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Natural constituents from food sources as therapeutic agents for obesity and metabolic diseases targeting adipose tissue inflammation Journal article
Critical Reviews in Food Science and Nutrition, 2021,Volume: 61,Issue: 12,Page: 1947-1965
Authors:  Li,Dan;  Zhang,Tian;  Lu,Jinjian;  Peng,Cheng;  Lin,Ligen
Favorite |  | TC[WOS]:12 TC[Scopus]:7 | Submit date:2021/03/01
Adipocytes  Adipose Tissue Inflammation  Crosstalk  Dietary Bioactive Nutrients  Macrophages  Metabolic Disease  
Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth Journal article
Signal Transduction and Targeted Therapy, 2020,Volume: 5,Issue: 1
Authors:  Yao,Nan;  Wang,Chen Ran;  Liu,Ming Qun;  Li,Ying Jie;  Chen,Wei Min;  Li,Zheng Qiu;  Qi,Qi;  Lu,Jin Jian;  Fan,Chun Lin;  Chen,Min Feng;  Qi,Ming;  Li,Xiao Bo;  Hong,Jian;  Zhang,Dong Mei;  Ye,Wen Cai
Favorite |  | TC[WOS]:4 TC[Scopus]:3 | Submit date:2021/03/02
Anti-proliferative cassane-type diterpenoids from the seeds of Caesalpinia minax Journal article
Natural Product Research, 2020
Authors:  Xu,Yunshao;  Shi,Wei;  Feng,Lu;  Cao,Jun;  Feng,Zheling;  Zhang,Qingwen;  Lu,Jinjian;  Ye,Yang;  Lin,Ligen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/01
Caesalpinia Minax  Cassane Diterpenoids  Cytotoxic Activity  Fabaceae  
Bioactive platycodins from Platycodonis Radix: Phytochemistry, pharmacological activities, toxicology and pharmacokinetics Journal article
Food Chemistry, 2020,Volume: 327
Authors:  Zhang,Le Le;  Huang,Mu Yang;  Yang,Yong;  Huang,Ming Qing;  Shi,Jia Jie;  Zou,Liang;  Lu,Jin Jian
Favorite |  | TC[WOS]:12 TC[Scopus]:14 | Submit date:2021/03/02
Pharmacokinetics  Pharmacological Activities  Phytochemistry  Platycodins  Platycodonis Radix  Toxicology  
Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3 Journal article
Toxicology and Applied Pharmacology, 2020,Volume: 404
Authors:  Liu,Xin;  Zhang,Yiying;  ZHOU,Guang Ju;  Hou,Ying;  Kong,Qi;  Lu,Jin Jian;  Zhang,Qingwen;  Chen,Xiuping
Favorite |  | TC[WOS]:2 TC[Scopus]:3 | Submit date:2021/03/01
8-oxo-epiberberine  Epithelial-mesenchymal Transition  Metastasis  Tgf-β1  
TGFβ2-mediated epithelial–mesenchymal transition and NF-κB pathway activation contribute to osimertinib resistance Journal article
Acta Pharmacologica Sinica, 2020,Volume: 42,Issue: 3,Page: 451-459
Authors:  Jiang,Xiao ming;  Xu,Yu lian;  Yuan,Luo wei;  Zhang,Le le;  Huang,Mu yang;  Ye,Zi han;  Su,Min xia;  Chen,Xiu ping;  Zhu,Hong;  Ye,Richard D.;  Lu,Jin jian
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Egfr Mutant Non-small Cell Lung Cancer  Epithelial-mesenchymal Transition  Nf-κb  Osimertinib Resistance  Tgfβ2  
Nagilactone E increases PD-L1 expression through activation of c-Jun in lung cancer cells Journal article
Chinese Journal of Natural Medicines, 2020,Volume: 18,Issue: 7,Page: 517-525
Authors:  CHEN,Yu Chi;  HUANG,Mu Yang;  ZHANG,Le Le;  FENG,Zhe Ling;  JIANG,Xiao Ming;  YUAN,Luo Wei;  HUANG,Run Yue;  LIU,Bo;  YU,Hua;  WANG,Yi Tao;  CHEN,Xiu Ping;  LIN,Li Gen;  LU,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:5 | Submit date:2021/03/01
C-jun  Jnk  Lung Cancer  Nagilactone e  Programmed Death Ligand 1  
Phanginin R induces cytoprotective autophagy via JNK/C-JUN signaling pathway in non-small cell lung cancer A549 cells Journal article
Anti-Cancer Agents in Medicinal Chemistry, 2020,Volume: 20,Issue: 8,Page: 982-988
Authors:  Zhang,Le Le;  Bao,Han;  Xu,Yu Lian;  Jiang,Xiao Ming;  Li,Wei;  Zou,Liang;  Lin,Li Gen;  Lu,Jin Jian
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/03/01
Anti-cancer  Autophagy  C-jun  Jnk  Non-small Cell Lung Cancer  Phanginin r  
Dual modulation of formyl peptide receptor 2 by aspirin-triggered lipoxin contributes to its anti-inflammatory activity Journal article
FASEB Journal, 2020,Volume: 34,Issue: 5,Page: 6920-6933
Authors:  Ge,Yunjun;  Zhang,Shuo;  Wang,Junlin;  Xia,Fangbo;  Wan,Jian Bo;  Lu,Jinjian;  Ye,Richard D.
Favorite |  | TC[WOS]:15 TC[Scopus]:14 | Submit date:2021/03/02
Biased Signaling  g Protein-coupled Receptor  Inflammation  Inverse Agonism  
Activation of notch 3/c-MYC/CHOP axis regulates apoptosis and promotes sensitivity of lung cancer cells to mTOR inhibitor everolimus Journal article
Biochemical Pharmacology, 2020,Volume: 175
Authors:  Li,Ting;  Xu,Xiao Huang;  Guo,Xia;  Yuan,Tao;  Tang,Zheng Hai;  Jiang,Xiao Ming;  Xu,Yu Lian;  Zhang,Le Le;  Chen,Xiuping;  Zhu,Hong;  Shi,Jia Jie;  Lu,Jin Jian
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/03/01
Apoptosis  C-myc  Chop  Lung Cancer  Notch 3