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Impairment of the autophagy–lysosomal pathway in Alzheimer's diseases: Pathogenic mechanisms and therapeutic potential Journal article
Acta Pharmaceutica Sinica B, 2022,Volume: 12,Issue: 3,Page: 1019-1040
Authors:  Zhang, Wei;  Xu, Chengchao;  Sun, Jichao;  Shen, Han Ming;  Wang, Jigang;  Yang, Chuanbin
Favorite |  | TC[WOS]:2 TC[Scopus]:5 | Submit date：2022/04/06
Alzheimer's Disease (Ad)  Amyloid Beta (Aβ) Peptides  Autophagy  Autophagy Enhancers  Autophagy–lysosomal Pathway  Mapt/tau  Mitophagy  Neurodegenerative Diseases  
O-GlcNAcylation promotes fatty acid synthase activity under nutritional stress as a pro-survival mechanism in cancer cells Journal article
Proteomics, 2022,Volume: 22,Issue: 9
Authors:  Wong, Yin Kwan;  Wang, Jigang;  Lim, Teck Kwang;  Lin, Qingsong;  Yap, Celestial T.;  Shen, Han Ming
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/13
Fatty Acid Synthase  Itraq  Liquid Chromatography – Tandem Mass Spectrometry  Metabolic Labelling  O-glcnac  
The role of melatonin in the treatment of type 2 diabetes mellitus and Alzheimer’s disease Journal article
International Journal of Biological Sciences, 2022,Volume: 18,Issue: 3,Page: 983-994
Authors:  Shen, Shengnan;  Liao, Qiwen;  Wong, Yin Kwan;  Chen, Xiao;  Yang, Chuanbin;  Xu, Chengchao;  Sun, Jichao;  Wang, Jigang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/17
Alzheimer’s Disease  Anti-inflammatory  Insulin Resistance  Melatonin  Mitochondria  Type 2 Diabetes  
Modulation of Atg genes expression in aged rat liver, brain, and kidney by caloric restriction analyzed via single-nucleus/cell RNA sequencing Journal article
Autophagy, 2022
Authors:  Yang, Chuanbin;  Xia, Siyu;  Zhang, Wei;  Shen, Han Ming;  Wang, Jigang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/07/20
Aging  Atgs  Autophagy  Brain  Caloric Restriction (Cr)  Kidney  Liver  Longevity  Single-cell Rna Sequencing  
Modulation of Atg genes expression in aged rat liver, brain, and kidney by caloric restriction analyzed via single-nucleus/cell RNA sequencing Other
2022-01-01
Authors:  Yang, Chuanbin;  Xia, Siyu;  Zhang, Wei;  Shen, Han Ming;  Wang, Jigang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/08/05
Aging  ATGs  autophagy  brain  caloric restriction (CR)  kidney  liver  longevity  single-cell RNA sequencing  
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1 Journal article
Acta Pharmaceutica Sinica B, 2021
Authors:  Luo, Piao;  Liu, Dandan;  Zhang, Qian;  Yang, Fan;  Wong, Yin Kwan;  Xia, Fei;  Zhang, Junzhe;  Chen, Jiayun;  Tian, Ya;  Yang, Chuanbin;  Dai, Lingyun;  Shen, Han Ming;  Wang, Jigang
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date：2022/05/17
Abpp  Anti-oxidant  Celastrol  Ferroptosis  Hepatic Fibrosis  Ho-1  Peroxiredoxin  Reactive Oxygen Species  
Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy Journal article
Acta Pharmaceutica Sinica B, 2021
Authors:  Tang, Yancheng;  Wang, Liming;  Yi, Tao;  Xu, Jun;  Wang, Jigang;  Qin, Jiang Jiang;  Chen, Qilei;  Yip, Ka Man;  Pan, Yihang;  Hong, Peng;  Lu, Yingying;  Shen, Han Ming;  Chen, Hu Biao
Favorite |  | TC[WOS]:0 TC[Scopus]:3 | Submit date：2021/11/30
Apoptosis  Combination Therapy  Magnolol  Pink1‒parkin-mediated Mitophagy  Tumor Suppression