UM

Browse/Search Results:  1-10 of 16 Help

Selected(0)Clear Items/Page:    Sort:
Epigenetics of the Immune Component of Inflammation Journal article
Frontiers in Immunology, 2022
Authors:  Liu, Yan-Jun;  Wang, Haitao;  Zhong, Hai-Jing;  Chong, Cheong-Meng;  Yang, Guan-Jun
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/12
Highly Site- and Enantioselective N—H Functionalization of N-Monosubstituted Aniline Derivatives Affording Pyrazolones Bearing a Quaternary Stereocenter Journal article
Chinese Journal of Chemistry, 2022,Volume: 40,Issue: 10,Page: 1144-1148
Authors:  Wang, Guan Jun;  Zhang, Shu Yu;  Sun, Zhen Liang;  Li, Peng;  Ding, Tong Mei
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/13
Alkylation  Asymmetric Synthesis  Enantioselectivity  Nitrogen Heterocycles  Quaternary Stereocenter  
Inhibition of the CDK9–cyclin T1 protein–protein interaction as a new approach against triple-negative breast cancer Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1390-1405
Authors:  Cheng, Sha Sha;  Qu, Yuan Qing;  Wu, Jia;  Yang, Guan Jun;  Liu, Hao;  Wang, Wanhe;  Huang, Qi;  Chen, Feng;  Li, Guodong;  Wong, Chun Yuen;  Wong, Vincent Kam Wai;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2022/04/06
Epigenetics  Kinase Inhibitor  Metal Complex  Metastasis  Protein–protein Interaction  Triple-negative Breast Cancer  
A small molecule HIF-1α stabilizer that accelerates diabetic wound healing Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Li, Guodong;  Ko, Chung Nga;  Li, Dan;  Yang, Chao;  Wang, Wanhe;  Yang, Guan Jun;  Di Primo, Carmelo;  Wong, Vincent Kam Wai;  Xiang, Yaozu;  Lin, Ligen;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:17 TC[Scopus]:21 | Submit date:2021/12/09
An optimized BRD4 inhibitor effectively eliminates NF-κB-driven triple-negative breast cancer cells Journal article
Bioorganic Chemistry, 2021,Volume: 114
Authors:  Yang, Guan Jun;  Song, Ying Qi;  Wang, Wanhe;  Han, Quan Bin;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/08
Acetylated Rela  Brd4  Nf-κb  Protein-protein Interaction  Tnbc  
Discovery of a tetrahydroisoquinoline-based CDK9-cyclin T1 protein–protein interaction inhibitor as an anti-proliferative and anti-migration agent against triple-negative breast cancer cells Journal article
Genes and Diseases, 2021
Authors:  Cheng, Shasha;  Yang, Guan Jun;  Wang, Wanhe;  Ma, Dik Lung;  Leung, Chung Hang
Favorite |  | TC[WOS]:0 TC[Scopus]:3 | Submit date:2022/05/13
Cancer Stem Cells  Cdk9-cyclin T1  Epithelial Mesenchymal Transition  Protein–protein Interaction (Ppi)  Triple-negative Breast Cancer (Tnbc)  
A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy Journal article
International Journal of Biological Macromolecules, 2020,Volume: 164,Page: 3204-3220
Authors:  Yang,Guan Jun;  Wang,Wanhe;  Lei,Pui Man;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/01
Brd4  BromoDomain Domain  Cell Metastasis And Invasion  Histone Acetylation  Melanoma  Protein–protein Interaction  Virtual Screening  
Confirmative Structural Annotation for Metabolites of (R)-7,3′-Dihydroxy-4′-methoxy-8-methylflavane, A Natural Sweet Taste Modulator, by Liquid Chromatography-Three-Dimensional Mass Spectrometry Journal article
Journal of Agricultural and Food Chemistry, 2020,Volume: 68,Issue: 44,Page: 12454-12466
Authors:  Pengwei, Guan;  Song, Qingqing;  Li, Ting;  Cao, Libo;  Tang, Huiting;  Wang, Yitao;  Tu, Pengfei;  Zheng, Jiao;  Song, Yuelin;  Li, Jun
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/09/13
(r)-8-methyl-4′-methoxyl-7,3′-dihydroxylflavane  Flavonoids  Online Energy-resolved Mass Spectrometry  Optimal Collision Energy  Regio-isomers  
Erratum: The design and development of covalent protein-protein interaction inhibitors for cancer treatment (Journal of Hematology and Oncology (2020) 13 (26) DOI: 10.1186/s13045-020-00850-0) Other
2020-07-24
Authors:  Cheng, Sha Sha;  Yang, Guan Jun;  Wang, Wanhe;  Leung, Chung Hang;  Ma, Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2021/12/06
The design and development of covalent protein-protein interaction inhibitors for cancer treatment Journal article
Journal of Hematology and Oncology, 2020,Volume: 13,Issue: 1
Authors:  Cheng,Sha Sha;  Yang,Guan Jun;  Wang,Wanhe;  Leung,Chung Hang;  Ma,Dik Lung
Favorite |  | TC[WOS]:0 TC[Scopus]:27 | Submit date:2021/03/01
Cancer Therapy  Covalent Inhibitors  Protein-protein Interaction