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Oxyphylla a promotes degradation of α-synuclein for neuroprotection via activation of immunoproteasome
Journal article
Aging and Disease, 2020,Volume: 11,Issue: 3,Page: 559-574
Authors:
Zhou,Hefeng
;
Li,Shengnan
;
Li,Chuwen
;
Yang,Xuanjun
;
Li,Haitao
;
Zhong,Hanbing
;
Lu,Jia Hong
;
Lee,Simon Ming Yuen
Favorite
|
|
TC[WOS]:
1
TC[Scopus]:
1
|
Submit date:2021/03/01
Degradation
Neuroprotection
Parkinson's disease
Proteasome
α-synuclein
Tetramethylpyrazine Analogue T-006 Promotes the Clearance of Alpha-synuclein by Enhancing Proteasome Activity in Parkinson’s Disease Models
Journal article
Neurotherapeutics, 2019,Volume: 16,Issue: 4,Page: 1225-1236
Authors:
Zhou,Hefeng
;
Shao,Min
;
Guo,Baojian
;
Li,Chuwen
;
Lu,Yucong
;
Yang,Xuanjun
;
ShengnanLi,
;
Li,Haitao
;
Zhu,Qi
;
Zhong,Hanbing
;
Wang,Yuqiang
;
Zhang,Zaijun
;
Lu,Jiahong
;
Lee,Simon Ming Yuen
Favorite
|
|
TC[WOS]:
7
TC[Scopus]:
7
|
Submit date:2021/03/01
Degradation
LMP7
Parkinson’s disease
Proteasome activity
α-synuclein
A novel agent attenuates cardiotoxicity and improves antitumor activity of doxorubicin in breast cancer cells
Journal article
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019,Volume: 120,Issue: 4,Page: 5913-5922
Authors:
Ying Zhang
;
Hongkuan Deng
;
Hefeng Zhou
;
Yucong Lu
;
Luchen Shan
;
Simon Ming‐Yuen Lee
;
Guozhen Cui
Favorite
|
|
TC[WOS]:
7
TC[Scopus]:
7
|
Submit date:2020/01/16
Antitumor
Biotin-conjugated Adtm Analog (Baa)
Cardioprotection
Cardiotoxicity
Doxorubicin (Dox)
Tetramethylpyrazine Analogue T-006 Exerts Neuroprotective Effects against 6-Hydroxydopamine-Induced Parkinson's Disease In Vitro and In Vivo
Journal article
Oxidative Medicine and Cellular Longevity, 2019,Volume: 2019
Authors:
Zhou,Hefeng
;
Shao,Min
;
Yang,Xuanjun
;
Li,Chuwen
;
Cui,Guozhen
;
Gao,Cheng
;
Di,Lijun
;
Zhong,Hanbing
;
Wang,Yuqiang
;
Zhang,Zaijun
;
Lee,Simon Ming Yuen
Favorite
|
|
TC[WOS]:
5
TC[Scopus]:
5
|
Submit date:2021/03/01
Schisantherin a attenuates neuroinflammation in activated microglia: Role of Nrf2 activation through ERK phosphorylation
Journal article
Cellular Physiology and Biochemistry, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:
Li,Chuwen
;
Chen,Tongkai
;
Zhou,Hefeng
;
Zhang,Chao
;
Feng,Yu
;
Tang,Fan
;
Hoi,Maggie Pui Man
;
He,Chengwei
;
Zheng,Ying
;
Lee,Simon Ming Yuen
Favorite
|
|
TC[WOS]:
20
TC[Scopus]:
21
|
Submit date:2021/03/01
Microglia
Neuroinflammation
NF-κB
Nrf2
Schisantherin A
BHDPC Is a Novel Neuroprotectant That Provides Anti-neuroinflammatory and Neuroprotective Effects by Inactivating NF-kappa B and Activating PKA/CREB
Journal article
FRONTIERS IN PHARMACOLOGY, 2018,Volume: 9
Authors:
Li, Chuwen
;
Chen, Tongkai
;
Zhou, Hefeng
;
Feng, Yu
;
Hoi, Maggie P. M.
;
Ma, Dan
;
Zhao, Chao
;
Zheng, Ying
;
Lee, Simon M. Y.
Favorite
|
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TC[WOS]:
7
TC[Scopus]:
8
|
Submit date:2018/10/30
Bhdpc
Neuroinflammation
Microglia
Nf-kappa b
Creb
Pka
Inhibitory Effects of Betulinic Acid on LPS-Induced Neuroinflammation Involve M2 Microglial Polarization via CaMKK beta-Dependent AMPK Activation
Journal article
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018,Volume: 11
Authors:
Li, Chuwen
;
Zhang, Chao
;
Zhou, Hefeng
;
Feng, Yu
;
Tang, Fan
;
Hoi, Maggie P. M.
;
He, Chengwei
;
Ma, Dan
;
Zhao, Chao
;
Lee, Simon M. Y.
Favorite
|
|
TC[WOS]:
28
TC[Scopus]:
28
|
Submit date:2018/10/30
Amp-activated Protein Kinase
Betulinic Acid
Calmodulin-dependent Protein Kinase Beta
Microglia Polarization
Neuroinflammation
A novel compound DT-010 protects against doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by inhibiting reactive oxygen species-mediated apoptotic and autophagic pathways
Journal article
EUROPEAN JOURNAL OF PHARMACOLOGY, 2018,Volume: 820,Page: 86-96
Authors:
Tang, Fan
;
Zhou, Xinhua
;
Wang, Liang
;
Shan, Luchen
;
Li, Chuwen
;
Zhou, Hefeng
;
Lee, Simon Ming-Yuen
;
Hoi, Maggie Pui-Man
Favorite
|
|
TC[WOS]:
23
TC[Scopus]:
21
|
Submit date:2018/10/30
Cardioprotection
Anti-oxidative Stress
Anti-apoptosis
Autophagy Regulation
Zebrafish Cardiotoxicity
H9c2 Cardiomyocytes
Schisantherin A Attenuates Neuroinflammation in Activated Microglia: Role of Nrf2 Activation Through ERK Phosphorylation
Journal article
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2018,Volume: 47,Issue: 5,Page: 1769-1784
Authors:
Li, Chuwen
;
Chen, Tongkai
;
Zhou, Hefeng
;
Zhang, Chao
;
Feng, Yu
;
Tang, Fan
;
Hoi, Maggie Pui-Man
;
He, Chengwei
;
Zheng, Ying
;
Lee, Simon Ming-Yuen
Favorite
|
|
TC[WOS]:
20
TC[Scopus]:
21
|
Submit date:2018/10/30
Schisantherin a
Neuroinflammation
Microglia
Nrf2
Nf-kappa b
Evaluation in zebrafish model of the toxicity of rhodamine B-conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics
Journal article
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2017,Volume: 31,Issue: 11
Authors:
Chan, Judy Yuet-Wa
;
Zhou, Hefeng
;
Kwan, Yiu Wa
;
Chan, Shun Wan
;
Radis-Baptista, Gandhi
;
Lee, Simon Ming-Yuen
Favorite
|
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TC[WOS]:
7
TC[Scopus]:
9
|
Submit date:2018/10/30
Acute Toxicity
Rhodamine B-crotamine
Screening Of Pharmaceuticals
Venom-derived Peptides
Zebrafish Model