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Ginger polysaccharides relieve ulcerative colitis via maintaining intestinal barrier integrity and gut microbiota modulation Journal article
International Journal of Biological Macromolecules, 2022,Volume: 219,Page: 730-739
Authors:  Hao, Wei;  Chen, Zhejie;  Yuan, Qin;  Ma, Meiling;  Gao, Caifang;  Zhou, Yangyang;  Zhou, Hefeng;  Wu, Xu;  Wu, Dingtao;  Farag, Mohamed A.;  Wang, Shengpeng;  Wang, Yitao
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2022/11/07
Ginger  Polysaccharides  Ulcerative Colitis  
Targeted delivery of Chinese herb pair-based berberine/tannin acid self-assemblies for the treatment of ulcerative colitis Journal article
Journal of Advanced Research, 2021,Volume: 40,Page: 263-276
Authors:  Chen, Shiyun;  Chen, Zhejie;  Wang, Yi;  Hao, Wei;  Yuan, Qin;  Zhou, Hefeng;  Gao, Caifang;  Wang, Yitao;  Wu, Xu;  Wang, Shengpeng
Favorite |  | TC[WOS]:3 TC[Scopus]:3 | Submit date:2022/05/13
Berberine  Drug Delivery  Gut Microbiome  Tannin Acid  Ulcerative Colitis  
Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:  Zhou,Hefeng;  Li,Shengnan;  Li,Chuwen;  Yang,Xuanjun;  Li,Haitao;  Zhong,Hanbing;  Lu,Jia Hong;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:7 TC[Scopus]:7 | Submit date:2021/03/01
Parkinson's Disease  Α-synuclein  Degradation  Proteasome  Neuroprotection  
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:  Zhou,Hefeng;  Shao,Min;  Yang,Xuanjun;  Li,Chuwen;  Cui,Guozhen;  Gao,Cheng;  Di,Lijun;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:10 TC[Scopus]:11 | Submit date:2021/03/01
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:  Zhou,Hefeng;  Shao,Min;  Guo,Baojian;  Li,Chuwen;  Lu,Yucong;  Yang,Xuanjun;  ShengnanLi,;  Li,Haitao;  Zhu,Qi;  Zhong,Hanbing;  Wang,Yuqiang;  Zhang,Zaijun;  Lu,Jiahong;  Lee,Simon Ming Yuen
Favorite |  | TC[WOS]:15 TC[Scopus]:16 | Submit date:2021/03/01
Degradation  Lmp7  Parkinson’s Disease  Proteasome Activity  Α-synuclein  
A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019,Volume: 120,Issue: 4,Page: 5913-5922
Authors:  Ying Zhang;  Hongkuan Deng;  Hefeng Zhou;  Yucong Lu;  Luchen Shan;  Simon Ming‐Yuen Lee;  Guozhen Cui
Favorite |  | TC[WOS]:10 TC[Scopus]:11 | Submit date:2020/01/16
Antitumor  Biotin-conjugated Adtm Analog (Baa)  Cardioprotection  Cardiotoxicity  Doxorubicin (Dox)  
Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation Journal article
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Zhang, Chao;  Feng, Yu;  Tang, Fan;  Hoi, Maggie Pui-Man;  He, Chengwei;  Zheng, Ying;  Lee, Simon Ming-Yuen
Favorite |  | TC[WOS]:26 TC[Scopus]:29 | Submit date:2018/10/30
Schisantherin a  Neuroinflammation  Microglia  Nrf2  Nf-kappa b  
BHDPC is a novel neuroprotectant that provides anti-neuroinflammatory and neuroprotective effects by inactivating NF-κB and activating PKA/CREB Journal article
Frontiers in Pharmacology, 2018,Volume: 9,Issue: JUN
Authors:  Chuwen Li;  Tongkai Chen;  Hefeng Zhou;  Yu Feng;  Maggie P. M. Hoi;  Dan Ma;  Chao Zhao;  Ying Zheng;  Simon M. Y. Lee
Favorite |  | TC[WOS]:12 TC[Scopus]:14 | Submit date:2018/11/06
Bhdpc  Creb  Microglia  Neuroinflammation  Nf-κb  Pka  
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:  Li, Chuwen;  Chen, Tongkai;  Zhou, Hefeng;  Feng, Yu;  Hoi, Maggie P. M.;  Ma, Dan;  Zhao, Chao;  Zheng, Ying;  Lee, Simon M. Y.
Favorite |  | TC[WOS]:12 TC[Scopus]:14 | Submit date:2018/10/30
Bhdpc  Neuroinflammation  Microglia  Nf-kappa b  Creb  Pka  
Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKK beta-Dependent AMPK Activation Journal article
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018,Volume: 11
Authors:  Li, Chuwen;  Zhang, Chao;  Zhou, Hefeng;  Feng, Yu;  Tang, Fan;  Hoi, Maggie P. M.;  He, Chengwei;  Ma, Dan;  Zhao, Chao;  Lee, Simon M. Y.
Favorite |  | TC[WOS]:41 TC[Scopus]:43 | Submit date:2018/10/30
Amp-activated Protein Kinase  Betulinic Acid  Calmodulin-dependent Protein Kinase Beta  Microglia Polarization  Neuroinflammation