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O-GlcNAcylation promotes fatty acid synthase activity under nutritional stress as a pro-survival mechanism in cancer cells Journal article
Proteomics, 2022,Volume: 22,Issue: 9
Authors:  Wong, Yin Kwan;  Wang, Jigang;  Lim, Teck Kwang;  Lin, Qingsong;  Yap, Celestial T.;  Shen, Han Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/13
fatty acid synthase  iTRAQ  liquid chromatography – tandem mass spectrometry  metabolic labelling  O-GlcNAc  
NAMPT mitigates colitis severity by supporting redox-sensitive activation of phagocytosis in inflammatory macrophages Journal article
Redox Biology, 2022,Volume: 50
Authors:  Hong, Sun Mi;  Lee, A. Yeon;  Hwang, Sung Min;  Ha, Yu Jin;  Kim, Moo Jin;  Min, Seongki;  Hwang, Won;  Yoon, Gyesoon;  Kwon, So Mee;  Woo, Hyun Goo;  Kim, Hee Hoon;  Jeong, Won Il;  Shen, Han Ming;  Im, Sin Hyeog;  Lee, Dakeun;  Kim, You Sun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/04
Colitis  Inflammatory Bowel Disease  Macrophage  Nad++  Nampt  Phagocytic Activity  
Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1019-1040
Authors:  Zhang, Wei;  Xu, Chengchao;  Sun, Jichao;  Shen, Han Ming;  Wang, Jigang;  Yang, Chuanbin
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date：2022/04/06
Alzheimer's Disease (Ad)  Amyloid Beta (Aβ) Peptides  Autophagy  Autophagy Enhancers  Autophagy–lysosomal Pathway  Mapt/tau  Mitophagy  Neurodegenerative Diseases  
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow Journal article
Nature Biomedical Engineering, 2022,Volume: 6,Issue: 1,Page: 76-93
Authors:  Xie, Chenglong;  Zhuang, Xu Xu;  Niu, Zhangming;  Ai, Ruixue;  Lautrup, Sofie;  Zheng, Shuangjia;  Jiang, Yinghui;  Han, Ruiyu;  Gupta, Tanima Sen;  Cao, Shuqin;  Lagartos-Donate, Maria Jose;  Cai, Cui Zan;  Xie, Li Ming;  Caponio, Domenica;  Wang, Wen Wen;  Schmauck-Medina, Tomas;  Zhang, Jianying;  Wang, He ling;  Lou, Guofeng;  Xiao, Xianglu;  Zheng, Wenhua;  Palikaras, Konstantinos;  Yang, Guang;  Caldwell, Kim A.;  Caldwell, Guy A.;  Shen, Han Ming;  Nilsen, Hilde;  Lu, Jia Hong;  Fang, Evandro F.
Favorite |  | TC[WOS]:2 TC[Scopus]:6 | Submit date：2022/02/21
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1 Journal article
Acta Pharmaceutica Sinica B, 2022
Authors:  Luo, Piao;  Liu, Dandan;  Zhang, Qian;  Yang, Fan;  Wong, Yin Kwan;  Xia, Fei;  Zhang, Junzhe;  Chen, Jiayun;  Tian, Ya;  Yang, Chuanbin;  Dai, Lingyun;  Shen, Han Ming;  Wang, Jigang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/17
ABPP  Anti-oxidant  Celastrol  Ferroptosis  Hepatic fibrosis  HO-1  Peroxiredoxin  Reactive oxygen species  
Cholesterol-enriched membrane micro-domaindeficiency induces doxorubicin resistancevia promoting autophagy in breast cancer Journal article
Molecular Therapy - Oncolytics, 2021,Volume: 23,Page: 311-329
Authors:  Shi, Yin;  Ye, Zu;  Lu, Guang;  Yang, Naidi;  Zhang, Jianbin;  Wang, Liming;  Cui, Jianzhou;  del Pozo, Miguel A.;  Wu, Yihua;  Xia, Dajing;  Shen, Han Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/12/08
Autophagy  Breast Cancer  Cav1  Cholesterol-enriched Membrane Micro-domains  Doxorubicin Resistance  Vamp3  
DUSP16 promotes cancer chemoresistance through regulation of mitochondria-mediated cell death Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Low, Heng Boon;  Wong, Zhen Lim;  Wu, Bangyuan;  Kong, Li Ren;  Png, Chin Wen;  Cho, Yik Lam;  Li, Chun Wei;  Xiao, Fengchun;  Xin, Xuan;  Yang, Henry;  Loo, Jia Min;  Lee, Fiona Yi Xin;  Tan, Iain Bee Huat;  DasGupta, Ramanuj;  Shen, Han Ming;  Schwarz, Herbert;  Gascoigne, Nicholas R.J.;  Goh, Boon Cher;  Xu, Xiaohong;  Zhang, Yongliang
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date：2021/11/30
Mito-Bomb: Targeting Mitochondria for Cancer Therapy Journal article
Advanced Materials, 2021,Volume: 33,Issue: 43
Authors:  Guo, Xiaolu;  Yang, Naidi;  Ji, Wenhui;  Zhang, Hang;  Dong, Xiao;  Zhou, Zhiqiang;  Li, Lin;  Shen, Han Ming;  Yao, Shao Q.;  Huang, Wei
Favorite |  | TC[WOS]:11 TC[Scopus]:15 | Submit date：2021/11/30
Cancer Therapy  Chemodynamic Therapy  Mitochondria  Photodynamic Therapy  Photothermal Therapy  
Full-coverage regulations of autophagy by ROS: from induction to maturation Journal article
Autophagy, 2021
Authors:  Zhou, Jing;  Li, Xin Yu;  Liu, Yu Jia;  Feng, Ji;  Wu, Yong;  Shen, Han Ming;  Lu, Guo Dong
Favorite |  | TC[WOS]:4 TC[Scopus]:6 | Submit date：2021/11/30
Atgs  Autophagy  Oxidative Regulation  Protein Thiols  Ros  
Targeting cd82/kai1 for precision therapeutics in surmounting metastatic potential in breast cancer Journal article
Cancers, 2021,Volume: 13,Issue: 17
Authors:  Viera, Maximillian;  Yip, George Wai Cheong;  Shen, Han Ming;  Baeg, Gyeong Hun;  Bay, Boon Huat
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/11/30
Cd82 Mimics  Epigenetic Drugs  Etoposide  Metastasis Suppressor  Tetraspanins  Tyrosine Kinase Inhibitors