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A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease Journal article
Autophagy, 2022,Volume: 18,Issue: 4,Page: 939-941
Authors:  Ai, Ruixue;  Zhuang, Xu Xu;  Anisimov, Alexander;  Lu, Jia Hong;  Fang, Evandro F.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/05/17
Aging  Alzheimer’s Disease  Autophagy  Machine Learning  Mitophagy  
A synergized machine learning plus cross-species wet-lab validation approach identifies neuronal mitophagy inducers inhibiting Alzheimer disease Other
2022-01-01
Authors:  Ai, Ruixue;  Zhuang, Xu Xu;  Anisimov, Alexander;  Lu, Jia Hong;  Fang, Evandro F.
Favorite |  | TC[WOS]:0 TC[Scopus]:0 | Submit date:2022/08/05
Aging  Alzheimer’s disease  autophagy  machine learning  mitophagy  
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow Journal article
Nature Biomedical Engineering, 2022,Volume: 6,Issue: 1,Page: 76-93
Authors:  Xie, Chenglong;  Zhuang, Xu Xu;  Niu, Zhangming;  Ai, Ruixue;  Lautrup, Sofie;  Zheng, Shuangjia;  Jiang, Yinghui;  Han, Ruiyu;  Gupta, Tanima Sen;  Cao, Shuqin;  Lagartos-Donate, Maria Jose;  Cai, Cui Zan;  Xie, Li Ming;  Caponio, Domenica;  Wang, Wen Wen;  Schmauck-Medina, Tomas;  Zhang, Jianying;  Wang, He ling;  Lou, Guofeng;  Xiao, Xianglu;  Zheng, Wenhua;  Palikaras, Konstantinos;  Yang, Guang;  Caldwell, Kim A.;  Caldwell, Guy A.;  Shen, Han Ming;  Nilsen, Hilde;  Lu, Jia Hong;  Fang, Evandro F.
Favorite |  | TC[WOS]:18 TC[Scopus]:21 | Submit date:2022/02/21
Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models Journal article
Theranostics, 2022,Volume: 12,Issue: 4,Page: 1738-1755
Authors:  Cai, Cui Zan;  Zhuang, Xu Xu;  Zhu, Qi;  Wu, Ming Yue;  Su, Huanxing;  Wang, Xiao Jin;  Iyaswamy, Ashok;  Yue, Zhenyu;  Wang, Qian;  Zhang, Bin;  Xue, Yu;  Tan, Jieqiong;  Li, Min;  He, Huanhuan;  Lu, Jia Hong
Favorite |  | TC[WOS]:0 TC[Scopus]:1 | Submit date:2022/05/17
Alzheimer's Disease  Autophagy    Ccz1-mon1a  Rab7  
Lycorine, a natural alkaloid, promotes the degradation of alpha-synuclein via PKA-mediated UPS activation in transgenic Parkinson's disease models Journal article
Phytomedicine, 2021,Volume: 87
Authors:  Zhu, Qi;  Zhuang, Xu xu;  Chen, Jia yue;  Yuan, Ning ning;  Chen, Yan;  Cai, Cui zan;  Tan, Jie qiong;  Su, Huan xing;  Lu, Jia hong
Favorite |  | TC[WOS]:4 TC[Scopus]:4 | Submit date:2021/12/08
Camp/pka Pathway  Lycorine  Parkinson's Disease  Ubiquitin-proteasome System  Α-synuclein  
Evidence of magneto-structural coupling during the spin reorientation process in TmFeO3 single crystal Journal article
Journal of Magnetism and Magnetic Materials, 2021,Volume: 523
Authors:  Cao, Yiming;  Zhuang, Qianfeng;  Wei, Shengxian;  Yin, Xunqing;  Liu, Hongwei;  Zhang, Yuanlei;  Kang, Yanru;  He, Xijia;  Liu, Mian;  Cao, Shixun;  Yang, Ya;  Li, Zhe;  Xu, Kun
Favorite |  | TC[WOS]:1 TC[Scopus]:2 | Submit date:2021/12/07
Hydrostatic Pressure  Magneto-structural Coupling  Rare-earth Orthoferrites  Spin Reorientation  
Surfactant-stripped J-aggregates of azaBODIPY derivatives: All-in-one phototheranostics in the second near infrared window Journal article
Journal of Controlled Release, 2020,Volume: 326,Page: 256-264
Authors:  Zhang,Yicheng;  Tao,Huiquan;  Li,Quguang;  Sheng,Wanle;  Xu,Yuejuan;  Hao,Erhong;  Chen,Meiwan;  Liu,Zhuang;  Feng,Liangzhu
Favorite |  | TC[WOS]:10 TC[Scopus]:10 | Submit date:2021/03/01
All-in-one Nir-ii Phototheranostics  Imaging Guided Cancer Combination Therapy  Nir-ii Boosted Photothermal Therapy  Nir-ii Fluorescence/photoacoustic Imaging  Surfactant-stripped Hbp J-aggregates  
The Chromosome Level Genome and Genome-wide Association Study for the Agronomic Traits of Panax Notoginseng Journal article
iScience, 2020,Volume: 23,Issue: 9
Authors:  Fan, Guangyi;  Liu, Xiaochuan;  Sun, Shuai;  Shi, Chengcheng;  Du, Xiao;  Han, Kai;  Yang, Binrui;  Fu, Yuanyuan;  Liu, Minghua;  Seim, Inge;  Zhang, He;  Xu, Qiwu;  Wang, Jiahao;  Su, Xiaoshan;  Shao, Libin;  Zhu, Yuanfang;  Shao, Yunchang;  Zhao, Yunpeng;  Wong, Andrew KC;  Zhuang, Dennis;  Chen, Wenbin;  Zhang, Gengyun;  Yang, Huanming;  Xu, Xun;  Tsui, Stephen Kwok Wing;  Liu, Xin;  Lee, Simon Ming Yue
Favorite |  | TC[WOS]:18 TC[Scopus]:19 | Submit date:2021/12/06
Biological Sciences  Genomics  Plant Biology  Transcriptomics  
NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation Journal article
Autophagy, 2020,Volume: 17,Issue: 5,Page: 1112-1130
Authors:  Cai,Cui Zan;  Yang,Chuanbin;  Zhuang,Xu Xu;  Yuan,Ning Ning;  Wu,Ming Yue;  Tan,Jie Qiong;  Song,Ju Xian;  Cheung,King Ho;  Su,Huanxing;  Wang,Yi Tao;  Tang,Bei Sha;  Behrends,Christian;  Durairajan,Siva Sundara Kumar;  Yue,Zhenyu;  Li,Min;  Lu,Jia Hong
Favorite |  | TC[WOS]:14 TC[Scopus]:15 | Submit date:2021/03/01
Amaturation  Autophagy  Ccz1-mon1a  Nrbf2  Pi3kc3  Rab7  Trafficking  Vps34  
Conducting concurrent electroencephalography and functional near-infrared spectroscopy recordings with a flanker task Journal article
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2020,Issue: 159
Authors:  Xu,Shi Yang;  Cheong,Lai Ian;  Zhuang,Yin;  Couto,Tania Alexandra Pinho;  Yuan,Zhen
Favorite |  | TC[WOS]:1 TC[Scopus]:1 | Submit date:2021/03/04
Neuroscience  Issue 159  Electroencephalography (Eeg)  Functional Near-infrared Spectroscopy (Fnirs)  Fusion  Flanker Task  Brain Activation