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Upregulation of amplified in breast cancer 1 contributes to pancreatic ductal adenocarcinoma progression and vulnerability to blockage of hedgehog activation Journal article
Theranostics, 2021,Volume: 11,Issue: 4,Page: 1672-1689
Authors:  Li,Licen;  Bao,Jiaolin;  Wang,Haitao;  Lei,Josh Haipeng;  Peng,Cheng;  Zeng,Jianming;  Hao,Wenhui;  Zhang,Xu;  Xu,Xiaoling;  Yu,Chundong;  Deng,Chu Xia;  Chen,Qiang
Favorite |  | TC[WOS]:1 TC[Scopus]:0 | Submit date：2021/03/02
Aib1  Ecm  Hedgehog  Mafb  Pdac  
Cisplatin prevents breast cancer metastasis through blocking early EMT and retards cancer growth together with paclitaxel Journal article
Theranostics, 2021,Volume: 11,Issue: 5,Page: 2442-2459
Authors:  Wang,Haitao;  Guo,Sen;  Kim,Seung Jin;  Shao,Fangyuan;  Kei Ho,Joshua Wing;  Wong,Kuan Un;  Miao,Zhengqiang;  Hao,Dapeng;  Zhao,Ming;  Xu,Jun;  Zeng,Jianming;  Wong,Koon Ho;  Di,Lijun;  Wong,Ada Hang Heng;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date：2021/03/02
Cisplatin  Metastasis  Neoadjuvant Therapy  Paclitaxel  Tgfβ  
NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Miao,Kai;  Lei,Josh Haipeng;  Valecha,Monica Vishnu;  Zhang,Aiping;  Xu,Jun;  Wang,Lijian;  Lyu,Xueying;  Chen,Si;  Miao,Zhengqiang;  Zhang,Xin;  Su,Sek Man;  Shao,Fangyuan;  Rajendran,Barani Kumar;  Bao,Jiaolin;  Zeng,Jianming;  Sun,Heng;  Chen,Ping;  Tan,Kaeling;  Chen,Qiang;  Wong,Koon Ho;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:6 TC[Scopus]:5 | Submit date：2020/09/16
Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor Journal article
Nature Communications, 2020,Volume: 11,Issue: 1
Authors:  Liu,Jianlin;  Adhav,Ragini;  Miao,Kai;  Su,Sek Man;  Mo,Lihua;  Chan,Un In;  Zhang,Xin;  Xu,Jun;  Li,Jianjie;  Shu,Xiaodong;  Zeng,Jianming;  Zhang,Xu;  Lyu,Xueying;  Pardeshi,Lakhansing;  Tan,Kaeling;  Sun,Heng;  Wong,Koon Ho;  Deng,Chuxia;  Xu,Xiaoling
Favorite |  | TC[WOS]:3 TC[Scopus]:4 | Submit date：2021/03/02
EZH2 overexpression dampens tumor-suppressive signals via an EGR1 silencer to drive breast tumorigenesis Journal article
Oncogene, 2020,Volume: 39,Issue: 48,Page: 7127-7141
Authors:  Guan,Xiaowen;  Deng,Houliang;  Choi,Un Lam;  Li,Zhengfeng;  Yang,Yiqi;  Zeng,Jianming;  Liu,Yunze;  Zhang,Xuanjun;  Li,Gang
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date：2021/03/04
Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation Journal article
EPIGENETICS & CHROMATIN, 2019,Volume: 12
Authors:  Ting Zhang;  Xiaowen Guan;  Un Lam Choi;  Qiang Dong;  Melody M. T. Lam;  Jianming Zeng;  Jun Xiong;  Xianju Wang;  Terence C. W. Poon;  Hongjie Zhang;  Xuanjun Zhang;  Hailin Wang;  Ruiyu Xie;  Bing Zhu;  Gang Li
Favorite |  | TC[WOS]:11 TC[Scopus]:12 | Submit date：2020/05/26
Ampk  Tet2  Phosphorylation  Myogenesis  Pax7  
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-G374R mutation in achondroplasia in mice Journal article
Journal of Biological Chemistry, 2019,Volume: 294,Issue: 4,Page: 1142-1151
Authors:  Miao,Kai;  Zhang,Xin;  Su,Sek Man;  Zeng,Jianming;  Huang,Zebin;  Chan,Un In;  Xu,Xiaoling;  Deng,Chu Xia
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date：2020/09/16
CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer Journal article
SCIENTIFIC REPORTS, 2019,Volume: 9
Authors:  Houliang Deng;  Xiaowen Guan;  Longcai Gong;  Jianming Zeng;  Hongjie Zhang;  Mike Y. Chen;  Gang Li
Favorite |  | TC[WOS]:10 TC[Scopus]:11 | Submit date：2020/06/22
Optimizing CRISPR/Cas9 technology for precise correction of the Fgfr3-Gly374Arg mutation in achondroplasia in mice Journal article
The Journal of Biological Chemistry, 2018
Authors:  Kai Miao;  Xin Zhang;  Sek Man Su;  Jianming Zeng;  Zebin Huang;  Un In Chan;  Xiaoling Xu;  Chu-Xia Deng
Favorite |  | TC[WOS]:5 TC[Scopus]:5 | Submit date：2018/12/17
Fgfr3  Crispr/cas9  Protein  Targeted Correction  Off-target  Achondroplasia  Dwarfism  Genome Editing  Gene Therapy  
Histone H3.3K27M Mobilizes Multiple Cancer/Testis (CT) Antigens in Pediatric Glioma Journal article
MOLECULAR CANCER RESEARCH, 2018,Volume: 16,Issue: 4,Page: 623-633
Authors:  Deng, Houliang;  Zeng, Jianming;  Zhang, Ting;  Gong, Longcai;  Zhang, Hongjie;  Cheung, Edwin;  Jones, Chris;  Li, Gang
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date：2018/10/30