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Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells Journal article
Stem Cell Research and Therapy, 2022,Volume: 13,Issue: 1
Authors:  Deng, Chunhao;  Zhang, Zhaoying;  Xu, Faxiang;  Xu, Jiaqi;  Ren, Zhili;  Godoy-Parejo, Carlos;  Xiao, Xia;  Liu, Weiwei;  Zhou, Zhou;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
Cell culture  hPSCs  Pluripotency  Thyroid Hormone  Triiodothyronine (T3)  Trophoblast  
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 12
Authors:  Meng, Ya;  Song, Chengcheng;  Ren, Zhili;  Li, Xiaohong;  Yang, Xiangyu;  Ai, Nana;  Yang, Yang;  Wang, Dongjin;  Zhan, Meixiao;  Wang, Jiaxian;  Lei, Chon Lok;  Liu, Weiwei;  Ge, Wei;  Lu, Ligong;  Chen, Guokai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/08
Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells Journal article
Stem Cell Research and Therapy, 2021,Volume: 12,Issue: 1
Authors:  Zhang, Yumeng;  Xu, Jiaqi;  Ren, Zhili;  Meng, Ya;  Liu, Weiwei;  Lu, Ligong;  Zhou, Zhou;  Chen, Guokai
Favorite |  | TC[WOS]:5 TC[Scopus]:4 | Submit date:2021/12/09
Casein Kinase 1 (Ck1)  Human Embryonic Stem Cells  Kinase Inhibitor  Nicotinamide  Pancreatic Progenitors  Rho-associated Protein Kinase (Rock)  
Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells Journal article
Cell Reports, 2021,Volume: 37,Issue: 9
Authors:  Xu, Faxiang;  Deng, Chunhao;  Ren, Zhili;  Sun, Liangyu;  Meng, Ya;  Liu, Weiwei;  Wan, Jianbo;  Chen, Guokai
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
cellular state  hPSC  lipid  LPA  metabolism  mitochondria  pluripotency  transcriptome  
Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:  Ren,Zhili;  Zhong,Hui;  Song,Chengcheng;  Deng,Chunhao;  Hsieh,Hsun Ting;  Liu,Weiwei;  Chen,Guokai
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date:2021/03/02
Akt  Caspase  Cell Survival  Gsk3  Human Embryonic Stem Cells  Insulin  Mitochondrial Respiration  
Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways Journal article
Stem Cell Research and Therapy, 2020,Volume: 11,Issue: 1
Authors:  Ma,Rui;  Ren,Zhili;  Li,Bin;  Siu,Shirley W.I.;  Chen,Guokai;  Kwok,Hang Fai
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/04
Embryonic Stem Cell  Peptide Modification  Pluripotency  Self-renewal  Venom Peptide  
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:  Zhong,Hui;  Ren,Zhili;  Wang,Xiaoyan;  Miao,Kai;  Ni,Wenjun;  Meng,Ya;  Lu,Ligong;  Wang,Chunming;  Liu,Weiwei;  Deng,Chu Xia;  Xu,Ren He;  Chen,Guokai
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2020/09/16
Defined Factors  Human Embryonic Stem Cells  Keratinocyte Differentiation  
Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells Journal article
Cell Reports, 2019,Volume: 29,Issue: 11,Page: 3374-3384.e5
Authors:  Yang,Yang;  Ren,Zhili;  Xu,Faxiang;  Meng,Ya;  Zhang,Yumeng;  Ai,Nana;  Long,Yan;  Fok,Hio Ian;  Deng,Chunhao;  Zhao,Xianyang;  Huang,Liancheng;  Zhao,Qi;  Wang,Jiaxian;  Liu,Weiwei;  Ge,Wei;  Chen,Guokai
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2021/03/02
Cardiomyocyte  Casein Kinase Ii  Heterogeneity  Human Embryonic Stem Cells  Igf  Insulin  Mesoderm  Pi3k  Temporal Regulation  Wnt  
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:  Chengcheng Song;  Faxiang Xu;  Zhili Ren;  Yumeng Zhang;  Ya Meng;  Yiqi Yang;  Shreyas Lingadahalli;  Edwin Cheung;  Gang Li;  Weiwei Liu;  Jianbo Wan;  Yang Zhao;  Guokai Chen
Favorite |  | TC[WOS]:14 TC[Scopus]:20 | Submit date:2020/04/22
Hescs  Pyruvate  Bmp4  Glycolysis  Tca Cycle  Ampk  Wnt  Metabolism  Mesoderm  Differentiation  
The Suppression of Medium Acidosis Improves the Maintenance and Differentiation of Human Pluripotent Stem Cells at High Density in Defined Cell Culture Medium Journal article
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018,Volume: 14,Issue: 5,Page: 485-496
Authors:  Liu, Weiwei;  Ren, Zhili;  Lu, Kai;  Song, Chengcheng;  Cheung, Edwin Chong Wing;  Zhou, Zhou;  Chen, Guokai
Favorite |  | TC[WOS]:14 TC[Scopus]:15 | Submit date:2018/10/30
Human Pluripotent Stem Cells  Acidosis  Glycolysis  Cell Death  Differentiation