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Discovery of a naturally occurring broad-spectrum inhibitor against gut bacterial β-glucuronidases from: Ginkgo biloba Journal article
Food and Function, 2021,Volume: 12,Issue: 22,Page: 11190-11201
Authors:  Bai, Yue;  Chen, Lu;  Wang, Pan Pan;  Tang, Yu Qiang;  Wu, Da Chang;  Zhang, Cui Li;  Zhou, Qi;  Yan, Ru;  Hou, Jie
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date:2021/12/08
Fecal multi-omics analysis reveals diverse molecular alterations of gut ecosystem in COVID-19 patients Journal article
Analytica Chimica Acta, 2021,Volume: 1180
Authors:  He, Feixiang;  Zhang, Ting;  Xue, Kewen;  Fang, Zhaoxiong;  Jiang, Guanmin;  Huang, Siwen;  Li, Kexue;  Gu, Zhiqiang;  Shi, Honggang;  Zhang, Zhenyi;  Zhu, Huijin;  Lin, Lu;  Li, Jialin;  Xiao, Fei;  Shan, Hong;  Yan, Ru;  Li, Xiaofeng;  Yan, Zhixiang
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2021/12/08
Covid-19  Glycoproteomics  Gut Microbiome  Metabolomics  Metaproteomics  
Human gut bacterial β-glucuronidase inhibition: An emerging approach to manage medication therapy Journal article
Biochemical Pharmacology, 2021,Volume: 190
Authors:  Wang, Panpan;  Jia, Yifei;  Wu, Rongrong;  Chen, Zhiqiang;  Yan, Ru
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date:2021/12/08
Bacterial Β-glucuronidases  Drug Metabolism  Efficacy/toxicity  Inhibition  
Structural characterization and transcript-metabolite correlation network of immunostimulatory effects of sulfated polysaccharides from green alga Ulva pertusa Journal article
Food Chemistry, 2021,Volume: 342
Authors:  Han,Yu;  Wu,Yulin;  Li,Guoqiang;  Li,Meiying;  Yan,Ru;  Xu,Zhenlin;  Lei,Hongtao;  Sun,Yuanming;  Duan,Xuewu;  Hu,Lianmei;  Huang,Riming
Favorite |  | TC[WOS]:7 TC[Scopus]:8 | Submit date:2021/03/01
Immunostimulatory Activity  Polysaccharide  Structural Characteristics  Ulva Pertusa  
Dextran sulfate sodium-induced colitis and ginseng intervention altered oral pharmacokinetics of cyclosporine A in rats Journal article
Journal of Ethnopharmacology, 2021,Volume: 265
Authors:  Yang,Ying;  Hu,Nan;  Gao,Xue Jiao;  Li,Ting;  Yan,Zhi Xiang;  Wang,Pan Pan;  Wei,Bin;  Li,Sai;  Zhang,Zai Jun;  Li,Song Lin;  Yan,Ru
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
Cyclosporine a  Experimental Colitis  Ginseng  Gut Microbiota  Oral Pharmacokinetics  Tight Junction  
A semi-tryptic peptide centric metaproteomic mining approach and its potential utility in capturing signatures of gut microbial proteolysis Journal article
Microbiome, 2021,Volume: 9,Issue: 1
Authors:  Yan, Zhixiang;  He, Feixiang;  Xiao, Fei;  He, Huanhuan;  Li, Dan;  Cong, Li;  Lin, Lu;  Zhu, Huijin;  Wu, Yanyan;  Yan, Ru;  Li, Xiaofeng;  Shan, Hong
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/12/07
Gut Microbial Proteolysis  Inflammatory Bowel Disease  Metaproteomics  
Size effect of curcumin nanocrystals on dissolution, airway mucosa penetration, lung tissue distribution and absorption by pulmonary delivery Journal article
Colloids and Surfaces B: Biointerfaces, 2020,Volume: 186
Authors:  He,Yuan;  Liang,Yingmin;  Mak,Judith Choi Wo;  Liao,Yonghong;  Li,Ting;  Yan,Ru;  Li,Hai Feng;  Zheng,Ying
Favorite |  | TC[WOS]:9 TC[Scopus]:11 | Submit date:2021/03/01
Förster Resonance Energy Transfer (Fret)  Lung Absorption  Nanocrystals  Pulmonary Delivery  Size Effect  
Characteristics and molecular determinants of a highly selective and efficient glycyrrhizin-hydrolyzing beta-glucuronidase from Staphylococcus pasteuri 3I10 Journal article
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2018,Volume: 102,Issue: 21,Page: 9193-9205
Authors:  Wei, Bin;  Wang, Pan-Pan;  Yan, Zhi-Xiang;  Yan, Ru
Favorite |  | TC[WOS]:13 TC[Scopus]:13 | Submit date:2019/01/17
Staphylococcus pasteuri  Bacterial beta-glucuronidase  Glycyrrhizin  Glycyrrhetinic acid  Deglucuronidation  Homology modeling  
Prenylflavonoids sanggenon C and kuwanon G from mulberry (Morus alba L.) as potent broad-spectrum bacterial β-glucuronidase inhibitors: Biological evaluation and molecular docking studies Journal article
Journal of Functional Foods, 2018,Volume: 48,Page: 210-219
Authors:  Wei,Bin;  Yang,Wei;  Yan,Zhi Xiang;  Zhang,Qing Wen;  Yan,Ru
Favorite |  | TC[WOS]:15 TC[Scopus]:16 | Submit date:2021/03/01
Human Gut Microbiota  Kuwanon g  Molecular Docking  Sanggenon c  Β-glucuronidase Inhibitor  
Pharmacokinetics of Chinese medicines: strategies and perspectives Journal article
CHINESE MEDICINE, 2018,Volume: 13
Authors:  Yan, Ru;  Yang, Ying;  Chen, Yijia
Favorite |  | TC[WOS]:14 TC[Scopus]:18 | Submit date:2018/10/30
Chinese Medicines  Pharmacokinetic Strategy  Pharmacokinetics-pharmacodynamics Relevance  Gut Microbiota  Global Pharmacokinetics-pharmacodynamics