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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models Journal article
Redox Biology, 2022,Volume: 51
Authors:  Iyaswamy, Ashok;  Wang, Xueli;  Krishnamoorthi, Senthilkumar;  Kaliamoorthy, Venkatapathy;  Sreenivasmurthy, Sravan G.;  Kumar Durairajan, Siva Sundara;  Song, Ju Xian;  Tong, Benjamin Chun kit;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Cheung, King Ho;  Lu, Jia Hong;  Tan, Jie Qiong;  Li, Hung Wing;  Wong, Man Shing;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
3xtg-ad  5xfad  Alzheimer's Disease  Aβ-aggregate Inhibition  Aβ-targeting  Theranostic  
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2 Journal article
Acta Pharmacologica Sinica, 2022,Volume: 43,Issue: 5,Page: 1251-1263
Authors:  Yang, Chuan bin;  Liu, Jia;  Tong, Benjamin Chun Kit;  Wang, Zi ying;  Zhu, Zhou;  Su, Cheng fu;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Wu, Jia xi;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Huang, Shi ying;  Cheung, King ho;  Song, Ju xian;  Tan, Jie qiong;  Lu, Jia hong;  Li, Min
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2022/05/13
15-deoxy-∆-12,14-prostaglandin J2 (15d-pgJ2)  Apoptosis  Atf4  Autophagy And Lysosome Biogenesis  Er Stress  Transcriptional Factor Eb (tfEb)  
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition Journal article
Phytomedicine, 2022,Volume: 96
Authors:  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Senapati, Sanjib;  Malampati, Sandeep;  Zhu, Zhou;  Su, Cheng Fu;  Liu, Jia;  Guan, Xin Jie;  Tong, Benjamin Chun Kit;  Cheung, King Ho;  Tan, Jie Qiong;  Lu, Jia Hong;  Durairajan, Siva Sundara Kumar;  Song, Ju Xian;  Li, Min
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2022/03/04
3xtg-ad Mice  Alzheimer's Disease  Hdac6  P301s-tau Mice  Phospho-tau  Protopine  
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy Journal article
Acta Pharmacologica Sinica, 2022
Authors:  Zhu, Zhou;  Liu, Liang feng;  Su, Cheng fu;  Liu, Jia;  Tong, Benjamin Chun Kit;  Iyaswamy, Ashok;  Krishnamoorthi, Senthilkumar;  Sreenivasmurthy, Sravan Gopalkrishnashetty;  Guan, Xin jie;  Kan, Yu xuan;  Xie, Wen jian;  Zhao, Chen liang;  Cheung, King ho;  Lu, Jia hong;  Tan, Jie qiong;  Zhang, Hong jie;  Song, Ju xian;  Li, Min
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
Autophagy  Corynoxine b  Dopaminergic Neuron  Mpp++++  Oxindole Alkaloid  Parkinson’s Disease  Pi3p  Pik3c3 Complex  
Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review Journal article
Biomedicine and Pharmacotherapy, 2021,Volume: 133
Authors:  Wang,Zi Ying;  Liu,Jia;  Zhu,Zhou;  Su,Cheng Fu;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Iyaswamy,Ashok;  Lu,Jia Hong;  Chen,Gang;  Song,Ju Xian;  Li,Min
Favorite |  | TC[WOS]:11 TC[Scopus]:12 | Submit date:2021/03/02
Autophagy  Neurodegenerative Disease  Neuroprotection  Traditional Chinese Medicine  
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation Journal article
Autophagy, 2020,Volume: 17,Issue: 5,Page: 1112-1130
Authors:  Cai,Cui Zan;  Yang,Chuanbin;  Zhuang,Xu Xu;  Yuan,Ning Ning;  Wu,Ming Yue;  Tan,Jie Qiong;  Song,Ju Xian;  Cheung,King Ho;  Su,Huanxing;  Wang,Yi Tao;  Tang,Bei Sha;  Behrends,Christian;  Durairajan,Siva Sundara Kumar;  Yue,Zhenyu;  Li,Min;  Lu,Jia Hong
Favorite |  | TC[WOS]:12 TC[Scopus]:13 | Submit date:2021/03/01
Amaturation  Autophagy  Ccz1-mon1a  Nrbf2  Pi3kc3  Rab7  Trafficking  Vps34  
Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models Journal article
Cell Death and Disease, 2020,Volume: 11,Issue: 2
Authors:  Zhuang,Xu Xu;  Wang,Sheng Fang;  Tan,Yuan;  Song,Ju Xian;  Zhu,Zhou;  Wang,Zi Ying;  Wu,Ming Yue;  Cai,Cui Zan;  Huang,Zhi Jian;  Tan,Jie Qiong;  Su,Huan Xing;  Li,Min;  Lu,Jia Hong
Favorite |  | TC[WOS]:37 TC[Scopus]:37 | Submit date:2021/03/01
Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies Journal article
Autophagy, 2020,Volume: 16,Issue: 2,Page: 195-202
Authors:  Dong,Yu;  Hu,Yuanjia;  Sarkar,Sovan;  Zong,Wei Xing;  Li,Min;  Feng,Du;  Song,Ju Xian;  Li,Min;  Medina,Diego L.;  Tan,Jieqiong;  Zhang,Zhuohua;  Yue,Zhenyu;  Lu,Jia Hong
Favorite |  | TC[WOS]:8 TC[Scopus]:8 | Submit date:2021/03/01
Autophagy Modulator  Autophagy Modulator Scoring System  Autophagy-monitoring Methods  Co-citation Network  Methodology  
A small molecule transcription factor EB activator ameliorates beta-amyloid precursor protein and Tau pathology in Alzheimer's disease models Journal article
Aging Cell, 2020,Volume: 19,Issue: 2
Authors:  Song,Ju Xian;  Malampati,Sandeep;  Zeng,Yu;  Durairajan,Siva Sundara Kumar;  Yang,Chuan Bin;  Tong,Benjamin Chun Kit;  Iyaswamy,Ashok;  Shang,Wen Bin;  Sreenivasmurthy,Sravan Gopalkrishnashetty;  Zhu,Zhou;  Cheung,King Ho;  Lu,Jia Hong;  Tang,Chunzhi;  Xu,Nenggui;  Li,Min
Favorite |  | TC[WOS]:47 TC[Scopus]:49 | Submit date:2021/03/02
Alzheimer's Disease  Beta-amyloid  Curcumin Analog C1  Mapt/tau  Tfeb  
Targeting Aggrephagy for the Treatment of Alzheimer's Disease Journal article
Cells, 2020,Volume: 9,Issue: 2
Authors:  Malampati, Sandeep;  Song, Ju Xian;  Chun-Kit Tong, Benjamin;  Nalluri, Anusha;  Yang, Chuan Bin;  Wang, Ziying;  Gopalkrishnashetty Sreenivasmurthy, Sravan;  Zhu, Zhou;  Liu, Jia;  Su, Chengfu;  Krishnamoorthi, Senthilkumar;  Iyaswamy, Ashok;  Cheung, King Ho;  Lu, Jia Hong;  Li, And Min
Favorite |  | TC[WOS]:14 TC[Scopus]:14 | Submit date:2021/12/03
Aggregates  Aggrephagy  Alzheimer’s Disease  Selective Autophagy