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Identification of deleterious variants of uncertain significance in BRCA2 BRC4 repeat through molecular dynamics simulations Journal article
Briefings in functional genomics, 2022,Volume: 21,Issue: 3,Page: 202-215
Authors:  Sinha, Siddharth;  Qin, Zixin;  Tam, Benjamin;  Wang, San Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/06/10
Brca2 Brc4  Auc  Deleterious  Molecular Dynamics Simulations  Pca  Roc  Tolerated  Vus Classification  
Rbd double mutations of sars-cov-2 strains increase transmissibility through enhanced interaction between rbd and ace2 receptor Journal article
Viruses, 2022,Volume: 14,Issue: 1
Authors:  Sinha, Siddharth;  Tam, Benjamin;  Wang, San Ming
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2022/02/21
Antibody Escape  Free Energy  Md Simulations  Mm/gbsa  Sars-cov-2  Variants  
Comprehensive identification of deleterious TP53 missense VUS variants based on their impact on TP53 structural stability Journal article
International Journal of Molecular Sciences, 2021,Volume: 22,Issue: 21
Authors:  Tam, Benjamin;  Sinha, Siddharth;  Qin, Zixin;  Wang, San Ming
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/12/08
Deleterious  Molecular Dynamic Simulations  Ramachandran Plot  Tp53  Vus  
Prevalence and spectrum of DNA mismatch repair gene variation in the general Chinese population Journal article
Journal of Medical Genetics, 2021
Authors:  Zhang, Li;  Qin, Zixin;  Huang, Teng;  Tam, Benjamin;  Ruan, Yongsen;  Guo, Maoni;  Wu, Xiaobing;  Li, Jiaheng;  Zhao, Bojin;  Chian, Jia Sheng;  Wang, Xiaoyu;  Wang, Lei;  Wang, San Ming
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/05/13
Dna Repair  Genetic Variation  Genetics  Genomic Instability  Human Genetics  Population  
Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model Journal article
Computational and Structural Biotechnology Journal, 2020,Volume: 18,Page: 4033-4039
Authors:  Tam,Benjamin;  Sinha,Siddharth;  Wang,San Ming
Favorite |  | TC[WOS]:7 TC[Scopus]:6 | Submit date:2021/03/02
Molecular Dynamic Simulation  Pathogenic  Protein Structure  Ramachandran Plot  Tp53  Variant Of Uncertain Significance