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Thyroid hormone enhances stem cell maintenance and promotes lineage-specific differentiation in human embryonic stem cells
Journal article
Stem Cell Research and Therapy, 2022,Volume: 13,Issue: 1
Authors:
Deng, Chunhao
;
Zhang, Zhaoying
;
Xu, Faxiang
;
Xu, Jiaqi
;
Ren, Zhili
;
Godoy-Parejo, Carlos
;
Xiao, Xia
;
Liu, Weiwei
;
Zhou, Zhou
;
Chen, Guokai
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/05/13
Cell Culture
Hpscs
Pluripotency
Thyroid Hormone
Triiodothyronine (T3)
Trophoblast
Insulin Directs Dichotomous Translational Regulation to Control Human Pluripotent Stem Cell Survival, Proliferation and Pluripotency
Journal article
International Journal of Biological Sciences, 2022,Volume: 18,Issue: 9,Page: 3562-3575
Authors:
Zhou, Xiaoxiao
;
Ren, Zhili
;
Xu, Jiaqi
;
Deng, Chunhao
;
Zhang, Zhaoying
;
Godoy-Parejo, Carlos
;
Xu, Faxiang
;
Huang, Esther Chi Cheng
;
Wang, Jiajia
;
Cai, Zheyu
;
Liu, Weiwei
;
Hu, Guang
;
Chen, Guokai
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2022/08/05
AKT
Cell Survival
eIF4E
Human pluripotent stem cell (hPSC)
Insulin
mTOR
NOXA/PMAIP1
Pluripotency
Proliferation
Translation
Nicotinamide promotes pancreatic differentiation through the dual inhibition of CK1 and ROCK kinases in human embryonic stem cells
Journal article
Stem Cell Research and Therapy, 2021,Volume: 12,Issue: 1
Authors:
Zhang, Yumeng
;
Xu, Jiaqi
;
Ren, Zhili
;
Meng, Ya
;
Liu, Weiwei
;
Lu, Ligong
;
Zhou, Zhou
;
Chen, Guokai
Favorite
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TC[WOS]:
5
TC[Scopus]:
5
|
Submit date:2021/12/09
Casein Kinase 1 (Ck1)
Human Embryonic Stem Cells
Kinase Inhibitor
Nicotinamide
Pancreatic Progenitors
Rho-associated Protein Kinase (Rock)
Nicotinamide promotes cardiomyocyte derivation and survival through kinase inhibition in human pluripotent stem cells
Journal article
Cell Death and Disease, 2021,Volume: 12,Issue: 12
Authors:
Meng, Ya
;
Song, Chengcheng
;
Ren, Zhili
;
Li, Xiaohong
;
Yang, Xiangyu
;
Ai, Nana
;
Yang, Yang
;
Wang, Dongjin
;
Zhan, Meixiao
;
Wang, Jiaxian
;
Lei, Chon Lok
;
Liu, Weiwei
;
Ge, Wei
;
Lu, Ligong
;
Chen, Guokai
Favorite
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2021/12/08
Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
Journal article
Cell Reports, 2021,Volume: 37,Issue: 9
Authors:
Xu, Faxiang
;
Deng, Chunhao
;
Ren, Zhili
;
Sun, Liangyu
;
Meng, Ya
;
Liu, Weiwei
;
Wan, Jianbo
;
Chen, Guokai
Favorite
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TC[WOS]:
2
TC[Scopus]:
2
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Submit date:2021/12/08
cellular state
hPSC
lipid
LPA
metabolism
mitochondria
pluripotency
transcriptome
Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells
Journal article
Stem Cell Reports, 2020,Volume: 15,Issue: 6,Page: 1362-1376
Authors:
Ren,Zhili
;
Zhong,Hui
;
Song,Chengcheng
;
Deng,Chunhao
;
Hsieh,Hsun Ting
;
Liu,Weiwei
;
Chen,Guokai
Favorite
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TC[WOS]:
10
TC[Scopus]:
11
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Submit date:2021/03/02
Akt
Caspase
Cell Survival
Gsk3
Human Embryonic Stem Cells
Insulin
Mitochondrial Respiration
Novel venom-based peptides (P13 and its derivative - M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways
Journal article
Stem Cell Research and Therapy, 2020,Volume: 11,Issue: 1
Authors:
Ma,Rui
;
Ren,Zhili
;
Li,Bin
;
Siu,Shirley W.I.
;
Chen,Guokai
;
Kwok,Hang Fai
Favorite
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TC[WOS]:
2
TC[Scopus]:
2
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Submit date:2021/03/04
Embryonic Stem Cell
Peptide Modification
Pluripotency
Self-renewal
Venom Peptide
Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators
Journal article
International Journal of Biological Sciences, 2020,Volume: 16,Issue: 8,Page: 1450-1462
Authors:
Zhong,Hui
;
Ren,Zhili
;
Wang,Xiaoyan
;
Miao,Kai
;
Ni,Wenjun
;
Meng,Ya
;
Lu,Ligong
;
Wang,Chunming
;
Liu,Weiwei
;
Deng,Chu Xia
;
Xu,Ren He
;
Chen,Guokai
Favorite
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TC[WOS]:
4
TC[Scopus]:
4
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Submit date:2020/09/16
Defined Factors
Human Embryonic Stem Cells
Keratinocyte Differentiation
Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells
Journal article
Cell Reports, 2019,Volume: 29,Issue: 11,Page: 3374-3384.e5
Authors:
Yang,Yang
;
Ren,Zhili
;
Xu,Faxiang
;
Meng,Ya
;
Zhang,Yumeng
;
Ai,Nana
;
Long,Yan
;
Fok,Hio Ian
;
Deng,Chunhao
;
Zhao,Xianyang
;
Huang,Liancheng
;
Zhao,Qi
;
Wang,Jiaxian
;
Liu,Weiwei
;
Ge,Wei
;
Chen,Guokai
Favorite
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TC[WOS]:
8
TC[Scopus]:
9
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Submit date:2021/03/02
Cardiomyocyte
Casein Kinase Ii
Heterogeneity
Human Embryonic Stem Cells
Igf
Insulin
Mesoderm
Pi3k
Temporal Regulation
Wnt
Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells
Journal article
STEM CELL REPORTS, 2019,Volume: 13,Issue: 2,Page: 338-351
Authors:
Chengcheng Song
;
Faxiang Xu
;
Zhili Ren
;
Yumeng Zhang
;
Ya Meng
;
Yiqi Yang
;
Shreyas Lingadahalli
;
Edwin Cheung
;
Gang Li
;
Weiwei Liu
;
Jianbo Wan
;
Yang Zhao
;
Guokai Chen
Favorite
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TC[WOS]:
14
TC[Scopus]:
20
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Submit date:2020/04/22
Hescs
Pyruvate
Bmp4
Glycolysis
Tca Cycle
Ampk
Wnt
Metabolism
Mesoderm
Differentiation