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Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics Journal article
Food Chemistry, 2020,Volume: 327
Authors:  Zhang,Le Le;  Huang,Mu Yang;  Yang,Yong;  Huang,Ming Qing;  Shi,Jia Jie;  Zou,Liang;  Lu,Jin Jian
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Pharmacokinetics  Pharmacological Activities  Phytochemistry  Platycodins  Platycodonis Radix  Toxicology  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming;  YUAN,Luo Wei;  HUANG,Run Yue;  LIU,Bo;  YU,Hua;  WANG,Yi Tao;  CHEN,Xiu Ping;  LIN,Li Gen;  LU,Jin Jian
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C-jun  Jnk  Lung Cancer  Nagilactone e  Programmed Death Ligand 1  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Biochemical Pharmacology, 2020,Volume: 175
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai;  Jiang,Xiao Ming;  Xu,Yu Lian;  Zhang,Le Le;  Chen,Xiuping;  Zhu,Hong;  Shi,Jia Jie;  Lu,Jin Jian
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Apoptosis  C-myc  Chop  Lung Cancer  Notch 3  
Identification of nagilactone E as a protein synthesis inhibitor with anticancer activity Journal article
Acta Pharmacologica Sinica, 2020,Volume: 41,Issue: 5,Page: 698-705
Authors:  Zhang,Le le;  Guo,Jing;  Jiang,Xiao ming;  Chen,Xiu ping;  Wang,Yi tao;  Li,Ao;  Lin,Li gen;  Li,Hua;  Lu,Jin jian
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Click-it  Cmap  Diterpenoids  Human Lung Cancer A549 Cell Line Xenograft  Molecular Docking  Nagilactone e  Protein Synthesis Inhibitor  Riok2  Rna-seq  
Ruthenium-Catalyzed Direct Asymmetric Reductive Amination of Diaryl and Sterically Hindered Ketones with Ammonium Salts and H2 Journal article
Angewandte Chemie - International Edition, 2020,Volume: 59,Issue: 13,Page: 5321-5325
Authors:  Hu，Le' an;  Zhang，Yao;  Zhang，Qing Wen;  Yin，Qin;  Zhang，Xumu
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amines  diaryl ketones  homogeneous catalysis  reductive amination  ruthenium  
Nagilactone D ameliorates experimental pulmonary fibrosis in vitro and in vivo via modulating TGF-β/Smad signaling pathway Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 389
Authors:  Li,Ao;  Xiao,Xiao;  Feng,Zhe Ling;  Chen,Xiuping;  Liu,Li Juan;  Lin,Li Gen;  Lu,Jin Jian;  Zhang,Le Le
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Bleomycin  Fibrotic Process  Nagilactone d  Pulmonary Fibrosis  Tgf-β1  
Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2020,Volume: 20,Issue: 8,Page: 982-988
Authors:  Zhang,Le Le;  Bao,Han;  Xu,Yu Lian;  Jiang,Xiao Ming;  Li,Wei;  Zou,Liang;  Lin,Li Gen;  Lu,Jin Jian
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Anti-cancer  Autophagy  C-jun  Jnk  Non-small Cell Lung Cancer  Phanginin r  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
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Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation Journal article
Autophagy, 2020
Authors:  Wu，Ming Yue;  Liu，Le;  Wang，Er Jin;  Xiao，Hai Tao;  Cai，Cui Zan;  Wang，Jing;  Su，Huanxing;  Wang，Yitao;  Tan，Jieqiong;  Zhang，Zhuohua;  Wang，Juan;  Yao，Maojing;  Ouyang，De Fang;  Yue，Zhenyu;  Li，Min;  Chen，Ye;  Bian，Zhao Xiang;  Lu，Jia Hong
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Apoptotic cell clearance  inflammatory bowel disease  macrophage  MON1-CCZ1  NRBF2  RAB7  
CuH-Catalyzed Atropoenantioselective Reduction of Bringmann's Lactones via Dynamic Kinetic Resolution Journal article
Organic Letters, 2019,Volume: 21,Issue: 14,Page: 5575-5580
Authors:  Hu，Le'An;  Zhang，Yao;  Chen，Gen Qiang;  Lin，Bi Jin;  Zhang，Qing Wen;  Yin，Qin;  Zhang，Xumu
Favorite |  | TC[WOS]:8 TC[Scopus]:9 | Submit date：2021/03/02