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Single-cell analyses reveal mechanisms of cancer stem cell maintenance and epithelial-mesenchymal transition in recurrent bladder cancer Journal article
Clinical Cancer Research, 2021,Volume: 27,Issue: 22,Page: 6265-6278
Authors:  Wang, Huanjun;  Mei, Yan;  Luo, Cheng;  Huang, Qun;  Wang, Zifeng;  Lu, Guan Ming;  Qin, Lili;  Sun, Zhun;  Huang, Chao Wen;  Yang, Zhi Wen;  Chen, Junxing;  Yin, Weiguo;  Qian, Chao Nan;  Zeng, Jianming;  Chen, Lingwu;  Leng, Qibin;  Guo1, Yan;  Jia, Guangshuai
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date：2021/12/08
Patient-Derived Organoids Can Guide Personalized-Therapies for Patients with Advanced Breast Cancer Journal article
Advanced Science, 2021,Volume: 8,Issue: 22
Authors:  Chen, Ping;  Zhang, Xu;  Ding, Renbo;  Yang, Linglin;  Lyu, Xueying;  Zeng, Jianming;  Lei, Josh Haipeng;  Wang, Lijian;  Bi, Jiong;  Shao, Nan;  Shu, Ditian;  Wu, Bin;  Wu, Jingbo;  Yang, Zhihui;  Wang, Haiyan;  Wang, Biqiong;  Xiong, Kang;  Lu, Yun;  Fu, Shaozhi;  Choi, Tak Kan;  Lon, Ng Wai;  Zhang, Aiping;  Tang, Dongyang;  Quan, Yingyao;  Meng, Ya;  Miao, Kai;  Sun, Heng;  Zhao, Ming;  Bao, Jiaolin;  Zhang, Lei;  Xu, Xiaoling;  Shi, Yanxia;  Lin, Ying;  Deng, Chuxia
Favorite |  | TC[WOS]:3 TC[Scopus]:6 | Submit date：2021/11/30
Advanced Breast Cancer  Drug Screening  Patient-derived Organoids  Personalized Therapy  
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics Journal article
Nature Communications, 2021,Volume: 12,Issue: 1
Authors:  Ding, Ren Bo;  Chen, Ping;  Rajendran, Barani Kumar;  Lyu, Xueying;  Wang, Haitao;  Bao, Jiaolin;  Zeng, Jianming;  Hao, Wenhui;  Sun, Heng;  Wong, Ada Hang Heng;  Valecha, Monica Vishnu;  Yang, Eun Ju;  Su, Sek Man;  Choi, Tak Kan;  Liu, Shuiming;  Chan, Kin Iong;  Yang, Ling Lin;  Wu, Jingbo;  Miao, Kai;  Chen, Qiang;  Shim, Joong Sup;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date：2021/11/30
Dissecting the heterogeneity and tumorigenesis of BRCA1 deficient mammary tumors via single cell RNA sequencing Journal article
Theranostics, 2021,Volume: 11,Issue: 20,Page: 9967-9987
Authors:  Sun, Heng;  Zeng, Jianming;  Miao, Zhengqiang;  Lei, Kuan Cheok;  Huang, Chen;  Hu, Lingling;  Su, Sek Man;  Chan, Un In;  Miao, Kai;  Zhang, Xu;  Zhang, Aiping;  Guo, Sen;  Chen, Si;  Meng, Ya;  Deng, Min;  Hao, Wenhui;  Lei, Haipeng;  Lin, Ying;  Yang, Zhonglin;  Tang, Dongjiang;  Wong, Koon Ho;  Zhang, Xiaohua Douglas;  Xu, Xiaoling;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/11/30
Brca1/BRCA1  Mammary tumor  Mrc2  Single cell RNA-seq  Tumor heterogeneity  
Cullin3 deficiency shapes tumor microenvironment and promotes cholangiocarcinoma in liver-specific smad4/pten mutant mice Journal article
International Journal of Biological Sciences, 2021,Volume: 17,Issue: 15,Page: 4176-4191
Authors:  Zhao, Ming;  Quan, Yingyao;  Zeng, Jianming;  Lyu, Xueying;  Wang, Haitao;  Lei, Josh Haipeng;  Feng, Yangyang;  Xu, Jun;  Chen, Qiang;  Sun, Heng;  Xu, Xiaoling;  Lu, Ligong;  Deng, Chu Xia
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2022/05/13
Anti-pd1/pd-l1 Therapy  Cholangiocarcinoma  Exhausted t Cells  Inflammatory Cytokines  Tumor Microenvironment  
Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
Favorite |  | TC[WOS]:2 TC[Scopus]:2 | Submit date：2021/03/02
Aib1  Ecm  Hedgehog  Mafb  Pdac  
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:11 TC[Scopus]:11 | Submit date：2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
CDR3 sequences in IgA nephropathy are shorter and exhibit reduced diversity Journal article
FEBS Open Bio, 2020,Volume: 10,Issue: 12,Page: 2702-2711
Authors:  Zhang, Xi;  Zeng, Jianming;  Tong, Yin;  Zhang, Li;  Lu, Xibin;  Zhu, Shenglang;  Li, Zhoufang
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/12/06
Cdr3 Length  Iga  Iga Nephropathy  Igg  Igm  
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
Favorite |  | TC[WOS]:14 TC[Scopus]:17 | Submit date：2021/03/02
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:25 TC[Scopus]:27 | Submit date：2020/09/16