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A novel bioengineered fragment peptide of Vasostatin-1 exerts smooth muscle pharmacological activities and anti-angiogenic effects via blocking VEGFR signalling pathway Journal article
Computational and Structural Biotechnology Journal, 2021,Volume: 19,Page: 2664-2675
Authors:  Wei, Ran;  Wu, Qiushuang;  Ai, Nana;  Wang, Lei;  Zhou, Mei;  Shaw, Chris;  Chen, Tianbao;  Ye, Richard Dequan;  Ge, Wei;  Siu, Shirley W.I.;  Kwok, Hang Fai
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/09/17
Anti-angiogenesis  Chromogranin a  Vasostatin-1  Vegfr2  
Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways Journal article
Stem Cell Research and Therapy, 2020,Volume: 11,Issue: 1
Authors:  Ma,Rui;  Ren,Zhili;  Li,Bin;  Siu,Shirley W.I.;  Chen,Guokai;  Kwok,Hang Fai
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/04
Embryonic stem cell  Peptide modification  Pluripotency  Self-renewal  Venom peptide  
Deep-AmPEP30: Improve Short Antimicrobial Peptides Prediction with Deep Learning Journal article
Molecular Therapy - Nucleic Acids, 2020,Volume: 20,Page: 882-894
Authors:  Yan,Jielu;  Bhadra,Pratiti;  Li,Ang;  Sethiya,Pooja;  Qin,Longguang;  Tai,Hio Kuan;  Wong,Koon Ho;  Siu,Shirley W.I.
Favorite |  | TC[WOS]:20 TC[Scopus]:22 | Submit date:2021/03/04
AmPEP  ampicillin  antimicrobial peptide  AxPEP  Candida glabrata  convolutional neural network  drug discovery  machine learning  reduced amino acid composition  
In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide Journal article
Molecular Therapy - Oncolytics, 2020,Volume: 16,Page: 7-19
Authors:  Ma,Rui;  Wong,Sin Wa;  Ge,Lilin;  Shaw,Chris;  Siu,Shirley W.I.;  Kwok,Hang Fai
Favorite |  | TC[WOS]:14 TC[Scopus]:13 | Submit date:2021/03/04
angiogenesis  anticancer peptides  antimicrobial peptides  apoptosis  drug discovery and development  molecular dynamics  targeted therapy