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Selective Inhibition of Lysine-Specific Demethylase 5A (KDM5A) Using a Rhodium(III) Complex for Triple-Negative Breast Cancer Therapy Journal article
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018,Volume: 57,Issue: 40,Page: 13091-13095
Authors:  Yang, Guan-Jun;  Wang, Wanhe;  Mok, Simon Wing Fai;  Wu, Chun;  Law, Betty Yuen Kwan;  Miao, Xiang-Min;  Wu, Ke-Jia;  Zhong, Hai-Jing;  Wong, Chun-Yuen;  Wong, Vincent Kam Wai;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:47 TC[Scopus]:50 | Submit date：2018/10/30
Drug Discovery  Epigenetics  Medicinal Chemistry  Triple-negative Breast Cancer  
Ultra-stretchable and highly sensitive strain sensor based on gradient structure carbon nanotubes Journal article
NANOSCALE, 2018,Volume: 10,Issue: 28,Page: 13599-13606
Authors:  Liang, Binghao;  Lin, Zhiqiang;  Chen, Wenjun;  He, Zhongfu;  Zhong, Jing;  Zhu, Hai;  Tang, Zikang;  Gui, Xuchun
Favorite |  | TC[WOS]:37 TC[Scopus]:36 | Submit date：2018/10/30
Identification of a rhodium(III) complex as a Wee1 inhibitor against TP53-mutated triple-negative breast cancer cells Journal article
CHEMICAL COMMUNICATIONS, 2018,Volume: 54,Issue: 20,Page: 2463-2466
Authors:  Yang, Guan-Jun;  Zhong, Hai-Jing;  Ko, Chung-Nga;  Wong, Suk-Yu;  Vellaisamy, Kasipandi;  Ye, Min;  Ma, Dik-Lung;  Leung, Chung-Hang
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Cell imaging of dopamine receptor using agonist labeling iridium(III) complex Journal article
CHEMICAL SCIENCE, 2018,Volume: 9,Issue: 5,Page: 1119-1125
Authors:  Vellaisamy, Kasipandi;  Li, Guodong;  Ko, Chung-Nga;  Zhong, Hai-Jing;  Fatima, Sarwat;  Kwan, Hiu-Yee;  Wong, Chun-Yuen;  Kwong, Wai-Jing;  Tan, Weihong;  Leung, Chung-Hang;  Ma, Dik-Lung
Favorite |  | TC[WOS]:89 TC[Scopus]:88 | Submit date：2018/10/30
Small Molecule Pin1 Inhibitor Blocking NF-B Signaling in Prostate Cancer Cells Journal article
CHEMISTRY-AN ASIAN JOURNAL, 2018,Volume: 13,Issue: 3,Page: 275-279
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Yang, Guanjun;  Wu, Chun;  Huang, Jie-Min;  Li, Guodong;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:22 TC[Scopus]:23 | Submit date：2018/10/30
Enzymes  Natural Products  Pin1  Protein-protein Interactions  Virtual Screening  
Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing Journal article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018,Volume: 143,Page: 1021-1027
Authors:  Wu, Ke-Jia;  Zhong, Hai-Jing;  Li, Guodong;  Liu, Chenfu;  Wang, Hui-Min David;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:34 TC[Scopus]:35 | Submit date：2018/10/30
Drug Repurposing  Mitoxantrone  Nedd8  Ubiquitin  
An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-kappa B Journal article
CANCER LETTERS, 2017,Volume: 396,Page: 76-84
Authors:  Kang, Tian-Shu;  Wang, Wanhe;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Huang, Qi;  Mok, Simon Wing Fai;  Leung, Chung-Hang;  Wong, Vincent Kam Wai;  Ma, Dik-Lung
Favorite |  | TC[WOS]:47 TC[Scopus]:48 | Submit date：2018/10/30
Benzofuran-conjugated iridium(III) complex  STAT3  NF-kappa B  Prostate cells  Dual inhibitors  
A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells Journal article
PLOS ONE, 2017,Volume: 12,Issue: 6
Authors:  Wu, Ke-Jia;  Huang, Jie-Min;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Vellaisamy, Kasipandi;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Chiu, Pauline;  Kwong, Daniel W. J.;  Han, Quan-Bin;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:25 TC[Scopus]:27 | Submit date：2018/10/30
Anticancer osmium complex inhibitors of the HIF-1 alpha and p300 protein-protein interaction Journal article
SCIENTIFIC REPORTS, 2017,Volume: 7
Authors:  Yang, Chao;  Wang, Wanhe;  Li, Guo-Dong;  Zhong, Hai-Jing;  Dong, Zhen-Zhen;  Wong, Chun-Yuen;  Kwong, Daniel W. J.;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:16 TC[Scopus]:23 | Submit date：2018/10/30
A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity Journal article
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2017,Volume: 1861,Issue: 2,Page: 256-263
Authors:  Kang, Tian-Shu;  Wang, Wanhe;  Zhong, Hai-Jing;  Liang, Jia-Xin;  Ko, Chung-Nga;  Lu, Jin-Jian;  Chen, Xiu-Ping;  Ma, Dik-Lung;  Leung, Chung-Hang
Favorite |  | TC[WOS]:15 TC[Scopus]:20 | Submit date：2018/10/30
Rhodium Complex  Anticancer  Melanoma  Autotaxin  Inhibitor