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| Simultaneous targeting of NPC1 and VDAC1 by itraconazole leads to synergistic inhibition of MTOR signaling and angiogenesis Journal article
ACS Chemical Biology, 2017,Volume: 12,Issue: 1,Page: 174
Authors: Head S.A.; Shi W.Q.; Yang E.J.; Nacev B.A.; Hong S.Y.; Pasunooti K.K.; Li R.-J.; Shim J.S.; Liu J.O.
  Favorite | | TC[WOS]:49 TC[Scopus]:48 | Submit date：2018/10/30 |
| Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway Journal article
Scientific Reports, 2016,Volume: 6
Authors: Cho Y.S.; Yen C.-N.; Shim J.S. ; Kang D.H.; Kang S.W.; Liu J.O.; Kwon H.J.
Favorite | | TC[WOS]:23 TC[Scopus]:24 | Submit date：2019/01/15 |
| Revisiting Non-Cancer Drugs for Cancer Therapy Journal article
Current Topics in Medicinal Chemistry, 2016,Volume: 16,Issue: 19,Page: 2144-2155
Authors: Yang E.J.; Wu C.; Liu Y.; Lv J.; Shim J.S.
Favorite | | TC[WOS]:12 TC[Scopus]:0 | Submit date：2019/01/15
Cancer Disulfiram Doxycycline Drug Repositioning Existing Drugs Mebendazole Pyrvinium Pamoate Triclosan |
| Divergence of antiangiogenic activity and hepatotoxicity of different stereoisomers of itraconazole Journal article
Clinical Cancer Research, 2016,Volume: 22,Issue: 11,Page: 2709-2720
Authors: Shim J.S.; Li R.-J.; Bumpus N.N.; Head S.A.; Pasunooti K.K.; Yang E.J.; Lv J.; Shi W.; Liu J.O.
Favorite | | TC[WOS]:11 TC[Scopus]:11 | Submit date：2019/01/15 |
| The small molecule R-(-)-β-O-methylsynephrine binds to nucleoporin 153 kDa and inhibits angiogenesis Journal article
International Journal of Biological Sciences, 2015,Volume: 11,Issue: 9,Page: 1088-1099
Authors: Kim N.H.; Pham N.B.; Quinn R.J.; Shim J.S.; Cho H.; Cho S.M.; Park S.W.; Kim J.H.; Seok S.H.; Oh J.-W.; Kwon H.J.
Favorite | | TC[WOS]:8 TC[Scopus]:11 | Submit date：2019/01/15
Angiogenesis Natural Product Nup153 Small Molecule Target Identification |
| First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass Journal article
eLife, 2015,Volume: 4,Issue: 2015-07-01
Authors: Wang G.; Rajpurohit S.K.; Delaspre F.; Walker S.L.; White D.T.; Ceasrine A.; Kuruvilla R.; Li R.-J.; Shim J.S.; Liu J.O.; Parsons M.J.; Mumm J.S.
Favorite | | TC[WOS]:43 TC[Scopus]:66 | Submit date：2018/10/30 |
| Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells Journal article
Proceedings of the National Academy of Sciences of the United States of America, 2015,Volume: 112,Issue: 52,Page: E7276
Authors: Head S.A.; Shi W.; Zhao L.; Gorshkov K.; Pasunooti K.; Chen Y.; Deng Z.; Li R.-J.; Shim J.S.; Tan W.; Hartung T.; Zhang J.; Zhao Y.; Colombini M.; Liu J.O.
Favorite | | TC[WOS]:62 TC[Scopus]:65 | Submit date：2018/10/30
Angiogenesis Itraconazole Metabolism Mitochondria VDAC1 |
| Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism Journal article
Cancer Letters, 2015,Volume: 362,Issue: 1,Page: 106-115
Authors: Shim J.S.; Li R.-J.; Lv J.; Head S.A.; Yang E.J.; Liu J.O.
Favorite | | TC[WOS]:17 TC[Scopus]:19 | Submit date：2019/01/15
Angiogenesis Cholesterol Trafficking Selective Estrogen Receptor Modulator Tamoxifen |
| Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer Journal article
British Journal of Pharmacology, 2014,Volume: 171,Issue: 19,Page: 4478-4489
Authors: Wang M.; Shim J.S.; Li R.-J.; Dang Y.; He Q.; Das M.; Liu J.O.
Favorite | | TC[WOS]:19 TC[Scopus]:21 | Submit date：2019/01/15 |
| Purpurin inhibits adipocyte-derived leucine aminopeptidase and angiogenesis in a zebrafish model Journal article
Biochemical and Biophysical Research Communications, 2014,Volume: 450,Issue: 1,Page: 561-567
Authors: Park H.; Shim J.S.; Kim B.S.; Jung H.J.; Huh T.-L.; Kwon H.J.
Favorite | | TC[WOS]:16 TC[Scopus]:19 | Submit date：2019/01/15
Adipocyte-derived Leucine Aminopeptidase (A-lap) Angiogenesis Drug Screening Purpurin |
