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Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 9,Page: 3567-3593
Authors:  Wang, Xuan;  Hua, Peng;  He, Chengwei;  Chen, Meiwan
Favorite |  | TC[WOS]:3 TC[Scopus]:5 | Submit date:2022/05/17
Anticancer  Autophagy  Combination Therapies  Ferroptosis  Nanomedicine  Necroptosis  Non-apoptotic Cell Death  Pyroptosis  
3-O-acetylrubianol C (3AR-C) induces RIPK1-dependent programmed cell death by selective inhibition of IKKβ Journal article
FASEB Journal, 2020,Volume: 34,Issue: 3,Page: 4369-4383
Authors:  Kang,Kidong;  Quan,Khong Trong;  Byun,Hee Sun;  Lee,So Ra;  Piao,Xuezhe;  Ju,Eunjin;  Park,Kyeong Ah;  Sohn,Kyung Cheol;  Shen,Han Ming;  Na,Min Kyun;  Hur,Gang Min
Favorite |  | TC[WOS]:3 TC[Scopus]:2 | Submit date:2021/03/02
3ar-c  Apoptosis  Ikkβ  Necroptosis  Phosphorylation  Ripk1  Tnf  
An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by MAM Conference paper
Collection of 18th World Congress of Basic and Clinical Pharmacology (WCP2018)
Authors:  Yu, J.;  Wu, X.X.;  Wang, C.X.;  Sun, W.;  Hou, Y.;  Zhang, Y.Y.;  Li, Z.W.;  Lu, J.;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/26
MAM  necroptosis  glioma  
NQO1 dependent non-canonical necroptosis mediated by ROS and RIP1/RIP3 in parallel in glioma cancer cells Conference paper
Collection of The 2018 International Conference on the Pharmacology of Traditional Medicine of the Belt and Road Initiative
Authors:  Yu, J.;  Wu, X.X.;  Wang, C.X.;  Gao, H.W.;  Sun, W.;  Lu, J.;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/26
MAM  glioblastomas  non-canonical necroptosis  NQO1  
Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice Journal article
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2018,Volume: 344,Page: 35-45
Authors:  Guo, Yanling;  Wu, Xiaxia;  Wu, Qin;  Lu, Yuanfu;  Shi, Jingshan;  Chen, Xiuping
Favorite |  | TC[WOS]:34 TC[Scopus]:35 | Submit date:2018/10/30
15,16-dihydrotanshinone i  Ulcerative Colitis  Inflammation  Necroptosis  
An NQO1 dependent ROS and RIP1/RIP3 mediated necroptosis induced in glioma cancer cells by a natural product, 2-Methoxy-6-acetyl-7-methyljuglone (MAM) Conference paper
Collection The 6th Guangzhou International Symposium on Oncology
Authors:  Yu, J.;  Li, Z.W.;  Hou, Y.;  Yuan, R.Y.K.;  Lu, J.;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/26
MAM  necroptosis  NQO1  ROS  RIP1/RIP3  
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. Journal article
Free Radical Biology & Medicine, 2017,Page: 433-444
Authors:  Sun, W;  Wu, XX;  Gao, HW;  Yu, J;  Zhao, WW;  Lu, J.;  Wang, JH;  Du, GH;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/31
necroptosis  c-Jun N-terminal kinase  calcium  
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells Journal article
FREE RADICAL BIOLOGY AND MEDICINE, 2017,Volume: 108,Page: 433-444
Authors:  Sun, Wen;  Wu, Xiaxia;  Gao, Hongwei;  Yu, Jie;  Zhao, Wenwen;  Lu, Jin-Jian;  Wang, Jinhua;  Du, Guanhua;  Chen, Xiuping
Favorite |  | TC[WOS]:85 TC[Scopus]:88 | Submit date:2018/10/30
Necroptosis  Cell Death  Ros  Calcium  
Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion Journal article
REDOX BIOLOGY, 2017,Volume: 11,Page: 524-534
Authors:  Zhao, Wenwen;  Feng, Haitao;  Sun, Wen;  Liu, Kang;  Lu, Jin-Jian;  Chen, Xiuping
Favorite |  | TC[WOS]:61 TC[Scopus]:63 | Submit date:2018/10/30
Apoptosis  Necroptosis  Reactive Oxygen Species  Nox4  Mitochondria  Endothelial Cells  
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells. Journal article
Free Radical Biology & Medicine, 2016,Page: 61-77
Authors:  Sun, W ;  Bao, JL;  Lin, W;  Gao, HW;  Zhao, WW;  Zhang, Q. W.;  Leung, C. H.;  Ma, DL;  Lu, J.;  Chen, X. P.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/03/31
Apoptosis  Cancer  MAM  NO  Necroptosis  ROS