydrate Polymers, 2021,Volume: 266
Authors:  Xiong, Wei;  Xiong, Shi Hang;  Chen, Qi Ling;  Linghu, Ke Gang;  Zhao, Guan Ding;  Chu, John M.T.;  Wong, Gordon T.C.;  Li, Juan;  Hu, Yuan Jia;  Wang, Yi Tao;  Yu, Hua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/09/13
Berberine  Brij-grafted-chitosan  Diabetic Kidney Disease  Oral Nanocarrier  P-glycoprotein  
Botany, traditional use, phytochemistry, pharmacology and toxicology of Sigesbeckiae Herba (Xixiancao): a review Journal article
Phytochemistry Reviews, 2021
Authors:  Tao,Hong Xun;  Zhao,Guan Ding;  Linghu,Ke Gang;  Xiong,Wei;  Sang,Wei;  Peng,Yu;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:6 TC[Scopus]:4 | Submit date：2021/03/02
Pharmacology  Phytochemistry  Sigesbeckiae Herba  Toxicology  Traditional Use  
Autophagy-regulating miRNAs: potential targets for obesity and related metabolic disorders Journal article
Drug Discovery Today, 2021,Volume: 26,Issue: 6,Page: 1532-1538
Authors:  Zhang,Tian;  Linghu,Ke Gang;  Lou,Ruohan;  Li,Zhengqiu;  Liu,Jingxin;  Li,Rongsong;  Qin,Zheng Hong;  Guo,Bing;  Lin,Ligen
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/03/01
Small molecule-driven SIRT3-autophagy-mediated NLRP3 inflammasome inhibition ameliorates inflammatory crosstalk between macrophages and adipocytes Journal article
British Journal of Pharmacology, 2020,Volume: 177,Issue: 20,Page: 4645-4665
Authors:  Zhang,Tian;  Fang,Zhujun;  Linghu,Ke Gang;  Liu,Jingxin;  Gan,Lishe;  Lin,Ligen
Favorite |  | TC[WOS]:19 TC[Scopus]:18 | Submit date：2021/03/01
Adipocytes  Adipose Tissue Inflammation  Autophagy  Cycloartane Triterpenoid  Il-1β, Macrophages  Macrophages  Nlrp3 Inflammasome  
Interactions of antithrombotic herbal medicines with Western cardiovascular drugs Journal article
Pharmacological Research, 2020,Volume: 159
Authors:  Zuo,Hua Li;  Linghu,Ke Gang;  Wang,Ya Li;  Liu,Kun Meng;  Gao,Yan;  Yu,Hua;  Yang,Feng Qing;  Hu,Yuan Jia
Favorite |  | TC[WOS]:9 TC[Scopus]:9 | Submit date：2021/03/01
Antithrombotic Herbal Medicine  Western Drugs  Network Pharmacology  Cardiovascular Disease  Herb-drug Interaction  
Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation Journal article
Frontiers in Pharmacology, 2020,Volume: 11
Authors:  Linghu,Ke Gang;  Xiong,Shi Hang;  Zhao,Guan Ding;  Zhang,Tian;  Xiong,Wei;  Zhao,Mingming;  Shen,Xiang Chun;  Xu,Wei;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/03/02
Inflammation  Mh7a  Rheumatoid Arthritis  Sigesbeckia Orientalisl  Sw982  Synovial Hyperplasia  
Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation Journal article
Chinese Medicine (United Kingdom), 2020,Volume: 15,Issue: 1
Authors:  Ma,Qiu Shuo;  Linghu,Ke Gang;  Zhang,Tian;  Zhao,Guan Ding;  Xiong,Wei;  Xiong,Shi Hang;  Zhao,Mingming;  Xu,Wei;  Yu,Juan;  Yu,Hua
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/03/02
Inflammation  Nuclear Transcription Factor-kappa b  Rheumnnatoid Arthritis  Sigesbeckia Glabrescens Makino  Sw982  Synovial Hyperplasia  
Comprehensive comparison on the anti-inflammatory effects of three species of Sigesbeckia plants based on NF-κB and MAPKs signal pathways in vitro Journal article
Journal of Ethnopharmacology, 2020,Volume: 250
Authors:  Linghu,Ke Gang;  Zhao,Guan Ding;  Xiong,Wei;  Sang,Wei;  Xiong,Shi Hang;  Tse,Anfernee Kai Wing;  Hu,Yuanjia;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date：2021/03/01
Anti-inflammation  Mapks  Nf-κb  Sigesbeckia Glabrescens Makino  Sigesbeckia OrientaL.s L.  Sigesbeckia Pubescens Makino  
Leocarpinolide B attenuates LPS-induced inflammation on RAW264.7 macrophages by mediating NF-κB and Nrf2 pathways Journal article
European Journal of Pharmacology, 2020,Volume: 868
Authors:  Linghu,Ke Gang;  Ma,Qiu Shuo;  Zhao,Guan Ding;  Xiong,Wei;  Lin,Ligen;  Zhang,Qing Wen;  Bian,Zhaoxiang;  Wang,Yitao;  Yu,Hua
Favorite |  | TC[WOS]:9 TC[Scopus]:9 | Submit date：2021/03/01
Leocarpinolide b  Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)  Nuclear Transcription Factor-kappa b (Nf-κb)  Rheumatoid Arthritis (Ra)  Sigesbeckiae Herba (Sh)  
Dual-functional Brij-S20-modified nanocrystal formulation enhances the intestinal transport and oral bioavailability of berberine Journal article
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018,Volume: 13,Page: 3781-3793
Authors:  Xiong, Wei;  Sang, Wei;  Linghu, Ke Gang;  Zhong, Zhang Feng;  Cheang, Wai San;  Li, Juan;  Hu, Yuan Jia;  Yu, Hua;  Wang, Yi Tao
Favorite |  | TC[WOS]:18 TC[Scopus]:18 | Submit date：2018/10/30
Berberine  Poor Water Solubility  Pgp-mediated Drug Efflux  Brij  Nanocrystals