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J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice
Journal article
European Journal of Pharmaceutical Sciences, 2024,Volume: 194,Page: 1-18
Authors:
Pan, Zhijian
;
Shao, Min
;
Zhao, Chen
;
Yang, Xuanjun
;
Li, Haitao
; et al.
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TC[WOS]:
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TC[Scopus]:
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Submit date:2024/04/02
6-ohda
J24335
Mitochondria Dysfunction
Neurotoxicity
Parkinson's Disease
Target Prediction
Paraptosis: a non-classical paradigm of cell death for cancer therapy
Review article
2024
Authors:
Xu, Chun cao
;
Lin, Yi fan
;
Huang, Mu yang
;
Zhang, Xiao lei
;
Wang, Pei
; et al.
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TC[WOS]:
4
TC[Scopus]:
4
|
Submit date:2024/02/22
Cancer Therapy
Endoplasmic Reticulum
Er Stress
Mitochondria
Paraptosis
Antagonizing pathological α-synuclein-mediated neurodegeneration by J24335 via the activation of immunoproteasome
Journal article
Toxicology and Applied Pharmacology, 2023,Volume: 480,Page: 116745
Authors:
Pan, Zhijian
;
Yu, Chao Wu
;
Zhao, Chen
;
Shao, Min
;
Yang, Xuanjun
; et al.
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TC[WOS]:
0
TC[Scopus]:
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Submit date:2024/01/02
Immunoproteasome
J24335
Lmp7
Parkinson's Disease
Protein Degradation
Α-synuclein
Characteristics of clinical trials of new oncology drugs approved in China
Review article
2023
Authors:
Jing Yang
;
Ji Yang
;
HU YUANJIA
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TC[WOS]:
1
TC[Scopus]:
1
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Submit date:2024/01/02
Clinical Evidence
Drug Lag
Novel Anticancer Drugs
Pivotal Clinical Trials
Programmed Death-1 (Pd-1) Inhibitors
Programmed Death-ligand 1 (Pd-l1) Inhibitors
Ginsenoside Rh2 augmented anti-PD-L1 immunotherapy by reinvigorating CD8+ T cells via increasing intratumoral CXCL10
Journal article
Pharmacological Research, 2023,Volume: 198,Page: 106988
Authors:
Huang, Mu Yang
;
Chen, Yu Chi
;
Lyu, Wen Yu
;
He, Xin Yu
;
Ye, Zi Han
; et al.
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TC[WOS]:
0
TC[Scopus]:
1
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Submit date:2024/01/02
Combination Treatment
Ginsenoside Rh2
Pd-1/pd-l1
t Cells
Tumor Microenvironment
Exosomal miRNA-155-5p from M1-polarized macrophages suppresses angiogenesis by targeting GDF6 to interrupt diabetic wound healing
Journal article
Molecular Therapy Nucleic Acids, 2023,Volume: 34,Page: 102074
Authors:
Lou, Ruohan
;
Chen, Jiali
;
Zhou, Fei
;
Zhang, Tian
;
Chen, Xiuping
; et al.
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TC[WOS]:
1
TC[Scopus]:
1
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Submit date:2024/01/02
Angiogenesis
Diabetic Wound Healing
Growth Differentiation Factor 6
Microrna Expression Profiles
Mt: Oligonucleotides: Therapies And Applications
Polarized Macrophage-derived Exosomes
Thermosensitive Hydrogel
Identification of Bulbocodin D and C as novel STAT3 inhibitors and their anticancer activities in lung cancer cells
Journal article
Chinese Journal of Natural Medicines, 2023,Volume: 21,Issue: 11,Page: 842-851
Authors:
HE, Xinyu
;
FU, Jiarui
;
LYU, Wenyu
;
HUANG, Muyang
;
MO, Jianshan
; et al.
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2024/01/10
Bulbocodin c
Bulbocodin d
Cancer
Erk
Natural Products
Stat3
Comparative analysis of disease modelling for health economic evaluations of systemic therapies in advanced hepatocellular carcinoma
Journal article
PLoS ONE, 2023,Volume: 18,Issue: 10 October,Page: e0292239
Authors:
Zou, Huimin
;
Xue, Yan
;
Chen, Xianwen
;
Lai, Yunfeng
;
Yao, Dongning
; et al.
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2023/11/01
Benchmarking Drug Regulatory Systems for Capacity Building: An Integrative Review of Tools, Practice, and Recommendations
Journal article
International Journal of Health Policy and Management, 2023,Volume: 12,Issue: 1,Page: 8100
Authors:
Shi, Junnan
;
Chen, Xianwen
;
Hu, Hao
;
Ung, Carolina Oi Lam
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TC[WOS]:
0
TC[Scopus]:
0
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Submit date:2024/02/22
Capacity Building
Drug Regulatory Systems
Global Benchmarking Tool
National Regulatory Authorities
Regulatory Capacity
Therapeutic potential of TNFR2 agonists: a mechanistic perspective
Journal article
Frontiers in Immunology, 2023,Volume: 14,Page: 1209188
Authors:
Yibo Chen
;
Mengmeng Jiang
;
Xin Chen
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TC[WOS]:
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Submit date:2023/08/31
Treg - Regulatory t Cell
Tnfr2 Agonism
Tnfr2
Tumor
Autoimmune Diseases