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A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer
Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:
Xinhua Zhou
;
Anqi Wang
;
Liang Wang
;
Jianhua Yin
;
Li Wang
;
Lijun Di
;
Maggie Pui-Man Hoi
;
Luchen Shan
;
Xu Wu
;
Yuqiang Wang
Favorite
|
|
TC[WOS]:
3
TC[Scopus]:
4
|
Submit date:2020/05/21
Danshensu
Tetramethylpyrazine
Breast Cancer
Resistance
Glycolysis
P-glycoprotein
A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells
Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019,Volume: 120,Issue: 4,Page: 5913-5922
Authors:
Ying Zhang
;
Hongkuan Deng
;
Hefeng Zhou
;
Yucong Lu
;
Luchen Shan
;
Simon Ming‐Yuen Lee
;
Guozhen Cui
Favorite
|
|
TC[WOS]:
7
TC[Scopus]:
7
|
Submit date:2020/01/16
Antitumor
Biotin-conjugated Adtm Analog (Baa)
Cardioprotection
Cardiotoxicity
Doxorubicin (Dox)
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor
Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:
Hu, Shengquan
;
Hu, Huihui
;
Mak, Shinghung
;
Cui, Guozhen
;
Lee, Mingyuen
;
Shan, Luchen
;
Wang, Yuqiang
;
Lin, Huangquan
;
Zhang, Zaijun
;
Han, Yifan
Favorite
|
|
TC[WOS]:
8
TC[Scopus]:
9
|
Submit date:2018/10/30
Alzheimer's disease
tetramethylpyrazine derivative
NMDA receptor
neuroprotection
oxidative stress
GSK3 beta
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways
Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:
Tang, Fan
;
Zhou, Xinhua
;
Wang, Liang
;
Shan, Luchen
;
Li, Chuwen
;
Zhou, Hefeng
;
Lee, Simon Ming-Yuen
;
Hoi, Maggie Pui-Man
Favorite
|
|
TC[WOS]:
23
TC[Scopus]:
21
|
Submit date:2018/10/30
Cardioprotection
Anti-oxidative Stress
Anti-apoptosis
Autophagy Regulation
Zebrafish Cardiotoxicity
H9c2 Cardiomyocytes
A New Danshensu Derivative Protects Against 6-Hydroxydopamine-Induced Neurotoxicity in Vitro and in Vivo
Journal article
American Journal of Chinese Medicine, 2016,Volume: 44,Issue: 7,Page: 1349-1361
Authors:
Guozhen Cui
;
Luchen Shan
;
Yang Chen
;
Hefeng Zhou
;
Yuqiang Wang
;
Simon Ming-Yuen Lee
Favorite
|
|
TC[WOS]:
4
TC[Scopus]:
4
|
Submit date:2018/11/06
Anti-inflammation
Anti-oxidation
Danshensu Derivative
Neuroprotection
A Novel Danshensu Derivative Prevents Cardiac Dysfunction and Improves the Chemotherapeutic Efficacy of Doxorubicin in Breast Cancer Cells
Journal article
Journal of Cellular Biochemistry, 2016,Volume: 117,Issue: 1,Page: 94-105
Authors:
Liang Wang
;
Xiaojing Zhang
;
Judy Yuet‐Wa Chan
;
Luchen Shan
;
Guozhen Cui
;
Qingbin Cui
;
Yingfei Wang
;
Jingjing Li
;
Huanxian Chen
;
Qingwen Zhang
;
Pei Yu
;
Yifan Han
;
Yuqiang Wang
;
Simon Ming‐Yuen Lee
Favorite
|
|
TC[WOS]:
20
TC[Scopus]:
22
|
Submit date:2018/11/06
Breast Cancer
Cardiotoxicity
Doxorubicin
Mitochondrial Biogenesis
Identification of disulfide isomerase ERp57 as a target for small molecule cardioprotective agents
Journal article
RSC Advances, 2015,Volume: 5,Issue: 91,Page: 74605-74610
Authors:
Guozhen Cui
;
Luchen Shan
;
Ivan Keung Chu
;
Guohui Li
;
George Pak Heng Leung
;
Yuqiang Wang
;
Yiu Wa KWAN
;
Shun Wan CHAN
;
Maggie Pui Man Hoi
;
Simon Ming Yuen Lee
Favorite
|
|
TC[WOS]:
9
TC[Scopus]:
10
|
Submit date:2018/11/06
Synthesis and relationship of stability and biological activity of new DSS and TMP conjugates
Journal article
MedChemComm, 2015,Volume: 6,Issue: 4,Page: 586-591
Authors:
Yewei Sun
;
Zicheng Tan
;
Zhibin Liang
;
Liang Wang
;
Luchen Shan
;
Pei Yu
;
Simon MingYuen Lee
;
Yuqiang Wang
Favorite
|
|
TC[WOS]:
3
TC[Scopus]:
4
|
Submit date:2018/11/06
Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy
Journal article
Scientific Reports, 2015,Volume: 5
Authors:
Guozhen Cui
;
Luchen Shan
;
Lin Guo
;
Ivan Keung Chu
;
Guohui Li
;
Quan Quan
;
Yun Zhao
;
Cheong Meng Chong
;
Zaijun Zhang
;
Pei Yu
;
Maggie Pui Man Hoi
;
Yewei Sun
;
Yuqiang Wang
;
Simon MingYuen Lee
Favorite
|
|
TC[WOS]:
0
TC[Scopus]:
14
|
Submit date:2018/10/30