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Profiling patent compounds in lipid nanoparticle formulations of siRNA Journal article
Han, Yunfeng, Wang, Mengyang, Chen, Yu, Ouyang, Defang, Zheng, Ying, Hu, Yuanjia. Profiling patent compounds in lipid nanoparticle formulations of siRNA[J]. Molecular Therapy Nucleic Acids, 2024, 35(4), 102362.
Authors:  Han, Yunfeng;  Wang, Mengyang;  Chen, Yu;  Ouyang, Defang;  Zheng, Ying; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.5/6.7 | Submit date：2024/12/05
Uncover the anticancer potential of lycorine Journal article
Zhang, Yan Ming, Li, Ting, Xu, Chun Cao, Qian, Jia Yu, Guo, Hongwei, Zhang, Xiaolei, Zhan, Zha Jun, Lu, Jin Jian. Uncover the anticancer potential of lycorine[J]. Chinese Medicine (United Kingdom), 2024, 19(1), 121.
Authors:  Zhang, Yan Ming;  Li, Ting;  Xu, Chun Cao;  Qian, Jia Yu;  Guo, Hongwei; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1 | Submit date：2024/10/10
Anticancer Mechanism  Lycorine  Lycorine Hydrochloride  Pharmacokinetics  Target  
Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics Journal article
Zhao, Moxuan, Xie, Junhong, Zhang, Jiaxiang, Zhao, Bosen, Zhang, Yue, Xue, Jinglong, Zhang, Ruxuan, Zhang, Ruiyang, Wang, Hongou, Li, Yanbo, Ge, Wei, Zhou, Xianqing. Disturbance of mitochondrial dynamics led to spermatogenesis disorder in mice exposed to polystyrene micro- and nanoplastics[J]. Environmental Pollution, 2024, 362, 124935.
Authors:  Zhao, Moxuan;  Xie, Junhong;  Zhang, Jiaxiang;  Zhao, Bosen;  Zhang, Yue; et al.
Favorite | TC[WOS]:1 TC[Scopus]:1  IF:7.6/8.3 | Submit date：2024/10/10
Apoptosis  Male Reproductive Toxicity  Mitochondrial Dynamics  Polystyrene Microplastics  Polystyrene Nanoplastics  Pyroptosis  
Aspirin reduces Ponatinib-induced cardiovascular toxic phenotypes and death in zebrafish Journal article
Yu, Ruiqi, Ai, Nana, Huang, Chen, Wang, Danni, Bian, Chao, Ge, Wei, Chong, Cheong Meng. Aspirin reduces Ponatinib-induced cardiovascular toxic phenotypes and death in zebrafish[J]. Biomedicine and Pharmacotherapy, 2024, 180, 117503.
Authors:  Yu, Ruiqi;  Ai, Nana;  Huang, Chen;  Wang, Danni;  Bian, Chao; et al.
Favorite | TC[Scopus]:0  IF:6.9/6.8 | Submit date：2024/10/10
Aspirin  Cardiovascular Toxicity  Cox-1  Ponatinib  Thrombosis  Zebrafish  
Endothelial Dysfunctions in Blood–Brain Barrier Breakdown in Alzheimer's Disease: From Mechanisms to Potential Therapies Review article
2024
Authors:  Yue, Qian;  Leng, Xinyue;  Xie, Ningqing;  Zhang, Zaijun;  Yang, Deguang; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.8/5.9 | Submit date：2024/12/05
Alzheimer's Disease  Bbb Protection  Blood–brain Barrier  Influx And Efflux Transporter  Paracellular Permeability  Vascular Inflammation  
Neutrophil-Mimetic Upconversion Photosynthetic Nanosystem Derived from Microalgae for Targeted Treatment of Thromboembolic Stroke Journal article
Quan, Xingping, Liu, Chang, Chen, Jinfen, Li, Yiyang, Yuan, Zhen, Zheng, Ying, Mok, Greta S.P., Wang, Ruibing, Zhao, Yonghua. Neutrophil-Mimetic Upconversion Photosynthetic Nanosystem Derived from Microalgae for Targeted Treatment of Thromboembolic Stroke[J]. ACS Nano, 2024, 18(44), 30307−30320.
Authors:  Quan, Xingping;  Liu, Chang;  Chen, Jinfen;  Li, Yiyang;  Yuan, Zhen; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:15.8/16.2 | Submit date：2024/11/05
Neutrophil-mimetic  Microalgae Thylakoid  Upconversion Nanoparticles  Nir-ii Laser  Atp/nadph Production  Endothelial Protection  
Artemisinin attenuates astrocyte overactivation by inhibiting IRE1 phosphorylation and the downstream NF-κB pathway in Alzheimer‘s disease Presentation
会议地点: 第11届亚洲自由基研究国际会议-2024中国氧化还原生物学与医学大会-北京市昆泰酒店, 会议日期: 2024-10-21-23, 报告日期: 2024-10-22
Authors:  ZHENG WENHUA
Favorite |  | Submit date：2024/08/22
HSPD1 Supports Osteosarcoma Progression through Stabilizing ATP5A1 and thus Activation of AKT/mTOR Signaling Journal article
Zhang, Yiming, Pan, Ruilin, Li, Kun, Cheang, Lek Hang, Zhao, Jing, Zhong, Zhangfeng, Li, Shaoping, Wang, Jinghao, Zhang, Xiaofang, Cheng, Yanmei, Zheng, Xiaofei, He, Rongrong, Wang, Huajun. HSPD1 Supports Osteosarcoma Progression through Stabilizing ATP5A1 and thus Activation of AKT/mTOR Signaling[J]. International Journal of Biological Sciences, 2024, 20(13), 5162-5190.
Authors:  Zhang, Yiming;  Pan, Ruilin;  Li, Kun;  Cheang, Lek Hang;  Zhao, Jing; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:8.2/8.3 | Submit date：2024/11/05
Atp5a1  Hspd1  Multiomics Analysis  Osteosarcoma  Oxidative Phosphorylation  Ubiquitination  
Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents Journal article
Wu, Puhua, Zhang, Zhicheng, Zhou, Yan, Liu, Quan, Tam, Kin Yip, Su, Zhenhong. Novel Dichloroacetophenone-Based PDHK1 Inhibitors as Potent Anticancer Agents[J]. DRUG DESIGN DEVELOPMENT AND THERAPY, 2024, 18, 4661-4679.
Authors:  Wu, Puhua;  Zhang, Zhicheng;  Zhou, Yan;  Liu, Quan;  Tam, Kin Yip; et al.
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:4.7/4.8 | Submit date：2024/11/05
Pdhk1  Dichloroacetophenone  Allosteric Pocket  Anti-nsclc Activity  Tumor Xenograft Mouse Model  
Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling Journal article
Zhang, Guiliang, Liang, Zirong, Wang, Yuqiang, Zhang, Zaijun, Hoi, Pui Man. Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling[J]. Antioxidants, 2024, 13(10), 1272.
Authors:  Zhang, Guiliang;  Liang, Zirong;  Wang, Yuqiang;  Zhang, Zaijun;  Hoi, Pui Man
Favorite | TC[WOS]:0 TC[Scopus]:0  IF:6.0/6.7 | Submit date：2024/12/05
Tetramethylpyrazine Analogue T-006  Oxidative Cytotoxicity  Excessive Glutamate  Ogd/r  Pi3k/akt  Nrf2/ho-1  Mtor