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Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models
Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:
Zhou,Hefeng
;
Shao,Min
;
Guo,Baojian
;
Li,Chuwen
;
Lu,Yucong
;
Yang,Xuanjun
;
ShengnanLi,
;
Li,Haitao
;
Zhu,Qi
;
Zhong,Hanbing
;
Wang,Yuqiang
;
Zhang,Zaijun
;
Lu,Jiahong
;
Lee,Simon Ming Yuen
Favorite
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TC[WOS]:
7
TC[Scopus]:
7
|
Submit date:2021/03/01
Degradation
LMP7
Parkinson’s disease
Proteasome activity
α-synuclein
A Danshensu-Tetramethylpyrazine Conjugate DT-010 Overcomes Multidrug Resistance in Human Breast Cancer
Journal article
FRONTIERS IN PHARMACOLOGY, 2019,Volume: 10
Authors:
Xinhua Zhou
;
Anqi Wang
;
Liang Wang
;
Jianhua Yin
;
Li Wang
;
Lijun Di
;
Maggie Pui-Man Hoi
;
Luchen Shan
;
Xu Wu
;
Yuqiang Wang
Favorite
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TC[WOS]:
3
TC[Scopus]:
4
|
Submit date:2020/05/21
Danshensu
Tetramethylpyrazine
Breast Cancer
Resistance
Glycolysis
P-glycoprotein
Memantine improves cognitive function and alters hippocampal and cortical proteome in triple transgenic mouse model of Alzheimer’s disease
Journal article
Experimental Neurobiology, 2019,Volume: 28,Issue: 3,Page: 390-403
Authors:
Zhou,Xinhua
;
Wang,Liang
;
Xiao,Wei
;
Su,Zhiyang
;
Zheng,Chengyou
;
Zhang,Zaijun
;
Wang,Yuqiang
;
Xu,Benhong
;
Yang,Xifei
;
Hoi,Maggie Pui Man
Favorite
|
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TC[WOS]:
7
TC[Scopus]:
6
|
Submit date:2021/03/01
Alzheimer’s disease (AD)
MARK2
Memantine
Proteomic
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo
Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:
Zhou,Hefeng
;
Shao,Min
;
Yang,Xuanjun
;
Li,Chuwen
;
Cui,Guozhen
;
Gao,Cheng
;
Di,Lijun
;
Zhong,Hanbing
;
Wang,Yuqiang
;
Zhang,Zaijun
;
Lee,Simon Ming Yuen
Favorite
|
|
TC[WOS]:
5
TC[Scopus]:
5
|
Submit date:2021/03/01
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice
Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:
Guozhen Cui
;
Qiqi Xin
;
Hisa Hui Ling Tseng
;
Maggie PuiMan Hoi
;
Yan Wang
;
Binrui Yang
;
InLeng Choi
;
Yuqiang Wang
;
Rong Yuan
;
Keji Chen
;
Weihong Cong
;
Simon MingYuen Lee
Favorite
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TC[WOS]:
5
TC[Scopus]:
5
|
Submit date:2020/01/16
Cardioprotection
Angiogenesis
Adtm
Zebrafish
Vegf
A novel Ca2+ current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice
Journal article
PHARMACOLOGICAL RESEARCH, 2018,Volume: 134,Page: 109-117
Authors:
Cui, Guozhen
;
Xin, Qiqi
;
Tseng, Hisa Hui Ling
;
Hoi, Maggie PuiMan
;
Wang, Yan
;
Yang, Binrui
;
Choi, InLeng
;
Wang, Yuqiang
;
Yuan, Rong
;
Chen, Keji
;
Cong, Weihong
;
Lee, Simon MingYuen
View
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Favorite
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TC[WOS]:
5
TC[Scopus]:
5
|
Submit date:2018/10/30
Cardioprotection
Angiogenesis
ADTM
Zebrafish
VEGF
A Novel Tetramethylpyrazine Derivative Prophylactically Protects against Glutamate-Induced Excitotoxicity in Primary Neurons through the Blockage of N-Methyl-D-aspartate Receptor
Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:
Hu, Shengquan
;
Hu, Huihui
;
Mak, Shinghung
;
Cui, Guozhen
;
Lee, Mingyuen
;
Shan, Luchen
;
Wang, Yuqiang
;
Lin, Huangquan
;
Zhang, Zaijun
;
Han, Yifan
Favorite
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TC[WOS]:
8
TC[Scopus]:
9
|
Submit date:2018/10/30
Alzheimer's disease
tetramethylpyrazine derivative
NMDA receptor
neuroprotection
oxidative stress
GSK3 beta
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B
Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:
Guo, Baojian
;
Hu, Shengquan
;
Zheng, Chengyou
;
Wang, Hongyu
;
Luo, Fangcheng
;
Li, Haitao
;
Cui, Wei
;
Yang, Xifei
;
Cui, Guozhen
;
Mak, Shinghung
;
Choi, Tony Chung-Lit
;
Ma, Edmond Dik-Lung
;
Wang, Yuqiang
;
Lee, Simon Ming Yuen
;
Zhang, Zaijun
;
Han, Yifan
View
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Adobe PDF
|
Favorite
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TC[WOS]:
13
TC[Scopus]:
14
|
Submit date:2018/10/31
Parkinson's disease
SU4312
Neuroprotection
Myocyte enhancer factor 2D
Monoamine oxidase-B
Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-B
Journal article
NEUROPHARMACOLOGY, 2017,Volume: 126,Page: 12-24
Authors:
Guo, Baojian
;
Hu, Shengquan
;
Zheng, Chengyou
;
Wang, Hongyu
;
Luo, Fangcheng
;
Li, Haitao
;
Cui, Wei
;
Yang, Xifei
;
Cui, Guozhen
;
Mak, Shinghung
;
Choi, Tony Chung-Lit
;
Ma, Edmond Dik-Lung
;
Wang, Yuqiang
;
Lee, Simon Ming Yuen
;
Zhang, Zaijun
;
Han, Yifan
Favorite
|
|
TC[WOS]:
13
TC[Scopus]:
14
|
Submit date:2018/10/30
Parkinson's disease
SU4312
Neuroprotection
Myocyte enhancer factor 2D
Monoamine oxidase-B
Characterization of the Molecular Mechanisms Underlying the Chronic Phase of Stroke in a Cynomolgus Monkey Model of Induced Cerebral Ischemia
Journal article
JOURNAL OF PROTEOME RESEARCH, 2017,Volume: 16,Issue: 3,Page: 1150-1166
Authors:
Law, Henry C. H.
;
Szeto, Samuel S. W.
;
Quan, Quan
;
Zhao, Yun
;
Zhang, Zaijun
;
Krakovska, Olga
;
Lui, Leong Ting
;
Zheng, Chengyou
;
Lee, Simon M. -Y.
;
Siu, K. W. Michael
;
Wang, Yuqiang
;
Chu, Ivan K.
Favorite
|
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TC[WOS]:
8
TC[Scopus]:
8
|
Submit date:2018/10/30
Stroke Biology
Itraq
Cynomolgus Monkey
Brain Proteome
Ischemia
Chronic Phase