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A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer
Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:
Xinhua Zhou
;
Anqi Wang
;
Liang Wang
;
Jianhua Yin
;
Li Wang
;
Lijun Di
;
Maggie Pui-Man Hoi
;
Luchen Shan
;
Xu Wu
;
Yuqiang Wang
Favorite
|
|
TC[WOS]:
13
TC[Scopus]:
13
|
Submit date:2020/05/21
Danshensu
Tetramethylpyrazine
Breast Cancer
Resistance
Glycolysis
P-glycoprotein
A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells
Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019,Volume: 120,Issue: 4,Page: 5913-5922
Authors:
Ying Zhang
;
Hongkuan Deng
;
Hefeng Zhou
;
Yucong Lu
;
Luchen Shan
;
Simon Ming‐Yuen Lee
;
Guozhen Cui
Favorite
|
|
TC[WOS]:
10
TC[Scopus]:
11
|
Submit date:2020/01/16
Antitumor
Biotin-conjugated Adtm Analog (Baa)
Cardioprotection
Cardiotoxicity
Doxorubicin (Dox)
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor
Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:
Hu, Shengquan
;
Hu, Huihui
;
Mak, Shinghung
;
Cui, Guozhen
;
Lee, Mingyuen
;
Shan, Luchen
;
Wang, Yuqiang
;
Lin, Huangquan
;
Zhang, Zaijun
;
Han, Yifan
Favorite
|
|
TC[WOS]:
13
TC[Scopus]:
16
|
Submit date:2018/10/30
Alzheimer's Disease
Tetramethylpyrazine Derivative
Nmda Receptor
Neuroprotection
Oxidative Stress
Gsk3 Beta
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways
Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:
Tang, Fan
;
Zhou, Xinhua
;
Wang, Liang
;
Shan, Luchen
;
Li, Chuwen
;
Zhou, Hefeng
;
Lee, Simon Ming-Yuen
;
Hoi, Maggie Pui-Man
Favorite
|
|
TC[WOS]:
29
TC[Scopus]:
28
|
Submit date:2018/10/30
Cardioprotection
Anti-oxidative Stress
Anti-apoptosis
Autophagy Regulation
Zebrafish Cardiotoxicity
H9c2 Cardiomyocytes
A New Danshensu Derivative Protects Against 6-Hydroxydopamine-Induced Neurotoxicity in Vitro and in Vivo
Journal article
American Journal of Chinese Medicine, 2016,Volume: 44,Issue: 7,Page: 1349-1361
Authors:
Guozhen Cui
;
Luchen Shan
;
Yang Chen
;
Hefeng Zhou
;
Yuqiang Wang
;
Simon Ming-Yuen Lee
Favorite
|
|
TC[WOS]:
9
TC[Scopus]:
9
|
Submit date:2018/11/06
Anti-inflammation
Anti-oxidation
Danshensu Derivative
Neuroprotection
A novel agent enhances the chemotherapeutic efficacy of doxorubicin in MCF-7 breast cancer cells
Journal article
Frontiers in Pharmacology, 2016,Volume: 7,Issue: AUG
Authors:
Liang Wang
;
Judy Y. Chan
;
Xinhua Zhou
;
Guozhen Cui
;
Zhixiang Yan
;
Li Wang
;
Ru Yan
;
Lijun Di
;
Yuqiang Wang
;
Maggie P. Hoi
;
Luchen Shan
;
Simon M. Lee
Favorite
|
|
TC[WOS]:
12
TC[Scopus]:
15
|
Submit date:2018/11/06
Breast Cancer
Danshensu
Doxorubicin
Glycolysis
Grp78 Protein
Tetramethylpyrazine
A novel agent exerts antitumor activity in breast cancer cells by targeting mitochondrial complex II
Journal article
Oncotarget, 2016,Volume: 7,Issue: 22,Page: 32054-32064
Authors:
Liang Wang
;
Xiaojing Zhang
;
Guozhen Cui
;
Judy Yuet-Wa Chan
;
Li Wang
;
Chuwen Li
;
Luchen Shan
;
Changjiang Xu
;
Qingwen Zhang
;
Yuqiang Wang
;
Lijun Di
;
Simon Ming-Yuen Lee
Favorite
|
|
TC[WOS]:
28
TC[Scopus]:
33
|
Submit date:2018/11/06
Breast Cancer
Danshensu
Mitochondrial Complex Ii
Reactive Oxygen Species
Tetramethylpyrazine
Relaxation effect of a novel Danshensu/tetramethylpyrazine derivative on rat mesenteric arteries
Journal article
European Journal of Pharmacology, 2015,Volume: 761,Page: 153-160
Authors:
Rachel Wai-Sum Li
;
C. Yang
;
Luchen Shan
;
Zaijun Zhang
;
Yuqiang Wang
;
Y.W. Kwan
;
Simon M.Y. Lee
;
Maggie P.M. Hoi
;
S.W. Chan
;
Alex Chun Cheung
;
K.H. Cheung
;
George P.H. Leung
Favorite
|
|
TC[WOS]:
16
TC[Scopus]:
16
|
Submit date:2018/11/06
Calcium Channel
Danshensu Tetramethylpyrazine
Mesenteric Artery
Relaxation
Identification of disulfide isomerase ERp57 as a target for small molecule cardioprotective agents
Journal article
RSC Advances, 2015,Volume: 5,Issue: 91,Page: 74605-74610
Authors:
Guozhen Cui
;
Luchen Shan
;
Ivan Keung Chu
;
Guohui Li
;
George Pak Heng Leung
;
Yuqiang Wang
;
Yiu Wa KWAN
;
Shun Wan CHAN
;
Maggie Pui Man Hoi
;
Simon Ming Yuen Lee
Favorite
|
|
TC[WOS]:
11
TC[Scopus]:
14
|
Submit date:2018/11/06
A Novel Danshensu Derivative Prevents Cardiac Dysfunction and Improves the Chemotherapeutic Efficacy of Doxorubicin in Breast Cancer Cells
Journal article
Journal of Cellular Biochemistry, 2015,Volume: 117,Issue: 1,Page: 94-105
Authors:
Liang Wang
;
Xiaojing Zhang
;
Judy Yuet‐Wa Chan
;
Luchen Shan
;
Guozhen Cui
;
Qingbin Cui
;
Yingfei Wang
;
Jingjing Li
;
Huanxian Chen
;
Qingwen Zhang
;
Pei Yu
;
Yifan Han
;
Yuqiang Wang
;
Simon Ming‐Yuen Lee
Favorite
|
|
TC[WOS]:
25
TC[Scopus]:
27
|
Submit date:2018/11/06
Breast Cancer
Cardiotoxicity
Doxorubicin
Mitochondrial Biogenesis