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TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2
Journal article
Acta Pharmacologica Sinica, 2022,Volume: 43,Issue: 5,Page: 1251-1263
Authors:
Yang, Chuan bin
;
Liu, Jia
;
Tong, Benjamin Chun Kit
;
Wang, Zi ying
;
Zhu, Zhou
;
Su, Cheng fu
;
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Wu, Jia xi
;
Iyaswamy, Ashok
;
Krishnamoorthi, Senthilkumar
;
Huang, Shi ying
;
Cheung, King ho
;
Song, Ju xian
;
Tan, Jie qiong
;
Lu, Jia hong
;
Li, Min
Favorite
|
|
TC[WOS]:
1
TC[Scopus]:
2
|
Submit date:2022/05/13
15-deoxy-∆-12,14-prostaglandin J2 (15d-PGJ2)
apoptosis
ATF4
autophagy and lysosome biogenesis
ER stress
transcriptional factor EB (TFEB)
Protopine promotes the proteasomal degradation of pathological tau in Alzheimer's disease models via HDAC6 inhibition
Journal article
Phytomedicine, 2022,Volume: 96
Authors:
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Iyaswamy, Ashok
;
Krishnamoorthi, Senthilkumar
;
Senapati, Sanjib
;
Malampati, Sandeep
;
Zhu, Zhou
;
Su, Cheng Fu
;
Liu, Jia
;
Guan, Xin Jie
;
Tong, Benjamin Chun Kit
;
Cheung, King Ho
;
Tan, Jie Qiong
;
Lu, Jia Hong
;
Durairajan, Siva Sundara Kumar
;
Song, Ju Xian
;
Li, Min
Favorite
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TC[WOS]:
0
TC[Scopus]:
3
|
Submit date:2022/03/04
3xtg-ad Mice
Alzheimer's Disease
Hdac6
P301s-tau Mice
Phospho-tau
Protopine
Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy
Journal article
Acta Pharmacologica Sinica, 2022
Authors:
Zhu, Zhou
;
Liu, Liang feng
;
Su, Cheng fu
;
Liu, Jia
;
Tong, Benjamin Chun Kit
;
Iyaswamy, Ashok
;
Krishnamoorthi, Senthilkumar
;
Sreenivasmurthy, Sravan Gopalkrishnashetty
;
Guan, Xin jie
;
Kan, Yu xuan
;
Xie, Wen jian
;
Zhao, Chen liang
;
Cheung, King ho
;
Lu, Jia hong
;
Tan, Jie qiong
;
Zhang, Hong jie
;
Song, Ju xian
;
Li, Min
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
|
Submit date:2022/05/17
autophagy
corynoxine B
dopaminergic neuron
MPP+
oxindole alkaloid
Parkinson’s disease
PI3P
PIK3C3 complex
Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models
Journal article
Phytomedicine, 2021,Volume: 87
Authors:
Zhu, Qi
;
Zhuang, Xu xu
;
Chen, Jia yue
;
Yuan, Ning ning
;
Chen, Yan
;
Cai, Cui zan
;
Tan, Jie qiong
;
Su, Huan xing
;
Lu, Jia hong
Favorite
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TC[WOS]:
2
TC[Scopus]:
1
|
Submit date:2021/12/08
Camp/pka Pathway
Lycorine
Parkinson's Disease
Ubiquitin-proteasome System
Α-synuclein
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation
Journal article
Autophagy, 2020,Volume: 17,Issue: 5,Page: 1112-1130
Authors:
Cai,Cui Zan
;
Yang,Chuanbin
;
Zhuang,Xu Xu
;
Yuan,Ning Ning
;
Wu,Ming Yue
;
Tan,Jie Qiong
;
Song,Ju Xian
;
Cheung,King Ho
;
Su,Huanxing
;
Wang,Yi Tao
;
Tang,Bei Sha
;
Behrends,Christian
;
Durairajan,Siva Sundara Kumar
;
Yue,Zhenyu
;
Li,Min
;
Lu,Jia Hong
Favorite
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TC[WOS]:
9
TC[Scopus]:
12
|
Submit date:2021/03/01
Amaturation
Autophagy
Ccz1-mon1a
Nrbf2
Pi3kc3
Rab7
Trafficking
Vps34
Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models
Journal article
Cell Death and Disease, 2020,Volume: 11,Issue: 2
Authors:
Zhuang,Xu Xu
;
Wang,Sheng Fang
;
Tan,Yuan
;
Song,Ju Xian
;
Zhu,Zhou
;
Wang,Zi Ying
;
Wu,Ming Yue
;
Cai,Cui Zan
;
Huang,Zhi Jian
;
Tan,Jie Qiong
;
Su,Huan Xing
;
Li,Min
;
Lu,Jia Hong
Favorite
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TC[WOS]:
34
TC[Scopus]:
34
|
Submit date:2021/03/01
Natural alkaloid harmine promotes degradation of alpha-synuclein via PKA-mediated ubiquitin-proteasome system activation
Journal article
Phytomedicine, 2019,Volume: 61
Authors:
Cai,Cui Zan
;
Zhou,He Feng
;
Yuan,Ning Ning
;
Wu,Ming Yue
;
Lee,Simon Ming Yuen
;
Ren,Jiao Yan
;
Su,Huan Xing
;
Lu,Jin Jian
;
Chen,Xiu Ping
;
Li,Min
;
Tan,Jie Qiong
;
Lu,Jia Hong
Favorite
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TC[WOS]:
15
TC[Scopus]:
17
|
Submit date:2021/03/01
-synuclein
Harmine
Parkinson's Disease
Protein Kinase a
Ubiquitin-proteasome System
High content screening for drug discovery from traditional Chinese medicine
Journal article
Chinese Medicine (United Kingdom), 2019,Volume: 14,Issue: 1
Authors:
Wang,Jing
;
Wu,Ming Yue
;
Tan,Jie Qiong
;
Li,Min
;
Lu,Jia Hong
Favorite
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TC[WOS]:
11
TC[Scopus]:
11
|
Submit date:2021/03/02
Advanced Models
Drug Discovery
High-content Screening
Progressive Instruments
Traditional Chinese Medicine
Canthin-6-One Accelerates Alpha-Synuclein Degradation by Enhancing UPS Activity: Drug Target Identification by CRISPR-Cas9 Whole Genome-Wide Screening Technology
Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:
Ning-Ning Yuan
;
Cui-Zan Cai
;
Ming-Yue Wu
;
Qi Zhu
;
HuanXing Su
;
Min Li
;
JiaoYan Ren
;
Jie-Qiong Tan
;
Jia-Hong Lu
Favorite
|
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TC[WOS]:
9
TC[Scopus]:
12
|
Submit date:2020/04/14
Canthin-6-one
Parkinson’s Disease
Alpha-synuclein
Ubiquitin-proteasome-system
Crispr/cas9
Rpn2/psmd1
Pka
Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity
Journal article
ONCOTARGET, 2017,Volume: 8,Issue: 44,Page: 77673-77684
Authors:
Wu, Ming-Yue
;
Wang, Sheng-Fang
;
Cai, Cui-Zan
;
Tan, Jie-Qiong
;
Li, Min
;
Lu, Jin-Jian
;
Chen, Xiu-Ping
;
Wang, Yi-Tao
;
Zheng, Wei
;
Lu, Jia-Hong
Favorite
|
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TC[WOS]:
19
TC[Scopus]:
19
|
Submit date:2018/10/30
Dauricine
Daurisoline
Autophagy Blocker
Cancer Cells
Cell Toxicity