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Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy Journal article
Chinese Medicine, 2022,Volume: 17,Issue: 1
Authors:  Zhang, Shuang;  Dong, Yu;  Chen, Xiuping;  Tan, Chris Soon Heng;  Li, Min;  Miao, Kai;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/31
Apoptosis  Autophagy Inhibition  Irinotecan  Lysosome  Sn-38  Toosendanin  Triple-negative Breast Cancer  
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 Journal article
Acta Pharmacologica Sinica, 2022,Volume: 43,Issue: 5,Page: 1251-1263
Authors:  Yang, Chuan bin;  Liu, Jia;  Tong, Benjamin Chun Kit;  Wang, Zi ying;  Zhu, Zhou;  Su, Cheng fu;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Wu, Jia xi;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Huang, Shi ying;  Cheung, King ho;  Song, Ju xian;  Tan, Jie qiong;  Lu, Jia hong;  Li, Min
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2022/05/13
15-deoxy-∆-12,14-prostaglandin J2 (15d-pgJ2)  Apoptosis  Atf4  Autophagy And Lysosome Biogenesis  Er Stress  Transcriptional Factor Eb (tfEb)  
Friend or Foe? Implication of the autophagy-lysosome pathway in SARS-CoV-2 infection and COVID-19 Journal article
International Journal of Biological Sciences, 2022,Volume: 18,Issue: 12,Page: 4690-4703
Authors:  He, Weifeng;  Gao, Yuan;  Zhou, Jing;  Shi, Yi;  Xia, Dajing;  Shen, Han Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/05
Autophagy  Clinical Trials  Covid-19  Lysosome  Sars-cov-2  Therapeutics  
Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans Journal article
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2021,Volume: 1867,Issue: 10
Authors:  Huang, Xiaobing;  Wang, Changliang;  Chen, Liang;  Zhang, Tianjiao;  Leung, Ka Lai;  Wong, Garry
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/08
Amyloid β  Lewy Body Dementia  Lipid Metabolism  Lysosome Function  Α-synuclein  
Garcinone E blocks autophagy through lysosomal functional destruction in ovarian cancer cells Journal article
World Journal of Traditional Chinese Medicine, 2021,Volume: 7,Issue: 2,Page: 209-216
Authors:  Xu, Xiao Huang;  Chen, Yu Chi;  Xu, Yu Lian;  Feng, Zhe Ling;  Liu, Qian Yu;  Guo, Xia;  Lin, Li Gen;  Lu, Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/12/07
Anticancer  Autophagy  Garcinone e  Lysosome  Tfeb  
Quercetin induces p53-independent cancer cell death through lysosome activation by the transcription factor EB and Reactive Oxygen Species-dependent ferroptosis Journal article
British Journal of Pharmacology, 2021,Volume: 178,Issue: 5,Page: 1133-1148
Authors:  Wang,Zi Xuan;  Ma,Jing;  Li,Xin Yu;  Wu,Yong;  Shi,Huan;  Chen,Yao;  Lu,Guang;  Shen,Han Ming;  Lu,Guo Dong;  Zhou,Jing
Favorite |  | TC[WOS]:37 TC[Scopus]:36 | Submit date:2021/03/02
Ferroptosis  Lysosome  Quercetin  Ros  Transcription Factor Eb  
Synthesis and biological effect of lysosome-targeting fluorescent anion transporters with enhanced anionophoric activity Journal article
Bioorganic and Medicinal Chemistry Letters, 2020,Volume: 30,Issue: 19
Authors:  Hong,Xiao Qiao;  He,Xiang Yu;  Tam,Kin Yip;  Chen,Wen Hua
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/04
Cathepsin b Enzyme  Fluorescent Anion Transporter  Lysosomal Alkalization  Lysosome Targeting  
Cholesterol trafficking: An emerging therapeutic target for angiogenesis and cancer Journal article
Cells, 2019,Volume: 8,Issue: 5
Authors:  Lyu, Junfang;  Yang, Eun Ju;  Shim, Joong Sup
Favorite |  | TC[WOS]:23 TC[Scopus]:25 | Submit date:2022/05/17
Angiogenesis  Cholesterol traffcking  Lysosome  mTOR  NPC1  
Exploration the effect of structural adjustment on identifying medium and bio-targeting based on two similar coumarin compounds Journal article
Sensors and Actuators, B: Chemical, 2018,Volume: 272,Page: 574-581
Authors:  Yao,Shun;  Zhang,Gaojian;  Wang,Haiyan;  Song,Jinjin;  Liu,Tianyan;  Yang,Mingdi;  Yu,Jianhua;  Yang,Xingyuan;  Tian,Yupeng;  Zhang,Xuanjun;  Zhou,Hongping
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/03/04
Bio-imaging application  Copper ion  Fluorescence probes  Lysosome  Mercuric ion  Mitochondria  
Exploration the effect of structural adjustment on identifying medium and bio-targeting based on two similar coumarin compounds Journal article
SENSORS AND ACTUATORS B-CHEMICAL, 2018,Volume: 272,Page: 574-581
Authors:  Yao, Shun;  Zhang, Gaojian;  Wang, Haiyan;  Song, Jinjin;  Liu, Tianyan;  Yang, Mingdi;  Yu, Jianhua;  Yang, Xingyuan;  Tian, Yupeng;  Zhang, Xuanjun;  Zhou, Hongping
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2018/10/30
Fluorescence Probes  Mercuric Ion  Copper Ion  Lysosome  Mitochondria  Bio-imaging Application