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Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy
Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:
Yang, Guan-Jun
;
Wang, Wanhe
;
Mok, Simon Wing Fai
;
Wu, Chun
;
Law, Betty Yuen Kwan
;
Miao, Xiang-Min
;
Wu, Ke-Jia
;
Zhong, Hai-Jing
;
Wong, Chun-Yuen
;
Wong, Vincent Kam Wai
;
Ma, Dik-Lung
;
Leung, Chung-Hang
Favorite
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TC[WOS]:
47
TC[Scopus]:
50
|
Submit date:2018/10/30
Drug Discovery
Epigenetics
Medicinal Chemistry
Triple-negative Breast Cancer
Ultra-stretchable and highly sensitive strain sensor based on gradient structure carbon nanotubes
Journal article
NANOSCALE, 2018,Volume: 10,Issue: 28,Page: 13599-13606
Authors:
Liang, Binghao
;
Lin, Zhiqiang
;
Chen, Wenjun
;
He, Zhongfu
;
Zhong, Jing
;
Zhu, Hai
;
Tang, Zikang
;
Gui, Xuchun
Favorite
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TC[WOS]:
37
TC[Scopus]:
36
|
Submit date:2018/10/30
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells
Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:
Yang, Guan-Jun
;
Zhong, Hai-Jing
;
Ko, Chung-Nga
;
Wong, Suk-Yu
;
Vellaisamy, Kasipandi
;
Ye, Min
;
Ma, Dik-Lung
;
Leung, Chung-Hang
View
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Favorite
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TC[WOS]:
20
TC[Scopus]:
19
|
Submit date:2018/10/30
Cell imaging of dopamine receptor using agonist labeling iridium(III) complex
Journal article
CHEMICAL SCIENCE, 2018,Volume: 9,Issue: 5,Page: 1119-1125
Authors:
Vellaisamy, Kasipandi
;
Li, Guodong
;
Ko, Chung-Nga
;
Zhong, Hai-Jing
;
Fatima, Sarwat
;
Kwan, Hiu-Yee
;
Wong, Chun-Yuen
;
Kwong, Wai-Jing
;
Tan, Weihong
;
Leung, Chung-Hang
;
Ma, Dik-Lung
Favorite
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TC[WOS]:
89
TC[Scopus]:
88
|
Submit date:2018/10/30
Small Molecule Pin1 Inhibitor Blocking NF-B Signaling in Prostate Cancer Cells
Journal article
CHEMISTRY-AN ASIAN JOURNAL, 2018,Volume: 13,Issue: 3,Page: 275-279
Authors:
Wu, Ke-Jia
;
Zhong, Hai-Jing
;
Yang, Guanjun
;
Wu, Chun
;
Huang, Jie-Min
;
Li, Guodong
;
Ma, Dik-Lung
;
Leung, Chung-Hang
Favorite
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TC[WOS]:
22
TC[Scopus]:
23
|
Submit date:2018/10/30
Enzymes
Natural Products
Pin1
Protein-protein Interactions
Virtual Screening
Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing
Journal article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018,Volume: 143,Page: 1021-1027
Authors:
Wu, Ke-Jia
;
Zhong, Hai-Jing
;
Li, Guodong
;
Liu, Chenfu
;
Wang, Hui-Min David
;
Ma, Dik-Lung
;
Leung, Chung-Hang
Favorite
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TC[WOS]:
34
TC[Scopus]:
35
|
Submit date:2018/10/30
Drug Repurposing
Mitoxantrone
Nedd8
Ubiquitin
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-kappa B
Journal article
CANCER LETTERS, 2017,Volume: 396,Page: 76-84
Authors:
Kang, Tian-Shu
;
Wang, Wanhe
;
Zhong, Hai-Jing
;
Dong, Zhen-Zhen
;
Huang, Qi
;
Mok, Simon Wing Fai
;
Leung, Chung-Hang
;
Wong, Vincent Kam Wai
;
Ma, Dik-Lung
Favorite
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TC[WOS]:
47
TC[Scopus]:
48
|
Submit date:2018/10/30
Benzofuran-conjugated iridium(III) complex
STAT3
NF-kappa B
Prostate cells
Dual inhibitors
A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells
Journal article
PLOS ONE, 2017,Volume: 12,Issue: 6
Authors:
Wu, Ke-Jia
;
Huang, Jie-Min
;
Zhong, Hai-Jing
;
Dong, Zhen-Zhen
;
Vellaisamy, Kasipandi
;
Lu, Jin-Jian
;
Chen, Xiu-Ping
;
Chiu, Pauline
;
Kwong, Daniel W. J.
;
Han, Quan-Bin
;
Ma, Dik-Lung
;
Leung, Chung-Hang
Favorite
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TC[WOS]:
25
TC[Scopus]:
27
|
Submit date:2018/10/30
Anticancer osmium complex inhibitors of the HIF-1 alpha and p300 protein-protein interaction
Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:
Yang, Chao
;
Wang, Wanhe
;
Li, Guo-Dong
;
Zhong, Hai-Jing
;
Dong, Zhen-Zhen
;
Wong, Chun-Yuen
;
Kwong, Daniel W. J.
;
Ma, Dik-Lung
;
Leung, Chung-Hang
Favorite
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TC[WOS]:
16
TC[Scopus]:
23
|
Submit date:2018/10/30
A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity
Journal article
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2017,Volume: 1861,Issue: 2,Page: 256-263
Authors:
Kang, Tian-Shu
;
Wang, Wanhe
;
Zhong, Hai-Jing
;
Liang, Jia-Xin
;
Ko, Chung-Nga
;
Lu, Jin-Jian
;
Chen, Xiu-Ping
;
Ma, Dik-Lung
;
Leung, Chung-Hang
Favorite
|
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TC[WOS]:
15
TC[Scopus]:
20
|
Submit date:2018/10/30
Rhodium Complex
Anticancer
Melanoma
Autotaxin
Inhibitor