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| Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors: Huang，Mu Yang; Jiang，Xiao Ming; Wang，Bing Lin; Sun，Yang; Lu，Jin Jian
  Favorite | | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/03/02
challenge combination therapy immunotherapy mechanism NSCLC PD-1/PD-L1 |
| Combination therapy with PD-1/PD-L1 blockade in non-small cell lung cancer: strategies and mechanisms Journal article
Pharmacology and Therapeutics, 2021,Volume: 219
Authors: Huang，Mu Yang; Jiang，Xiao Ming; Wang，Bing Lin; Sun，Yang; Lu，Jin Jian
Favorite | | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/03/02
challenge combination therapy immunotherapy mechanism NSCLC PD-1/PD-L1 |
| Licochalcone A inhibits interferon-gamma-induced programmed death-ligand 1 in lung cancer cells Journal article
Phytomedicine, 2021,Volume: 80
Authors: Yuan，Luo Wei; Jiang，Xiao Ming; Xu，Yu Lian; Huang，Mu Yang; Chen，Yu Chi; Yu，Wei Bang; Su，Min Xia; Ye，Zi Han; Chen，Xiuping ; Wang，Yitao; Lu，Jin Jian
Favorite | | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/03/01
IFN-γ Licochalcone A Natural products PD-L1 Protein synthesis inhibitor ROS |
| Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors: CHEN，Yu Chi; HUANG，Mu Yang; ZHANG，Le Le; FENG，Zhe Ling; JIANG，Xiao Ming; YUAN，Luo Wei; HUANG，Run Yue; LIU，Bo; YU，Hua; WANG，Yi Tao; CHEN，Xiu Ping; LIN，Li Gen; LU，Jin Jian
Favorite | | TC[WOS]:2 TC[Scopus]:2 | Submit date：2021/03/01
c-Jun JNK Lung cancer Nagilactone E Programmed death ligand 1 |
| Adsorption of Pb(II) from aqueous solution by polyacrylic acid grafted magnetic chitosan nanocomposite Journal article
International Journal of Biological Macromolecules, 2020,Volume: 154,Page: 1537-1547
Authors: Hu，Dalin; Lian，Zhenwei; Xian，Hongyi; Jiang，Ran; Wang，Nan; Weng，Yingying; Peng，Xiaowu; Wang，Sanming; Ouyang，Xiao–Kun –K
Favorite | | TC[WOS]:10 TC[Scopus]:13 | Submit date：2021/03/02
Acidity resistance Chitosan Polyacrylic acid |
| Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity Journal article
Acta Pharmacologica Sinica, 2020,Volume: 41,Issue: 5,Page: 698-705
Authors: Zhang，Le le; Guo，Jing; Jiang，Xiao ming; Chen，Xiu ping; Wang，Yi tao; Li，Ao; Lin，Li gen; Li，Hua; Lu，Jin jian
Favorite | | TC[WOS]:6 TC[Scopus]:6 | Submit date：2021/03/01
Click-iT CMap diterpenoids human lung cancer A549 cell line xenograft molecular docking nagilactone E protein synthesis inhibitor RIOK2 RNA-seq |
| Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Biochemical Pharmacology, 2020,Volume: 175
Authors: Li，Ting; Xu，Xiao Huang; Guo，Xia; Yuan，Tao; Tang，Zheng Hai; Jiang，Xiao Ming; Xu，Yu Lian; Zhang，Le Le; Chen，Xiuping; Zhu，Hong; Shi，Jia Jie; Lu，Jin Jian
Favorite | | TC[WOS]:2 TC[Scopus]:3 | Submit date：2021/03/01
Apoptosis c-MYC CHOP Lung cancer Notch 3 |
| Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2020,Volume: 20,Issue: 8,Page: 982-988
Authors: Zhang，Le Le; Bao，Han; Xu，Yu Lian; Jiang，Xiao Ming; Li，Wei; Zou，Liang; Lin，Li Gen; Lu，Jin Jian
Favorite | | TC[WOS]:1 TC[Scopus]:2 | Submit date：2021/03/01
Anti-cancer Autophagy C-Jun JNK Non-small cell lung cancer Phanginin R |
| TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020
Authors: Jiang，Xiao ming; Xu，Yu lian; Yuan，Luo wei; Zhang，Le le; Huang，Mu yang; Ye，Zi han; Su，Min xia; Chen，Xiu ping; Zhu，Hong; Ye，Richard D.; Lu，Jin jian
Favorite | | TC[WOS]:3 TC[Scopus]:2 | Submit date：2021/03/01
EGFR mutant non-small cell lung cancer epithelial-mesenchymal transition NF-κB osimertinib resistance TGFβ2 |
| Small molecule IVQ, as a prodrug of gluconeogenesis inhibitor QVO, efficiently ameliorates glucose homeostasis in type 2 diabetic mice Journal article
ACTA PHARMACOLOGICA SINICA, 2019,Volume: 40,Issue: 9,Page: 1193-1204
Authors: Ting-ting Zhou; Tong Zhao; Fei Ma; Yi-nan Zhang; Jing Jiang; Yuan Ruan; Qiu-ying Yan; Gai-hong Wang; Jin Ren; Xiao-wei Guan; Jun Guo; Yong-hua Zhao; Ji-ming Ye; Li-hong Hu; Jing Chen; Xu Shen
Favorite | | TC[WOS]:1 TC[Scopus]:2 | Submit date：2020/04/14
Type 2 Diabetes Mellitus Hepatic Gluconeogenesis Ampk Signaling Pathway (e)-3-(2-(Quinoline-4-yl)Vinyl)-1h-indol-6-ol (Qvo) 4-[2-(1h-indol-3-yl)Vinyl]Quinoline (Ivq) Prodrug |
