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Lysosomal TPCN (two pore segment channel) inhibition ameliorates beta-amyloid pathology and mitigates memory impairment in Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 3,Page: 624-642
Authors:  Tong, Benjamin Chun Kit;  Wu, Aston Jiaxi;  Huang, Alexis Shiying;  Dong, Rui;  Malampati, Sandeep;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Zhu, Zhou;  Su, Chengfu;  Liu, Jia;  Song, Juxian;  Lu, Jia Hong;  Tan, Jieqiong;  Pan, Weidong;  Li, Min;  Cheung, King Ho
Favorite |  | TC[WOS]:5 TC[Scopus]:7 | Submit date:2022/05/17
Alzheimer Disease  Autophagy-lysosomal Pathway  Calcium Ion  Presenilin-1  Two Pore Segment Channel 2  
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition Journal article
Phytomedicine, 2022,Volume: 96
Authors:  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Senapati, Sanjib;  Malampati, Sandeep;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Guan, Xin Jie;  Tong, Benjamin Chun Kit;  Cheung, King Ho;  Tan, Jie Qiong;  Lu, Jia Hong;  Durairajan, Siva Sundara Kumar;  Song, Ju Xian;  Li, Min
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2022/03/04
3xtg-ad Mice  Alzheimer's Disease  Hdac6  P301s-tau Mice  Phospho-tau  Protopine  
A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro Journal article
International Journal of Molecular Sciences, 2020,Volume: 21,Issue: 4
Authors:  Wang,Ziying;  Yang,Chuanbin;  Liu,Jia;  Tong,Benjamin Chun Kit;  Zhu,Zhou;  Malampati,Sandeep;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Cheung,King Ho;  Iyaswamy,Ashok;  Su,Chengfu;  Lu,Jiahong;  Song,Juxian;  Li,Min
Favorite |  | TC[WOS]:19 TC[Scopus]:18 | Submit date:2021/03/02
Curcumin Derivatives  Mtorc1  Parkinson’s Disease  Tfeb  Α-synuclein  
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models Journal article
Aging Cell, 2020,Volume: 19,Issue: 2
Authors:  Song,Ju Xian;  Malampati,Sandeep;  Zeng,Yu;  Durairajan,Siva Sundara Kumar;  Yang,Chuan Bin;  Tong,Benjamin Chun Kit;  Iyaswamy,Ashok;  Shang,Wen Bin;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Zhu,Zhou;  Cheung,King Ho;  Lu,Jia Hong;  Tang,Chunzhi;  Xu,Nenggui;  Li,Min
Favorite |  | TC[WOS]:47 TC[Scopus]:49 | Submit date:2021/03/02
Alzheimer's Disease  Beta-amyloid  Curcumin Analog C1  Mapt/tau  Tfeb  
Targeting Aggrephagy for the Treatment of Alzheimer's Disease Journal article
Cells, 2020,Volume: 9,Issue: 2
Authors:  Malampati, Sandeep;  Song, Ju Xian;  Chun-Kit Tong, Benjamin;  Nalluri, Anusha;  Yang, Chuan Bin;  Wang, Ziying;  Gopalkrishnashetty Sreenivasmurthy, Sravan;  Zhu, Zhou;  Liu, Jia;  Su, Chengfu;  Krishnamoorthi, Senthilkumar;  Iyaswamy, Ashok;  Cheung, King Ho;  Lu, Jia Hong;  Li, And Min
Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2021/12/03
Aggregates  Aggrephagy  Alzheimer’s Disease  Selective Autophagy