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Applications of Molecular Dynamics Simulation in Protein Study Journal article
Membranes, 2022,Volume: 12,Issue: 9
Authors:  Sinha, Siddharth;  Tam, Benjamin;  Wang, San Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/10/06
Ace-2 Membrane Receptor  Enhanced Sampling Techniques  Gpcrs  Lipid-protein Interactions  Membrane Dynamics  Molecular Dynamics Simulations  
Identification of deleterious variants of uncertain significance in BRCA2 BRC4 repeat through molecular dynamics simulations Journal article
Briefings in functional genomics, 2022,Volume: 21,Issue: 3,Page: 202-215
Authors:  Sinha, Siddharth;  Qin, Zixin;  Tam, Benjamin;  Wang, San Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/06/10
Brca2 Brc4  Auc  Deleterious  Molecular Dynamics Simulations  Pca  Roc  Tolerated  Vus Classification  
Rbd double mutations of sars-cov-2 strains increase transmissibility through enhanced interaction between rbd and ace2 receptor Journal article
Viruses, 2022,Volume: 14,Issue: 1
Authors:  Sinha, Siddharth;  Tam, Benjamin;  Wang, San Ming
Favorite |  | TC[WOS]:5 TC[Scopus]:4 | Submit date:2022/02/21
Antibody Escape  Free Energy  Md Simulations  Mm/gbsa  Sars-cov-2  Variants  
Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability Journal article
International Journal of Molecular Sciences, 2021,Volume: 22,Issue: 21
Authors:  Tam, Benjamin;  Sinha, Siddharth;  Qin, Zixin;  Wang, San Ming
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Deleterious  Molecular Dynamic Simulations  Ramachandran Plot  Tp53  Vus  
BRCA1 and BRCA2 Variation in Taiwanese General Population and the Cancer Cohort Journal article
Frontiers in Molecular Biosciences, 2021,Volume: 8
Authors:  Chian, Jiasheng;  Sinha, Siddharth;  Qin, Zixin;  Wang, San Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:2 | Submit date:2021/12/08
Brca1  Brca2  Ethnicity  Pathogenic  Population  Prevalence  
Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition Journal article
BMC Genomics, 2020,Volume: 21,Issue: 1
Authors:  Gupta,Hemant;  Chandratre,Khyati;  Sinha,Siddharth;  Huang,Teng;  Wu,Xiaobing;  Cui,Jian;  Zhang,Michael Q.;  Wang,San Ming
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/03/02
1000 Genomes  Core Promoter  Eqtl  Exome  Gwas  Variation  
Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model Journal article
Computational and Structural Biotechnology Journal, 2020,Volume: 18,Page: 4033-4039
Authors:  Tam,Benjamin;  Sinha,Siddharth;  Wang,San Ming
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/03/02
Molecular Dynamic Simulation  Pathogenic  Protein Structure  Ramachandran Plot  Tp53  Variant Of Uncertain Significance  
Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation Journal article
Computational and Structural Biotechnology Journal, 2020,Volume: 18,Page: 723-736
Authors:  Sinha,Siddharth;  Wang,San Ming
Favorite |  | TC[WOS]:29 TC[Scopus]:33 | Submit date:2021/03/02
BRCA1  BRCT  Molecular dynamics simulation  PCA  Unclassified variants  VUS  
Coupled genome-wide DNA methylation and transcription analysis identified rich biomarkers and drug targets in triple-negative breast cancer Journal article
Cancers, 2019,Volume: 11,Issue: 11
Authors:  Guo,Maoni;  Sinha,Siddharth;  Wang,San Ming
Favorite |  | TC[WOS]:7 TC[Scopus]:5 | Submit date:2021/03/02
Dna Methylation  Gene Expression  Therapeutic Targets  Tnbc  
Germline variation in BRCA1/2 is highly ethnic-specific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients Journal article
International Journal of Cancer, 2019,Volume: 145,Issue: 4,Page: 962-973
Authors:  Bhaskaran,Shanmuga Priya;  Chandratre,Khyati;  Gupta,Hemant;  Zhang,Li;  Wang,Xiaoyu;  Cui,Jian;  Kim,Yeong C.;  Sinha,Siddharth;  Jiang,Luhan;  Lu,Boya;  Wu,Xiaobing;  Qin,Zixin;  Huang,Teng;  Wang,San Ming
Favorite |  | TC[WOS]:32 TC[Scopus]:41 | Submit date:2021/03/02
BRCA1  BRCA2  breast cancer  Chinese  ethnic-specific  mutation  population