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S100A9-CXCL12 activation in BRCA1-mutant breast cancer promotes an immunosuppressive microenvironment associated with resistance to immunotherapy Journal article
Nature Communications, 2022,Volume: 13,Issue: 1
Authors:  Li, Jianjie;  Shu, Xiaodong;  Xu, Jun;  Su, Sek Man;  Chan, Un In;  Mo, Lihua;  Liu, Jianlin;  Zhang, Xin;  Adhav, Ragini;  Chen, Qiang;  Wang, Yuqing;  An, Tingting;  Zhang, Xu;  Lyu, Xueying;  Li, Xiaoling;  Lei, Josh Haipeng;  Miao, Kai;  Sun, Heng;  Xing, Fuqiang;  Zhang, Aiping;  Deng, Chuxia;  Xu, Xiaoling
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/13
ATP11B inhibits breast cancer metastasis in a mouse model by suppressing externalization of nonapoptotic phosphatidylserine Journal article
Journal of Clinical Investigation, 2022,Volume: 132,Issue: 5
Authors:  Xu, Jun;  Su, Sek Man;  Zhang, Xin;  Chan, Un In;  Adhav, Ragini;  Shu, Xiaodong;  Liu, Jianlin;  Li, Jianjie;  Mo, Lihua;  Wang, Yuqing;  An, Tingting;  Lei, Josh Haipeng;  Miao, Kai;  Deng, Chu Xia;  Xu, Xiaoling
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/03/28
Single-cell analysis reveals androgen receptor regulates the ER-to-Golgi trafficking pathway with CREB3L2 to drive prostate cancer progression Journal article
Oncogene, 2021,Volume: 40,Issue: 47,Page: 6479-6493
Authors:  Hu, Lingling;  Chen, Xin;  Narwade, Nitin;  Lim, Michelle Gek Liang;  Chen, Zikai;  Tennakoon, Chandana;  Guan, Peiyong;  Chan, Un In;  Zhao, Zuxianglan;  Deng, Mokan;  Xu, Xiaoling;  Sung, Wing Kin;  Cheung, Edwin
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/12/08
Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy Journal article
Advanced Science, 2021,Volume: 8,Issue: 21
Authors:  Lei, Josh Haipeng;  Lee, Mi Hye;  Miao, Kai;  Huang, Zebin;  Yao, Zhicheng;  Zhang, Aiping;  Xu, Jun;  Zhao, Ming;  Huang, Zenan;  Zhang, Xin;  Chen, Si;  Jiaying, N. G.;  Feng, Yuzhao;  Xing, Fuqiang;  Chen, Ping;  Sun, Heng;  Chen, Qiang;  Xiang, Tingxiu;  Chen, Lin;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/11/30
Brca1  Breast Cancer  Fgfr2 Inhibitor  Fgfr2-s252w  Tumor Slice Culture  
Patient-Derived Organoids Can Guide Personalized-Therapies for Patients with Advanced Breast Cancer Journal article
Advanced Science, 2021,Volume: 8,Issue: 22
Authors:  Chen, Ping;  Zhang, Xu;  Ding, Renbo;  Yang, Linglin;  Lyu, Xueying;  Zeng, Jianming;  Lei, Josh Haipeng;  Wang, Lijian;  Bi, Jiong;  Shao, Nan;  Shu, Ditian;  Wu, Bin;  Wu, Jingbo;  Yang, Zhihui;  Wang, Haiyan;  Wang, Biqiong;  Xiong, Kang;  Lu, Yun;  Fu, Shaozhi;  Choi, Tak Kan;  Lon, Ng Wai;  Zhang, Aiping;  Tang, Dongyang;  Quan, Yingyao;  Meng, Ya;  Miao, Kai;  Sun, Heng;  Zhao, Ming;  Bao, Jiaolin;  Zhang, Lei;  Xu, Xiaoling;  Shi, Yanxia;  Lin, Ying;  Deng, Chuxia
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date：2021/11/30
Advanced Breast Cancer  Drug Screening  Patient-derived Organoids  Personalized Therapy  
Sirt1 deficiency upregulates glutathione metabolism to prevent hepatocellular carcinoma initiation in mice Journal article
Oncogene, 2021,Volume: 40,Issue: 41,Page: 6023-6033
Authors:  Qiu, Pengxiang;  Hou, Weilong;  Wang, Haitao;  Lei, Kimmy Ka Wing;  Wang, Shaowei;  Chen, Weiping;  Pardeshi, Lakhansing Arun;  Prothro, Katherine;  Shukla, Yashvita;  Su, Samson Sek Man;  Schrump, David S.;  Chen, Qiang;  Deng, Chu Xia;  Xu, Xiaoling;  Wang, Ruihong
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/12/08
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Ding, Ren Bo;  Chen, Ping;  Rajendran, Barani Kumar;  Lyu, Xueying;  Wang, Haitao;  Bao, Jiaolin;  Zeng, Jianming;  Hao, Wenhui;  Sun, Heng;  Wong, Ada Hang Heng;  Valecha, Monica Vishnu;  Yang, Eun Ju;  Su, Sek Man;  Choi, Tak Kan;  Liu, Shuiming;  Chan, Kin Iong;  Yang, Ling Lin;  Wu, Jingbo;  Miao, Kai;  Chen, Qiang;  Shim, Joong Sup;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date：2021/11/30
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing Journal article
Theranostics, 2021,Volume: 11,Issue: 20,Page: 9967-9987
Authors:  Sun, Heng;  Zeng, Jianming;  Miao, Zhengqiang;  Lei, Kuan Cheok;  Huang, Chen;  Hu, Lingling;  Su, Sek Man;  Chan, Un In;  Miao, Kai;  Zhang, Xu;  Zhang, Aiping;  Guo, Sen;  Chen, Si;  Meng, Ya;  Deng, Min;  Hao, Wenhui;  Lei, Haipeng;  Lin, Ying;  Yang, Zhonglin;  Tang, Dongjiang;  Wong, Koon Ho;  Zhang, Xiaohua Douglas;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/11/30
Brca1/BRCA1  Mammary tumor  Mrc2  Single cell RNA-seq  Tumor heterogeneity  
Accelerating precision anti-cancer therapy by time-lapse and label-free 3D tumor slice culture platform Journal article
Theranostics, 2021,Volume: 11,Issue: 19,Page: 9415-9430
Authors:  Xing, Fuqiang;  Liu, Yu Cheng;  Huang, Shigao;  Lyu, Xueying;  Su, Sek Man;  Chan, Un In;  Wu, Pei Chun;  Yan, Yinghan;  Ai, Nana;  Li, Jianjie;  Zhao, Ming;  Rajendran, Barani Kumar;  Liu, Jianlin;  Shao, Fangyuan;  Sun, Heng;  Choi, Tak Kan;  Zhu, Wenli;  Luo, Guanghui;  Liu, Shuiming;  Xu, De Li;  Chan, Kin Long;  Zhao, Qi;  Miao, Kai;  Luo, Kathy Qian;  Ge, Wei;  Xu, Xiaoling;  Wang, Guanyu;  Liu, Tzu Ming;  Deng, Chu Xia
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/11/30
3D tumor slice culture  Apoptosis  FRET technique  Label-free  Personalized medicine  
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:8 TC[Scopus]:7 | Submit date：2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ