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Enhanced Protein Damage Clearance Induces Broad Drug Resistance in Multitype of Cancers Revealed by an Evolution Drug-Resistant Model and Genome-Wide siRNA Screening Journal article
Advanced Science, 2020,Volume: 7,Issue: 23
Authors:  Shao,Fangyuan;  Lyu,Xueying;  Miao,Kai;  Xie,Lisi;  Wang,Haitao;  Xiao,Hao;  Li,Jie;  Chen,Qiang;  Ding,Renbo;  Chen,Ping;  Xing,Fuqiang;  Zhang,Xu;  Luo,Guang Hui;  Zhu,Wenli;  Cheng,Gregory;  Lon,Ng Wai;  Martin,Scott E.;  Wang,Guanyu;  Chen,Guokai;  Dai,Yunlu;  Deng,Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:2 | Submit date：2021/03/02
Broad Drug Resistance  Caspase 3 Activation  Patient-derived Organoid  Proteolysis  Rnai Screening  
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:9 TC[Scopus]:10 | Submit date：2020/09/16
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date：2021/03/02
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis Journal article
Advanced Science, 2020,Volume: 7,Issue: 6
Authors:  Chen,Qiang;  Lei,Josh Haipeng;  Bao,Jiaolin;  Wang,Haitao;  Hao,Wenhui;  Li,Licen;  Peng,Cheng;  Masuda,Takaaki;  Miao,Kai;  Xu,Jun;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:17 TC[Scopus]:18 | Submit date：2020/09/16
Atm-ampk-drp1  Brca1  Inflammasomes  Mitochondrial Dynamics  Mitophagy  
Imaging of macrophage mitochondria dynamics in vivo reveals cellular activation phenotype for diagnosis Journal article
Theranostics, 2020,Volume: 10,Issue: 7,Page: 2897-2917
Authors:  Li,Yue;  He,Yuan;  Miao,Kai;  Zheng,Ying;  Deng,Chuxia;  Liu,Tzu Ming
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date：2020/09/16
In Vivo imagIng  Liposome  Macrophage  Mitochondria  Multiphoton Microscopy  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2020/09/16
Defined Factors  Human Embryonic Stem Cells  Keratinocyte Differentiation  
Non-classical estrogen signaling in ovarian cancer improves chemo-sensitivity and patients outcome Journal article
THERANOSTICS, 2019,Volume: 9,Issue: 13,Page: 3952-3965
Authors:  Dapeng Hao;  Jingjing Li;  Jianlin Wang;  Yuan Meng;  Zhiqiang Zhao;  Chao Zhang;  Kai Miao;  Chuxia Deng;  Benjamin K. Tsang;  Li Wang;  Li-jun Di
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Ovarian Cancer  Estrogen Signaling  Deficiency Of Homologous-recombination  Chemotherapy  Hormone Replacement  
CuS Nanoparticles as a Photodynamic Nanoswitch for Abrogating Bypass Signaling To Overcome Gefitinib Resistance Journal article
NANO LETTERS, 2019,Volume: 19,Issue: 5,Page: 3344-3352
Authors:  Xiajing Gu;  Yuanyuan Qiu;  Miao Lin;  Kai Cui;  Gaoxian Chen;  Yingzhi Chen;  Chenchen Fan;  Yongming Zhang;  Lu Xu;  Hongzhuan Chen;  Jian-Bo Wan;  Wei Lu;  Zeyu Xiao
Favorite |  | TC[WOS]:13 TC[Scopus]:12 | Submit date：2020/04/22
Gefitinib  Cus Nanoparticles  Non-small Cell Lung Cancer  Rug Resistance  Active Oxygen Species  
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice Journal article
Journal of Biological Chemistry, 2019,Volume: 294,Issue: 4,Page: 1142-1151
Authors:  Miao,Kai;  Zhang,Xin;  Su,Sek Man;  Zeng,Jianming;  Huang,Zebin;  Chan,Un In;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:6 TC[Scopus]:8 | Submit date：2020/09/16
Targeting immune checkpoint B7-H3 antibody-chlorin e6 bioconjugates for spectroscopic photoacoustic imaging and photodynamic therapy Journal article
Chemical Communications, 2019,Volume: 55,Issue: 95,Page: 14255-14258
Authors:  Zhu,Lipeng;  Liu,Jie;  Zhou,Guangyu;  Ng,Hoi Man;  Ang,Irene L.;  Ma,Guofang;  Liu,Yubin;  Yang,Shuo;  Zhang,Fengjuan;  Miao,Kai;  Poon,Terence C.W.;  Zhang,Xuanjun;  Yuan,Zhen;  Deng,Chu Xia;  Zhao,Qi
Favorite |  | TC[WOS]:16 TC[Scopus]:16 | Submit date：2020/09/16